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Immunotargeting of Antigen xCT Attenuates Stem-like Cell Behavior and Metastatic Progression in Breast Cancer.

Lanzardo S, Conti L, Rooke R, Ruiu R, Accart N, Bolli E, Arigoni M, Macagno M, Barrera G, Pizzimenti S, Aurisicchio L, Calogero RA, Cavallo F.

Cancer Res. 2016 Jan 1;76(1):62-72. doi: 10.1158/0008-5472.CAN-15-1208.


Revisiting fixation and embedding techniques for optimal detection of dendritic cell subsets in tissues.

Accart N, Sergi F, Rooke R.

J Histochem Cytochem. 2014 Sep;62(9):661-71. doi: 10.1369/0022155414539963.


Yeast virus-derived stimulator of the innate immune system augments the efficacy of virus vector-based immunotherapy.

Claudepierre MC, Hortelano J, Schaedler E, Kleinpeter P, Geist M, Remy-Ziller C, Brandely R, Tosch C, Laruelle L, Jawhari A, Menguy T, Marchand JB, Romby P, Schultz P, Hartmann G, Rooke R, Bonnefoy JY, Preville X, Rittner K.

J Virol. 2014 May;88(10):5242-55. doi: 10.1128/JVI.03819-13.


Can calcium signaling be harnessed for cancer immunotherapy?

Rooke R.

Biochim Biophys Acta. 2014 Oct;1843(10):2334-40. doi: 10.1016/j.bbamcr.2014.01.034. Review.


Immunological characterization of a modified vaccinia virus Ankara vector expressing the human papillomavirus 16 E1 protein.

Remy-Ziller C, Germain C, Spindler A, Hoffmann C, Silvestre N, Rooke R, Bonnefoy JY, Préville X.

Clin Vaccine Immunol. 2014 Feb;21(2):147-55. doi: 10.1128/CVI.00678-13.


Miniature inverted-repeat transposable elements: discovery, distribution, and activity.

Fattash I, Rooke R, Wong A, Hui C, Luu T, Bhardwaj P, Yang G.

Genome. 2013 Sep;56(9):475-86. doi: 10.1139/gen-2012-0174. Review.


Lymphocytic infiltration in the cutaneous lymphoma microenvironment after injection of TG1042.

Accart N, Urosevic-Maiwald M, Dummer R, Bataille V, Kehrer N, Niculescu C, Limacher JM, Chenard MP, Bonnefoy JY, Rooke R.

J Transl Med. 2013 Sep 25;11:226. doi: 10.1186/1479-5876-11-226.


Therapeutic effects of anti-CD115 monoclonal antibody in mouse cancer models through dual inhibition of tumor-associated macrophages and osteoclasts.

Fend L, Accart N, Kintz J, Cochin S, Reymann C, Le Pogam F, Marchand JB, Menguy T, Slos P, Rooke R, Fournel S, Bonnefoy JY, Préville X, Haegel H.

PLoS One. 2013 Sep 3;8(9):e73310. doi: 10.1371/journal.pone.0073310.


A unique anti-CD115 monoclonal antibody which inhibits osteolysis and skews human monocyte differentiation from M2-polarized macrophages toward dendritic cells.

Haegel H, Thioudellet C, Hallet R, Geist M, Menguy T, Le Pogam F, Marchand JB, Toh ML, Duong V, Calcei A, Settelen N, Preville X, Hennequi M, Grellier B, Ancian P, Rissanen J, Clayette P, Guillen C, Rooke R, Bonnefoy JY.

MAbs. 2013 Sep-Oct;5(5):736-47. doi: 10.4161/mabs.25743.


HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 monochain transgenic/H-2 class I null mice: novel versatile preclinical models of human T cell responses.

Boucherma R, Kridane-Miledi H, Bouziat R, Rasmussen M, Gatard T, Langa-Vives F, Lemercier B, Lim A, Bérard M, Benmohamed L, Buus S, Rooke R, Lemonnier FA.

J Immunol. 2013 Jul 15;191(2):583-93. doi: 10.4049/jimmunol.1300483.


Therapeutic cancer vaccines in the treatment of non-small-cell lung cancer.

Limacher JM, Spring-Giusti C, Bellon N, Ancian P, Rooke R, Bonnefoy JY.

Expert Rev Vaccines. 2013 Mar;12(3):263-70. doi: 10.1586/erv.13.14. Review.


TLR2 ligation protects effector T cells from regulatory T-cell mediated suppression and repolarizes T helper responses following MVA-based cancer immunotherapy.

Amiset L, Fend L, Gatard-Scheikl T, Rittner K, Duong V, Rooke R, Muller S, Bonnefoy JY, Préville X, Haegel H.

Oncoimmunology. 2012 Nov 1;1(8):1271-1280.


ATon, abundant novel nonautonomous mobile genetic elements in yellow fever mosquito (Aedes aegypti).

Yang G, Wong A, Rooke R.

BMC Genomics. 2012 Jun 27;13:283. doi: 10.1186/1471-2164-13-283.


Spinal cord stimulation protects against atrial fibrillation induced by tachypacing.

Bernstein SA, Wong B, Vasquez C, Rosenberg SP, Rooke R, Kuznekoff LM, Lader JM, Mahoney VM, Budylin T, Älvstrand M, Rakowski-Anderson T, Bharmi R, Shah R, Fowler S, Holmes D, Farazi TG, Chinitz LA, Morley GE.

Heart Rhythm. 2012 Sep;9(9):1426-33.e3. doi: 10.1016/j.hrthm.2012.04.038.


The immunogenicity of the tumor-associated antigen α-fetoprotein is enhanced by a fusion with a transmembrane domain.

Tran L, Judor JP, Gauttier V, Geist M, Hoffman C, Rooke R, Vassaux G, Conchon S.

J Biomed Biotechnol. 2012;2012:878657. doi: 10.1155/2012/878657.


Bioinformatics and genomic analysis of transposable elements in eukaryotic genomes.

Janicki M, Rooke R, Yang G.

Chromosome Res. 2011 Aug;19(6):787-808. doi: 10.1007/s10577-011-9230-7.


TE Displayer for post-genomic analysis of transposable elements.

Rooke R, Yang G.

Bioinformatics. 2011 Jan 15;27(2):286-7. doi: 10.1093/bioinformatics/btq639.


In vivo preclinical low-field MRI monitoring of tumor growth following a suicide-gene therapy in an orthotopic mice model of human glioblastoma.

Breton E, Goetz C, Kintz J, Accart N, Aubertin G, Grellier B, Erbs P, Rooke R, Constantinesco A, Choquet P.

C R Biol. 2010 Mar;333(3):220-5. doi: 10.1016/j.crvi.2009.12.012.


Multicenter clinical experience with an atrial lead designed to minimize far-field R-wave sensing.

Fung JW, Sperzel J, Yu CM, Chan JY, Gelder RN, Yang MX, Rooke R, Boileau P, Fröhlig G.

Europace. 2009 May;11(5):618-24. doi: 10.1093/europace/eup078.


Lumbar discitis.

Date AR, Rooke R, Sivashankar S.

Arch Dis Child. 2006 Feb;91(2):116. No abstract available.

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