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Items: 1 to 20 of 29


Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate.

Vazquez-Martin A, Van den Haute C, Cufí S, Corominas-Faja B, Cuyàs E, Lopez-Bonet E, Rodriguez-Gallego E, Fernández-Arroyo S, Joven J, Baekelandt V, Menendez JA.

Aging (Albany NY). 2016 Jul;8(7):1330-52. doi: 10.18632/aging.100976.


Exploring the Process of Energy Generation in Pathophysiology by Targeted Metabolomics: Performance of a Simple and Quantitative Method.

Riera-Borrull M, Rodríguez-Gallego E, Hernández-Aguilera A, Luciano F, Ras R, Cuyàs E, Camps J, Segura-Carretero A, Menendez JA, Joven J, Fernández-Arroyo S.

J Am Soc Mass Spectrom. 2016 Jan;27(1):168-77. doi: 10.1007/s13361-015-1262-3. Epub 2015 Sep 17.


The acute impact of polyphenols from Hibiscus sabdariffa in metabolic homeostasis: an approach combining metabolomics and gene-expression analyses.

Beltrán-Debón R, Rodríguez-Gallego E, Fernández-Arroyo S, Senan-Campos O, Massucci FA, Hernández-Aguilera A, Sales-Pardo M, Guimerà R, Camps J, Menendez JA, Joven J.

Food Funct. 2015 Sep;6(9):2957-66. doi: 10.1039/c5fo00696a.


Liver fat deposition and mitochondrial dysfunction in morbid obesity: An approach combining metabolomics with liver imaging and histology.

Calvo N, Beltrán-Debón R, Rodríguez-Gallego E, Hernández-Aguilera A, Guirro M, Mariné-Casadó R, Millá L, Alegret JM, Sabench F, del Castillo D, Vinaixa M, Rodríguez MÀ, Correig X, García-Álvarez R, Menendez JA, Camps J, Joven J.

World J Gastroenterol. 2015 Jun 28;21(24):7529-44. doi: 10.3748/wjg.v21.i24.7529.


Immunohistochemical analysis of paraoxonases and chemokines in arteries of patients with peripheral artery disease.

Hernández-Aguilera A, Sepúlveda J, Rodríguez-Gallego E, Guirro M, García-Heredia A, Cabré N, Luciano-Mateo F, Fort-Gallifa I, Martín-Paredero V, Joven J, Camps J.

Int J Mol Sci. 2015 May 18;16(5):11323-38. doi: 10.3390/ijms160511323.


Oncometabolic mutation IDH1 R132H confers a metformin-hypersensitive phenotype.

Cuyàs E, Fernández-Arroyo S, Corominas-Faja B, Rodríguez-Gallego E, Bosch-Barrera J, Martin-Castillo B, De Llorens R, Joven J, Menendez JA.

Oncotarget. 2015 May 20;6(14):12279-96.


Understanding the role of circulating chemokine (C-C motif) ligand 2 in patients with chronic ischemia threatening the lower extremities.

Rull A, Hernandez-Aguilera A, Fibla M, Sepulveda J, Rodríguez-Gallego E, Riera-Borrull M, Sirvent JJ, Martín-Paredero V, Menendez JA, Camps J, Joven J.

Vasc Med. 2014 Dec;19(6):442-51. doi: 10.1177/1358863X14554034. Epub 2014 Oct 21.


Autophagy is an inflammation-related defensive mechanism against disease.

Joven J, Guirro M, Mariné-Casadó R, Rodríguez-Gallego E, Menéndez JA.

Adv Exp Med Biol. 2014;824:43-59. doi: 10.1007/978-3-319-07320-0_6. Review.


Oncobiguanides: Paracelsus' law and nonconventional routes for administering diabetobiguanides for cancer treatment.

Menendez JA, Quirantes-Piné R, Rodríguez-Gallego E, Cufí S, Corominas-Faja B, Cuyàs E, Bosch-Barrera J, Martin-Castillo B, Segura-Carretero A, Joven J.

Oncotarget. 2014 May 15;5(9):2344-8.


Paraoxonases and chemokine (C-C motif) ligand-2 in noncommunicable diseases.

Camps J, Rodríguez-Gallego E, García-Heredia A, Triguero I, Riera-Borrull M, Hernández-Aguilera A, Luciano-Mateo F, Fernández-Arroyo S, Joven J.

Adv Clin Chem. 2014;63:247-308. Review.


Mapping of the circulating metabolome reveals α-ketoglutarate as a predictor of morbid obesity-associated non-alcoholic fatty liver disease.

Rodríguez-Gallego E, Guirro M, Riera-Borrull M, Hernández-Aguilera A, Mariné-Casadó R, Fernández-Arroyo S, Beltrán-Debón R, Sabench F, Hernández M, del Castillo D, Menendez JA, Camps J, Ras R, Arola L, Joven J.

Int J Obes (Lond). 2015 Feb;39(2):279-87. doi: 10.1038/ijo.2014.53. Epub 2014 Mar 28.


Hibiscus sabdariffa extract lowers blood pressure and improves endothelial function.

Joven J, March I, Espinel E, Fernández-Arroyo S, Rodríguez-Gallego E, Aragonès G, Beltrán-Debón R, Alonso-Villaverde C, Rios L, Martin-Paredero V, Menendez JA, Micol V, Segura-Carretero A, Camps J.

Mol Nutr Food Res. 2014 Jun;58(6):1374-8. doi: 10.1002/mnfr.201300774. Epub 2014 Feb 24.


Acquired resistance to metformin in breast cancer cells triggers transcriptome reprogramming toward a degradome-related metastatic stem-like profile.

Oliveras-Ferraros C, Vazquez-Martin A, Cuyàs E, Corominas-Faja B, Rodríguez-Gallego E, Fernández-Arroyo S, Martin-Castillo B, Joven J, Menendez JA.

Cell Cycle. 2014;13(7):1132-44. doi: 10.4161/cc.27982. Epub 2014 Feb 7.


Rosiglitazone and fenofibrate exacerbate liver steatosis in a mouse model of obesity and hyperlipidemia. A transcriptomic and metabolomic study.

Rull A, Geeraert B, Aragonès G, Beltrán-Debón R, Rodríguez-Gallego E, García-Heredia A, Pedro-Botet J, Joven J, Holvoet P, Camps J.

J Proteome Res. 2014 Mar 7;13(3):1731-43. doi: 10.1021/pr401230s. Epub 2014 Jan 30.


Ubiquitous transgenic overexpression of C-C chemokine ligand 2: a model to assess the combined effect of high energy intake and continuous low-grade inflammation.

Rodríguez-Gallego E, Riera-Borrull M, Hernández-Aguilera A, Mariné-Casadó R, Rull A, Beltrán-Debón R, Luciano-Mateo F, Menendez JA, Vazquez-Martin A, Sirvent JJ, Martín-Paredero V, Corbí AL, Sierra-Filardi E, Aragonès G, García-Heredia A, Camps J, Alonso-Villaverde C, Joven J.

Mediators Inflamm. 2013;2013:953841. doi: 10.1155/2013/953841. Epub 2013 Dec 15.


Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin.

Cufí S, Corominas-Faja B, Lopez-Bonet E, Bonavia R, Pernas S, López IÁ, Dorca J, Martínez S, López NB, Fernández SD, Cuyàs E, Visa J, Rodríguez-Gallego E, Quirantes-Piné R, Segura-Carretero A, Joven J, Martin-Castillo B, Menendez JA.

Oncotarget. 2013 Sep;4(9):1484-95.


A possible role for CCR5 in the progression of atherosclerosis in HIV-infected patients: a cross-sectional study.

Fernández-Sender L, Alonso-Villaverde C, Rull A, Rodríguez-Gallego E, Riera-Borrull M, Hernández-Aguilera A, Camps J, Beltrán-Debón R, Aragonès G, Menendez JA, Joven J.

AIDS Res Ther. 2013 May 9;10(1):11. doi: 10.1186/1742-6405-10-11.


Mitochondrial dysfunction: a basic mechanism in inflammation-related non-communicable diseases and therapeutic opportunities.

Hernández-Aguilera A, Rull A, Rodríguez-Gallego E, Riera-Borrull M, Luciano-Mateo F, Camps J, Menéndez JA, Joven J.

Mediators Inflamm. 2013;2013:135698. doi: 10.1155/2013/135698. Epub 2013 Feb 28. Review.


Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents.

Menendez JA, Joven J, Aragonès G, Barrajón-Catalán E, Beltrán-Debón R, Borrás-Linares I, Camps J, Corominas-Faja B, Cufí S, Fernández-Arroyo S, Garcia-Heredia A, Hernández-Aguilera A, Herranz-López M, Jiménez-Sánchez C, López-Bonet E, Lozano-Sánchez J, Luciano-Mateo F, Martin-Castillo B, Martin-Paredero V, Pérez-Sánchez A, Oliveras-Ferraros C, Riera-Borrull M, Rodríguez-Gallego E, Quirantes-Piné R, Rull A, Tomás-Menor L, Vazquez-Martin A, Alonso-Villaverde C, Micol V, Segura-Carretero A.

Cell Cycle. 2013 Feb 15;12(4):555-78. doi: 10.4161/cc.23756. Epub 2013 Jan 31.


Metformin: a cheap and well-tolerated drug that provides benefits for viral infections.

Joven J, Menéndez JA, Fernandez-Sender L, Espinel E, Rull A, Beltrán-Debón R, Rodríguez-Gallego E, Riera-Borrull M, Pedro-Botet J, Alonso-Villaverde C, Camps J, Aragonès G.

HIV Med. 2013 Apr;14(4):233-40. doi: 10.1111/hiv.12000. Epub 2012 Nov 21.

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