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Items: 1 to 20 of 209

1.

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.

McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium.; Schizophrenia Working Group of the Psychiatric Genomics Consortium..

Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038/ncomms14774.

2.

Novel procedure with improved resolution and specificity for amplification and differentiation of variants of the gene encoding carboxylesterase 1.

Bjerre D, Rasmussen HB; INDICES Consortium..

Pharmacogenet Genomics. 2017 Apr;27(4):155-158. doi: 10.1097/FPC.0000000000000267.

PMID:
28146010
3.

The impact of CES1 genotypes on the pharmacokinetics of methylphenidate in healthy Danish subjects.

Stage C, Jürgens G, Guski LS, Thomsen R, Bjerre D, Ferrero-Miliani L, Lyauk YK, Rasmussen HB, Dalhoff K; INDICES Consortium..

Br J Clin Pharmacol. 2017 Jan 14. doi: 10.1111/bcp.13237. [Epub ahead of print]

PMID:
28087982
4.

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium.; Psychosis Endophenotypes International Consortium..

Nat Genet. 2017 Jan;49(1):27-35. doi: 10.1038/ng.3725. Epub 2016 Nov 21.

PMID:
27869829
5.

Nomenclature for alleles of the human carboxylesterase 1 gene.

Rasmussen HB, Madsen MB, Hansen PR; INDICES Consortium..

Pharmacogenet Genomics. 2017 Feb;27(2):78-80. doi: 10.1097/FPC.0000000000000255. No abstract available.

PMID:
27831961
6.

Population Pharmacokinetics of Methylphenidate in Healthy Adults Emphasizing Novel and Known Effects of Several Carboxylesterase 1 (CES1) Variants.

Lyauk YK, Stage C, Bergmann TK, Ferrero-Milliani L, Bjerre D, Thomsen R, Dalhoff KP, Rasmussen HB, Jürgens G.

Clin Transl Sci. 2016 Dec;9(6):337-345. doi: 10.1111/cts.12423. Epub 2016 Oct 18.

7.

Systems genetics analysis of pharmacogenomics variation during antidepressant treatment.

Madsen MB, Kogelman LJ, Kadarmideen HN, Rasmussen HB.

Pharmacogenomics J. 2016 Oct 18. doi: 10.1038/tpj.2016.68. [Epub ahead of print]

PMID:
27752142
8.

The metabolic syndrome among Danish seafarers: a follow-up study.

Jepsen JR, Rasmussen HB.

Int Marit Health. 2016;67(3):129-36. doi: 10.5603/IMH.2016.0025.

9.

Pharmacodynamic Impact of Carboxylesterase 1 Gene Variants in Patients with Congestive Heart Failure Treated with Angiotensin-Converting Enzyme Inhibitors.

Nelveg-Kristensen KE, Bie P, Ferrero L, Bjerre D, Bruun NE, Egfjord M, Rasmussen HB, Hansen PR; INDICES Consortium..

PLoS One. 2016 Sep 23;11(9):e0163341. doi: 10.1371/journal.pone.0163341. eCollection 2016.

10.

Investigating the impact of missense mutations in hCES1 by in silico structure-based approaches.

Nzabonimpa GS, Rasmussen HB, Brunak S, Taboureau O; INDICES Consortium..

Drug Metab Pers Ther. 2016 Feb 19. pii: /j/dmdi.ahead-of-print/dmpt-2015-0034/dmpt-2015-0034.xml. doi: 10.1515/dmpt-2015-0034. [Epub ahead of print]

PMID:
26900165
11.

Switch in Therapy from Methylphenidate to Atomoxetine in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: An Analysis of Patient Records.

Warrer P, Thomsen PH, Dalsgaard S, Hansen EH, Aagaard L, Wallach Kildemoes H, Rasmussen HB.

J Child Adolesc Psychopharmacol. 2016 May;26(4):354-61. doi: 10.1089/cap.2015.0060. Epub 2016 Feb 18.

12.

Live Imaging of Kv7.2/7.3 Cell Surface Dynamics at the Axon Initial Segment: High Steady-State Stability and Calpain-Dependent Excitotoxic Downregulation Revealed.

Benned-Jensen T, Christensen RK, Denti F, Perrier JF, Rasmussen HB, Olesen SP.

J Neurosci. 2016 Feb 17;36(7):2261-6. doi: 10.1523/JNEUROSCI.2631-15.2016.

13.

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.

Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJ, Arias-Vasquez A, Smoller JW, Nichols TE, Neale MC, McIntosh AM, Lee P, McMahon FJ, Meyer-Lindenberg A, Mattheisen M, Andreassen OA, Gruber O, Sachdev PS, Roiz-Santiañez R, Saykin AJ, Ehrlich S, Mather KA, Turner JA, Schwarz E, Thalamuthu A, Yao Y, Ho YY, Martin NG, Wright MJ; Schizophrenia Working Group of the Psychiatric Genomics Consortium.; Psychosis Endophenotypes International Consortium.; Wellcome Trust Case Control Consortium 2.; Enigma Consortium., O'Donovan MC, Thompson PM, Neale BM, Medland SE, Sullivan PF.

Nat Neurosci. 2016 Mar;19(3):420-31. doi: 10.1038/nn.4228. Epub 2016 Feb 1.

14.

Schizophrenia risk from complex variation of complement component 4.

Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; Schizophrenia Working Group of the Psychiatric Genomics Consortium., Daly MJ, Carroll MC, Stevens B, McCarroll SA.

Nature. 2016 Feb 11;530(7589):177-83. doi: 10.1038/nature16549. Epub 2016 Jan 27.

15.

Prognostic impact of carboxylesterase 1 gene variants in patients with congestive heart failure treated with angiotensin-converting enzyme inhibitors.

Nelveg-Kristensen KE, Madsen MB, Torp-Pedersen C, Køber L, Egfjord M, Hansen T, Pedersen O, Rasmussen HB, Hansen PR.

Pharmacogenet Genomics. 2016 Jan 12. [Epub ahead of print]

PMID:
26761119
16.

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness.

Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, Rietschel M, Cichon S, St Clair D, Corvin A, Kirov G, McQuillin A, Gurling H, Rujescu D, Andreassen OA, Werge T, Blackwood DH, Pato CN, Pato MT, Malhotra AK, O'Donovan MC, Kendler KS, Fanous AH; Schizophrenia Working Group of the Psychiatric Genomics Consortium..

Am J Med Genet B Neuropsychiatr Genet. 2016 Mar;171B(2):276-89. doi: 10.1002/ajmg.b.32402. Epub 2015 Dec 11.

PMID:
26663532
17.

Monoclonal Antibodies Follow Distinct Aggregation Pathways During Production-Relevant Acidic Incubation and Neutralization.

Skamris T, Tian X, Thorolfsson M, Karkov HS, Rasmussen HB, Langkilde AE, Vestergaard B.

Pharm Res. 2016 Mar;33(3):716-28. doi: 10.1007/s11095-015-1821-0. Epub 2015 Nov 12.

PMID:
26563206
18.

Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders.

Hoeffding LK, Duong LT, Ingason A, Rosengren A, Sorbanski E, Witt SH, Djurovic S, Andreassen OA, Hansen T, Werge T, Rasmussen HB.

Nord J Psychiatry. 2016;70(4):276-9. doi: 10.3109/08039488.2015.1095944. Epub 2015 Nov 11.

PMID:
26559242
19.

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis.

Loh PR, Bhatia G, Gusev A, Finucane HK, Bulik-Sullivan BK, Pollack SJ; Schizophrenia Working Group of Psychiatric Genomics Consortium., de Candia TR, Lee SH, Wray NR, Kendler KS, O'Donovan MC, Neale BM, Patterson N, Price AL.

Nat Genet. 2015 Dec;47(12):1385-92. doi: 10.1038/ng.3431. Epub 2015 Nov 2.

20.

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.

Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study., Kathiresan S, Pato M, Pato C, Tamimi R, Stahl E, Zaitlen N, Pasaniuc B, Belbin G, Kenny EE, Schierup MH, De Jager P, Patsopoulos NA, McCarroll S, Daly M, Purcell S, Chasman D, Neale B, Goddard M, Visscher PM, Kraft P, Patterson N, Price AL.

Am J Hum Genet. 2015 Oct 1;97(4):576-92. doi: 10.1016/j.ajhg.2015.09.001.

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