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Items: 1 to 20 of 316

1.

Oncolytic influenza virus infection restores immunocompetence of lung tumor-associated alveolar macrophages.

Masemann D, Köther K, Kuhlencord M, Varga G, Roth J, Lichty BD, Rapp UR, Wixler V, Ludwig S.

Oncoimmunology. 2018 Feb 12;7(5):e1423171. doi: 10.1080/2162402X.2017.1423171. eCollection 2018.

2.

Impaired neuronal maturation of hippocampal neural progenitor cells in mice lacking CRAF.

Pfeiffer V, Götz R, Camarero G, Heinsen H, Blum R, Rapp UR.

PLoS One. 2018 Mar 28;13(3):e0192067. doi: 10.1371/journal.pone.0192067. eCollection 2018.

3.

Cysts mark the early stage of metastatic tumor development in non-small cell lung cancer.

Thakur C, Rapp UR, Rudel T.

Oncotarget. 2017 Dec 30;9(5):6518-6535. doi: 10.18632/oncotarget.23785. eCollection 2018 Jan 19.

4.

Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk.

Pullamsetti SS, Kojonazarov B, Storn S, Gall H, Salazar Y, Wolf J, Weigert A, El-Nikhely N, Ghofrani HA, Krombach GA, Fink L, Gattenlöhner S, Rapp UR, Schermuly RT, Grimminger F, Seeger W, Savai R.

Sci Transl Med. 2017 Nov 15;9(416). pii: eaai9048. doi: 10.1126/scitranslmed.aai9048.

PMID:
29141888
5.

Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate.

Mehta A, Cordero J, Dobersch S, Romero-Olmedo AJ, Savai R, Bodner J, Chao CM, Fink L, Guzmán-Díaz E, Singh I, Dobreva G, Rapp UR, Günther S, Ilinskaya ON, Bellusci S, Dammann RH, Braun T, Seeger W, Gattenlöhner S, Tresch A, Günther A, Barreto G.

EMBO Mol Med. 2016 Dec 1;8(12):1380-1389. doi: 10.15252/emmm.201606382. Print 2016 Dec.

6.

Germline variant FGFR4  p.G388R exposes a membrane-proximal STAT3 binding site.

Ulaganathan VK, Sperl B, Rapp UR, Ullrich A.

Nature. 2015 Dec 24;528(7583):570-4. doi: 10.1038/nature16449. Epub 2015 Dec 16.

PMID:
26675719
7.

C-Raf deficiency leads to hearing loss and increased noise susceptibility.

de Iriarte Rodríguez R, Magariños M, Pfeiffer V, Rapp UR, Varela-Nieto I.

Cell Mol Life Sci. 2015 Oct;72(20):3983-98. doi: 10.1007/s00018-015-1919-x. Epub 2015 May 15.

8.

In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B.

Silva IT, Carvalho A, Lang KL, Dudek SE, Masemann D, Durán FJ, Caro MS, Rapp UR, Wixler V, Schenkel EP, Simões CM, Ludwig S.

PLoS One. 2015 Feb 12;10(2):e0117794. doi: 10.1371/journal.pone.0117794. eCollection 2015.

9.

Elimination of B-RAF in oncogenic C-RAF-expressing alveolar epithelial type II cells reduces MAPK signal intensity and lung tumor growth.

Zanucco E, El-Nikhely N, Götz R, Weidmann K, Pfeiffer V, Savai R, Seeger W, Ullrich A, Rapp UR.

J Biol Chem. 2014 Sep 26;289(39):26804-16. doi: 10.1074/jbc.M114.558999. Epub 2014 Aug 5.

10.

Tyr728 in the kinase domain of the murine kinase suppressor of RAS 1 regulates binding and activation of the mitogen-activated protein kinase kinase.

Sibilski C, Mueller T, Kollipara L, Zahedi RP, Rapp UR, Rudel T, Baljuls A.

J Biol Chem. 2013 Dec 6;288(49):35237-52. doi: 10.1074/jbc.M113.490235. Epub 2013 Oct 24.

11.

Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum.

Pfeiffer V, Götz R, Xiang C, Camarero G, Braun A, Zhang Y, Blum R, Heinsen H, Nieswandt B, Rapp UR.

PLoS One. 2013;8(3):e58259. doi: 10.1371/journal.pone.0058259. Epub 2013 Mar 7.

12.

E-cadherin controls bronchiolar progenitor cells and onset of preneoplastic lesions in mice.

Ceteci F, Ceteci S, Zanucco E, Thakur C, Becker M, El-Nikhely N, Fink L, Seeger W, Savai R, Rapp UR.

Neoplasia. 2012 Dec;14(12):1164-77.

13.

MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma.

Castro IC, Breiling A, Luetkenhaus K, Ceteci F, Hausmann S, Kress S, Lyko F, Rudel T, Rapp UR.

Mol Cancer Res. 2013 Feb;11(2):161-72. doi: 10.1158/1541-7786.MCR-12-0414-T. Epub 2012 Dec 13.

14.

MK3 controls Polycomb target gene expression via negative feedback on ERK.

Prickaerts P, Niessen HE, Mouchel-Vielh E, Dahlmans VE, van den Akker GG, Geijselaers C, Adriaens ME, Spaapen F, Takihara Y, Rapp UR, Peronnet F, Voncken JW.

Epigenetics Chromatin. 2012 Aug 7;5(1):12. doi: 10.1186/1756-8935-5-12.

15.

Role of melanoma inhibitor of apoptosis (ML-IAP) protein, a member of the baculoviral IAP repeat (BIR) domain family, in the regulation of C-RAF kinase and cell migration.

Oberoi-Khanuja TK, Karreman C, Larisch S, Rapp UR, Rajalingam K.

J Biol Chem. 2012 Aug 17;287(34):28445-55. doi: 10.1074/jbc.M112.341297. Epub 2012 Jun 18.

16.

The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAF.

Baljuls A, Beck M, Oenel A, Robubi A, Kroschewski R, Hekman M, Rudel T, Rapp UR.

J Biol Chem. 2012 Jun 29;287(27):23128-40. doi: 10.1074/jbc.M112.343780. Epub 2012 May 17.

17.

Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells.

Oak PS, Kopp F, Thakur C, Ellwart JW, Rapp UR, Ullrich A, Wagner E, Knyazev P, Roidl A.

Int J Cancer. 2012 Dec 15;131(12):2808-19. doi: 10.1002/ijc.27595. Epub 2012 May 21.

18.

Expression of B-RAF V600E in type II pneumocytes causes abnormalities in alveolar formation, airspace enlargement and tumor formation in mice.

Zanucco E, Götz R, Potapenko T, Carraretto I, Ceteci S, Ceteci F, Seeger W, Savai R, Rapp UR.

PLoS One. 2011;6(12):e29093. doi: 10.1371/journal.pone.0029093. Epub 2011 Dec 14.

20.

Specific antibody-receptor interactions trigger InlAB-independent uptake of Listeria monocytogenes into tumor cell lines.

Heisig M, Frentzen A, Bergmann B, Galmbacher K, Gentschev I, Hotz C, Schoen C, Stritzker J, Fensterle J, Rapp UR, Goebel W.

BMC Microbiol. 2011 Jul 11;11:163. doi: 10.1186/1471-2180-11-163.

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