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Items: 1 to 20 of 467

1.

CRISPR/Cas9-Mediated In Vitro Mutagenesis in GC-Like B Cells.

Chu VT, Graf R, Rajewsky K.

Methods Mol Biol. 2017;1623:135-145. doi: 10.1007/978-1-4939-7095-7_12.

PMID:
28589354
2.

The B-cell receptor controls fitness of MYC-driven lymphoma cells via GSK3β inhibition.

Varano G, Raffel S, Sormani M, Zanardi F, Lonardi S, Zasada C, Perucho L, Petrocelli V, Haake A, Lee AK, Bugatti M, Paul U, Van Anken E, Pasqualucci L, Rabadan R, Siebert R, Kempa S, Ponzoni M, Facchetti F, Rajewsky K, Casola S.

Nature. 2017 Jun 8;546(7657):302-306. doi: 10.1038/nature22353. Epub 2017 May 31.

3.

George Klein: 1925-2016.

Rajewsky K.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3275-3277. doi: 10.1073/pnas.1702501114. Epub 2017 Mar 13. No abstract available.

PMID:
28289211
4.

EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells.

Wanke F, Moos S, Croxford AL, Heinen AP, Gräf S, Kalt B, Tischner D, Zhang J, Christen I, Bruttger J, Yogev N, Tang Y, Zayoud M, Israel N, Karram K, Reißig S, Lacher SM, Reichhold C, Mufazalov IA, Ben-Nun A, Kuhlmann T, Wettschureck N, Sailer AW, Rajewsky K, Casola S, Waisman A, Kurschus FC.

Cell Rep. 2017 Jan 31;18(5):1270-1284. doi: 10.1016/j.celrep.2017.01.020.

5.

miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation.

Coffre M, Benhamou D, Rieß D, Blumenberg L, Snetkova V, Hines MJ, Chakraborty T, Bajwa S, Jensen K, Chong MM, Getu L, Silverman GJ, Blelloch R, Littman DR, Calado D, Melamed D, Skok JA, Rajewsky K, Koralov SB.

Cell Rep. 2016 Nov 22;17(9):2271-2285. doi: 10.1016/j.celrep.2016.11.006.

6.

Mouse model for acute Epstein-Barr virus infection.

Wirtz T, Weber T, Kracker S, Sommermann T, Rajewsky K, Yasuda T.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):13821-13826. Epub 2016 Nov 16.

7.

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.

Chu VT, Graf R, Wirtz T, Weber T, Favret J, Li X, Petsch K, Tran NT, Sieweke MH, Berek C, Kühn R, Rajewsky K.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12514-12519. Epub 2016 Oct 11.

8.

A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency.

Benhamou D, Labi V, Novak R, Dai I, Shafir-Alon S, Weiss A, Gaujoux R, Arnold R, Shen-Orr SS, Rajewsky K, Melamed D.

Cell Rep. 2016 Jul 12;16(2):419-31. doi: 10.1016/j.celrep.2016.05.084. Epub 2016 Jun 23.

9.

MiR-150 Controls B Cell Differentiation by Targeting the Transcription Factor c-Myb.

Xiao C, Calado DP, Galler G, Thai TH, Patterson HC, Wang J, Rajewsky N, Bender TP, Rajewsky K.

Cell. 2016 May 5;165(4):1027. doi: 10.1016/j.cell.2016.04.056. No abstract available.

10.

Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells.

Derudder E, Herzog S, Labi V, Yasuda T, Köchert K, Janz M, Villunger A, Schmidt-Supprian M, Rajewsky K.

Proc Natl Acad Sci U S A. 2016 May 3;113(18):5065-70. doi: 10.1073/pnas.1604529113. Epub 2016 Apr 20.

11.

Tissue-specific DNA demethylation is required for proper B-cell differentiation and function.

Orlanski S, Labi V, Reizel Y, Spiro A, Lichtenstein M, Levin-Klein R, Koralov SB, Skversky Y, Rajewsky K, Cedar H, Bergman Y.

Proc Natl Acad Sci U S A. 2016 May 3;113(18):5018-23. doi: 10.1073/pnas.1604365113. Epub 2016 Apr 18.

12.

Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function.

Levit-Zerdoun E, Becker M, Pohlmeyer R, Wilhelm I, Maity PC, Rajewsky K, Reth M, Hobeika E.

J Immunol. 2016 Mar 1;196(5):2348-60. doi: 10.4049/jimmunol.1501707. Epub 2016 Feb 3.

13.

miR-23∼27∼24 clusters control effector T cell differentiation and function.

Cho S, Wu CJ, Yasuda T, Cruz LO, Khan AA, Lin LL, Nguyen DT, Miller M, Lee HM, Kuo ML, Broide DH, Rajewsky K, Rudensky AY, Lu LF.

J Exp Med. 2016 Feb 8;213(2):235-49. doi: 10.1084/jem.20150990. Epub 2016 Feb 1.

14.

Immunological memory: lessons from the past and a look to the future.

Farber DL, Netea MG, Radbruch A, Rajewsky K, Zinkernagel RM.

Nat Rev Immunol. 2016 Feb;16(2):124-8. doi: 10.1038/nri.2016.13. Review.

PMID:
26831526
15.

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes.

Chu VT, Weber T, Graf R, Sommermann T, Petsch K, Sack U, Volchkov P, Rajewsky K, Kühn R.

BMC Biotechnol. 2016 Jan 16;16:4. doi: 10.1186/s12896-016-0234-4.

16.

FOXO1 couples metabolic activity and growth state in the vascular endothelium.

Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich MF, Lim R, Zimmermann B, Aspalter IM, Franco CA, Boettger T, Braun T, Fruttiger M, Rajewsky K, Keller C, Brüning JC, Gerhardt H, Carmeliet P, Potente M.

Nature. 2016 Jan 14;529(7585):216-20. doi: 10.1038/nature16498. Epub 2016 Jan 6.

17.

PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones.

Sander S, Chu VT, Yasuda T, Franklin A, Graf R, Calado DP, Li S, Imami K, Selbach M, Di Virgilio M, Bullinger L, Rajewsky K.

Immunity. 2015 Dec 15;43(6):1075-86. doi: 10.1016/j.immuni.2015.10.021. Epub 2015 Nov 24.

18.

Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.

Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, Browning JL, Goossens N, Nakagawa S, Gunasekaran G, Schwartz ME, Kobayashi M, Kumada H, Berger M, Pappo O, Rajewsky K, Hoshida Y, Karin M, Heikenwalder M, Ben-Neriah Y, Pikarsky E.

Nat Immunol. 2015 Dec;16(12):1235-44. doi: 10.1038/ni.3290. Epub 2015 Oct 26.

19.

Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence.

Akilli Öztürk Ö, Pakula H, Chmielowiec J, Qi J, Stein S, Lan L, Sasaki Y, Rajewsky K, Birchmeier W.

Cell Rep. 2015 Oct 20;13(3):561-72. doi: 10.1016/j.celrep.2015.09.015. Epub 2015 Oct 8.

20.

The B-cell antigen receptor integrates adaptive and innate immune signals.

Otipoby KL, Waisman A, Derudder E, Srinivasan L, Franklin A, Rajewsky K.

Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):12145-50. doi: 10.1073/pnas.1516428112. Epub 2015 Sep 14.

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