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Items: 1 to 20 of 34

1.

Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.

Koyani CN, Trummer C, Shrestha N, Scheruebel S, Bourgeois B, Plastira I, Kickmaier S, Sourij H, Rainer PP, Madl T, Sattler W, Pelzmann B, Malle E, von Lewinski D.

Front Physiol. 2018 Nov 14;9:1622. doi: 10.3389/fphys.2018.01622. eCollection 2018.

2.

Reply: Elevated Cardiac Troponin T in Skeletal Myopathies: Skeletal TnT Cross-Reactivity and/or Cardiac TnT Expression?

Schmid J, Birner-Grünberger R, Quasthoff S, Binder JS, Rainer PP.

J Am Coll Cardiol. 2018 Jul 17;72(3):349-350. doi: 10.1016/j.jacc.2018.05.019. Epub 2018 Jul 9. No abstract available.

PMID:
30012332
3.

A novel LMNA nonsense mutation causes two distinct phenotypes of cardiomyopathy with high risk of sudden cardiac death in a large five-generation family.

Glöcklhofer CR, Steinfurt J, Franke G, Hoppmann A, Glantschnig T, Perez-Feliz S, Alter S, Fischer J, Brunner M, Rainer PP, Köttgen A, Bode C, Odening KE.

Europace. 2018 Dec 1;20(12):2003-2013. doi: 10.1093/europace/euy127.

PMID:
29947763
4.

Elevated Cardiac Troponin T in Patients With Skeletal Myopathies.

Schmid J, Liesinger L, Birner-Gruenberger R, Stojakovic T, Scharnagl H, Dieplinger B, Asslaber M, Radl R, Beer M, Polacin M, Mair J, Szolar D, Berghold A, Quasthoff S, Binder JS, Rainer PP.

J Am Coll Cardiol. 2018 Apr 10;71(14):1540-1549. doi: 10.1016/j.jacc.2018.01.070.

5.

The Anti-Cancer Multikinase Inhibitor Sorafenib Impairs Cardiac Contractility by Reducing Phospholamban Phosphorylation and Sarcoplasmic Calcium Transients.

Schneider C, Wallner M, Kolesnik E, Herbst V, Mächler H, Pichler M, von Lewinski D, Sedej S, Rainer PP.

Sci Rep. 2018 Mar 28;8(1):5295. doi: 10.1038/s41598-018-23630-w.

6.

Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure.

Rainer PP, Dong P, Sorge M, Fert-Bober J, Holewinski RJ, Wang Y, Foss CA, An SS, Baracca A, Solaini G, Glabe CG, Pomper MG, Van Eyk JE, Tomaselli GF, Paolocci N, Agnetti G.

Circ Res. 2018 May 11;122(10):e75-e83. doi: 10.1161/CIRCRESAHA.117.312082. Epub 2018 Feb 26.

PMID:
29483093
7.

A New Murine Model of Chronic Kidney Disease-Mineral and Bone Disorder.

Frauscher B, Artinger K, Kirsch AH, Aringer I, Moschovaki-Filippidou F, Kétszeri M, Schabhüttl C, Rainer PP, Schmidt A, Stojakovic T, Fahrleitner-Pammer A, Rosenkranz AR, Eller P, Eller K.

Int J Endocrinol. 2017;2017:1659071. doi: 10.1155/2017/1659071. Epub 2017 Dec 14.

8.

Unfolding Cardiac Amyloidosis - From Pathophysiology to Cure.

Ablasser K, Verheyen N, Glantschnig T, Agnetti G, Rainer PP.

Curr Med Chem. 2018 Jan 4. doi: 10.2174/0929867325666180104153338. [Epub ahead of print]

PMID:
29303069
9.

Dipeptidyl peptidase-4 independent cardiac dysfunction links saxagliptin to heart failure.

Koyani CN, Kolesnik E, Wölkart G, Shrestha N, Scheruebel S, Trummer C, Zorn-Pauly K, Hammer A, Lang P, Reicher H, Maechler H, Groschner K, Mayer B, Rainer PP, Sourij H, Sattler W, Malle E, Pelzmann B, von Lewinski D.

Biochem Pharmacol. 2017 Dec 1;145:64-80. doi: 10.1016/j.bcp.2017.08.021. Epub 2017 Aug 30.

10.

Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice.

Rouf R, MacFarlane EG, Takimoto E, Chaudhary R, Nagpal V, Rainer PP, Bindman JG, Gerber EE, Bedja D, Schiefer C, Miller KL, Zhu G, Myers L, Amat-Alarcon N, Lee DI, Koitabashi N, Judge DP, Kass DA, Dietz HC.

JCI Insight. 2017 Aug 3;2(15). pii: 91588. doi: 10.1172/jci.insight.91588. [Epub ahead of print]

11.

ST2 predicts survival in patients undergoing transcatheter aortic valve implantation.

Schmid J, Stojakovic T, Zweiker D, Scharnagl H, Maderthaner RD, Scherr D, Maier R, Schmidt A, März W, Binder JS, Rainer PP.

Int J Cardiol. 2017 Oct 1;244:87-92. doi: 10.1016/j.ijcard.2017.06.066. Epub 2017 Jun 19.

PMID:
28651919
12.

Istaroxime, a potential anticancer drug in prostate cancer, exerts beneficial functional effects in healthy and diseased human myocardium.

Wallner M, Khafaga M, Kolesnik E, Vafiadis A, Schwantzer G, Eaton DM, Curcic P, Köstenberger M, Knez I, Rainer PP, Pichler M, Pieske B, Lewinski DV.

Oncotarget. 2017 Jul 25;8(30):49264-49274. doi: 10.18632/oncotarget.17540.

13.

Targeted Next-Generation Sequencing Reveals Novel TTN Mutations Causing Recessive Distal Titinopathy.

Evilä A, Palmio J, Vihola A, Savarese M, Tasca G, Penttilä S, Lehtinen S, Jonson PH, De Bleecker J, Rainer P, Auer-Grumbach M, Pouget J, Salort-Campana E, Vilchez JJ, Muelas N, Olive M, Hackman P, Udd B.

Mol Neurobiol. 2017 Nov;54(9):7212-7223. doi: 10.1007/s12035-016-0242-3. Epub 2016 Oct 29.

PMID:
27796757
14.

Typical STEMI: or not? Embolic left anterior descending artery occlusion, fulminant pulmonary embolism, and in-transit thrombus in a patent foramen ovale.

Maier R, Krumnikl J, Knez I, Rainer PP.

Eur Heart J. 2016 Oct 21;37(40):3114. Epub 2016 Jun 28. No abstract available.

PMID:
27354045
15.

Old dog, new tricks: novel cardiac targets and stress regulation by protein kinase G.

Rainer PP, Kass DA.

Cardiovasc Res. 2016 Jul 15;111(2):154-62. doi: 10.1093/cvr/cvw107. Epub 2016 Jun 13. Review.

16.

Profilin modulates sarcomeric organization and mediates cardiomyocyte hypertrophy.

Kooij V, Viswanathan MC, Lee DI, Rainer PP, Schmidt W, Kronert WA, Harding SE, Kass DA, Bernstein SI, Van Eyk JE, Cammarato A.

Cardiovasc Res. 2016 May 15;110(2):238-48. doi: 10.1093/cvr/cvw050. Epub 2016 Mar 7.

17.

Bidirectional cross-regulation between ErbB2 and β-adrenergic signalling pathways.

Sysa-Shah P, Tocchetti CG, Gupta M, Rainer PP, Shen X, Kang BH, Belmonte F, Li J, Xu Y, Guo X, Bedja D, Gao WD, Paolocci N, Rath R, Sawyer DB, Naga Prasad SV, Gabrielson K.

Cardiovasc Res. 2016 Mar 1;109(3):358-73. doi: 10.1093/cvr/cvv274. Epub 2015 Dec 21.

18.

Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection.

Chung HS, Murray CI, Venkatraman V, Crowgey EL, Rainer PP, Cole RN, Bomgarden RD, Rogers JC, Balkan W, Hare JM, Kass DA, Van Eyk JE.

Circ Res. 2015 Oct 23;117(10):846-57. doi: 10.1161/CIRCRESAHA.115.307336. Epub 2015 Sep 3.

19.

Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease.

Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo SH, Danner T, Zhang M, Rainer PP, Bedja D, Kirk JA, Ranek MJ, Dostmann WR, Kwon C, Margulies KB, Van Eyk JE, Paulus WJ, Takimoto E, Kass DA.

Nature. 2015 Mar 26;519(7544):472-6. doi: 10.1038/nature14332. Epub 2015 Mar 18.

20.

Response to letter from Villa-Abrille et al.

Kass DA, Seo K, Rainer P.

Circ Res. 2015 Jan 2;116(1):e12. doi: 10.1161/CIRCRESAHA.114.305576. No abstract available.

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