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Items: 8


Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.

Gao L, Rabbitt EH, Condon JC, Renthal NE, Johnston JM, Mitsche MA, Chambon P, Xu J, O'Malley BW, Mendelson CR.

J Clin Invest. 2015 Jul 1;125(7):2808-24. doi: 10.1172/JCI78544. Epub 2015 Jun 22.


11β-Hydroxysteroid dehydrogenase blockade prevents age-induced skin structure and function defects.

Tiganescu A, Tahrani AA, Morgan SA, Otranto M, Desmoulière A, Abrahams L, Hassan-Smith Z, Walker EA, Rabbitt EH, Cooper MS, Amrein K, Lavery GG, Stewart PM.

J Clin Invest. 2013 Jul;123(7):3051-60. doi: 10.1172/JCI64162. Epub 2013 Jun 3.


Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis.

Hardy R, Juarez M, Naylor A, Tu J, Rabbitt EH, Filer A, Stewart PM, Buckley CD, Raza K, Cooper MS.

Arthritis Res Ther. 2012 Oct 18;14(5):R226. doi: 10.1186/ar4065.


Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.

Lavery GG, Zielinska AE, Gathercole LL, Hughes B, Semjonous N, Guest P, Saqib K, Sherlock M, Reynolds G, Morgan SA, Tomlinson JW, Walker EA, Rabbitt EH, Stewart PM.

Endocrinology. 2012 Jul;153(7):3236-48. doi: 10.1210/en.2012-1019. Epub 2012 May 3.


Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells.

Ahasan MM, Hardy R, Jones C, Kaur K, Nanus D, Juarez M, Morgan SA, Hassan-Smith Z, Bénézech C, Caamaño JH, Hewison M, Lavery G, Rabbitt EH, Clark AR, Filer A, Buckley CD, Raza K, Stewart PM, Cooper MS.

Arthritis Rheum. 2012 Jul;64(7):2404-13. doi: 10.1002/art.34414.


Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss.

Kaur K, Hardy R, Ahasan MM, Eijken M, van Leeuwen JP, Filer A, Thomas AM, Raza K, Buckley CD, Stewart PM, Rabbitt EH, Hewison M, Cooper MS.

Ann Rheum Dis. 2010 Jun;69(6):1185-90. doi: 10.1136/ard.2009.107466. Epub 2009 Jun 22.


Local and systemic glucocorticoid metabolism in inflammatory arthritis.

Hardy R, Rabbitt EH, Filer A, Emery P, Hewison M, Stewart PM, Gittoes NJ, Buckley CD, Raza K, Cooper MS.

Ann Rheum Dis. 2008 Sep;67(9):1204-10. doi: 10.1136/ard.2008.090662. Epub 2008 Apr 17.


Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation.

Hardy RS, Filer A, Cooper MS, Parsonage G, Raza K, Hardie DL, Rabbitt EH, Stewart PM, Buckley CD, Hewison M.

Arthritis Res Ther. 2006;8(4):R108.

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