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Comprehensive Analysis of E3 Ubiquitin Ligases Reveals Ring Finger Protein 223 as a Novel Oncogene Activated by KLF4 in Pancreatic Cancer.
Feng L, Wang J, Zhang J, Diao J, He L, Fu C, Liao H, Xu X, Gao Y, Zhou C. Feng L, et al. Front Cell Dev Biol. 2021 Oct 14;9:738709. doi: 10.3389/fcell.2021.738709. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34722520 Free PMC article.
RNF223 showed independent significance as an unfavorable prognostic marker and was chosen for subsequent analysis. Next, the function of RNF223 in the pancreatic cancer cell lines ASPC-1 and PANC-1 was investigated, and RNF223 silencing promoted pancreatic ca …
RNF223 showed independent significance as an unfavorable prognostic marker and was chosen for subsequent analysis. Next, the function …
Identification of a RNA-seq-based signature to improve prognostics for uterine sarcoma.
Zhou JG, Zhao HT, Jin SH, Tian X, Ma H. Zhou JG, et al. Gynecol Oncol. 2019 Dec;155(3):499-507. doi: 10.1016/j.ygyno.2019.08.033. Epub 2019 Oct 26. Gynecol Oncol. 2019. PMID: 31662204
RESULTS: This study identified a prognostic signature based on 6 genes: FGF23, TLX2, TIFAB, RNF223, HIST1H3A and AADACL4. In the training group, the median OS in the high- and low-risk groups was 19.6 vs 88.1 months (HR, 0.1412, 95% CI: 0.03295 - 0.6054; P = 0.002), respec …
RESULTS: This study identified a prognostic signature based on 6 genes: FGF23, TLX2, TIFAB, RNF223, HIST1H3A and AADACL4. In the trai …
Distinct clinical and genetic mutation characteristics in sporadic and Lynch syndrome-associated endometrial cancer in a Chinese population.
Sun P, Shen Y, Wang T, He Y, Zhang Y, Tian W, Yang B, Hu Y. Sun P, et al. Cancer Epidemiol. 2021 Aug;73:101934. doi: 10.1016/j.canep.2021.101934. Epub 2021 May 14. Cancer Epidemiol. 2021. PMID: 34000661
The average BMI of the suspected Lynch syndrome-associated endometrial cancer patients was 23.43 kg/m(2) (CI: 20, 30), which was lower than the 26.50 kg/m(2) of the sporadic endometrial cancer patients (P = 0.028). Combined with the WES data, MASP2, NADK and RNF223 were id …
The average BMI of the suspected Lynch syndrome-associated endometrial cancer patients was 23.43 kg/m(2) (CI: 20, 30), which was lower than …
Whole-genome assembly and annotation for the little yellow croaker (Larimichthys polyactis) provide insights into the evolution of hermaphroditism and gonochorism.
Xie QP, Zhan W, Shi JZ, Liu F, Niu BL, He X, Liu M, Wang J, Liang QQ, Xie Y, Xu P, Wang X, Lou B. Xie QP, et al. Mol Ecol Resour. 2023 Apr;23(3):632-658. doi: 10.1111/1755-0998.13731. Epub 2022 Nov 20. Mol Ecol Resour. 2023. PMID: 36330680
Transcriptome analysis showed that the expression of dmrt1 and its upstream regulatory gene (rnf183) were both sexually dimorphic. Rnf183, unlike its two paralogues rnf223 and rnf225, is only present in Larimichthys and Lates but not in other teleost species, suggesting th …
Transcriptome analysis showed that the expression of dmrt1 and its upstream regulatory gene (rnf183) were both sexually dimorphic. Rnf183, u …