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Items: 1 to 20 of 149

1.

Interferon-α coincides with suppressed levels of pentraxin-3 (PTX3) in systemic lupus erythematosus and regulates leukocyte PTX3 in vitro.

Wirestam L, Enocsson H, Skogh T, Eloranta ML, Rönnblom L, Sjöwall C, Wetterö J.

Clin Exp Immunol. 2017 Mar 3. doi: 10.1111/cei.12957. [Epub ahead of print]

PMID:
28257596
2.

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C, Dubnovitsky A, Sandin C, Kozhukh G, Uchtenhagen H, James EA, Rönnelid J, Ytterberg AJ, Pieper J, Reed E, Tandre C, Rieck M, Zubarev RA, Rönnblom L, Sandalova T, Buckner JH, Achour A, Malmström V.

Front Immunol. 2016 Nov 14;7:494.

3.

Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's disease.

Eriksson D, Bianchi M, Landegren N, Nordin J, Dalin F, Mathioudaki A, Eriksson GN, Hultin-Rosenberg L, Dahlqvist J, Zetterqvist H, Karlsson Å, Hallgren Å, Farias FH, Murén E, Ahlgren KM, Lobell A, Andersson G, Tandre K, Dahlqvist SR, Söderkvist P, Rönnblom L, Hulting AL, Wahlberg J, Ekwall O, Dahlqvist P, Meadows JR, Bensing S, Lindblad-Toh K, Kämpe O, Pielberg GR.

J Intern Med. 2016 Dec;280(6):595-608. doi: 10.1111/joim.12569.

PMID:
27807919
4.

Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells.

Morin A, Kwan T, Ge B, Letourneau L, Ban M, Tandre K, Caron M, Sandling JK, Carlsson J, Bourque G, Laprise C, Montpetit A, Syvanen AC, Ronnblom L, Sawcer SJ, Lathrop MG, Pastinen T.

BMC Med Genomics. 2016 Sep 13;9(1):59. doi: 10.1186/s12920-016-0220-7.

5.

The importance of the type I interferon system in autoimmunity.

Rönnblom L.

Clin Exp Rheumatol. 2016 Jul-Aug;34(4 Suppl 98):21-4. Review.

6.

DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands.

Wahlberg P, Lundmark A, Nordlund J, Busche S, Raine A, Tandre K, Rönnblom L, Sinnett D, Forestier E, Pastinen T, Lönnerholm G, Syvänen AC.

Epigenomics. 2016 Oct;8(10):1367-1387.

7.

Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.

Folkersen L, Brynedal B, Diaz-Gallo LM, Ramsköld D, Shchetynsky K, Westerlind H, Sundström Y, Schepis D, Hensvold A, Vivar N, Eloranta ML, Rönnblom L, Brunak S, Malmström V, Catrina A, Moerch UG, Klareskog L, Padyukov L, Berg L.

Mol Med. 2016 Aug 15;22. doi: 10.2119/molmed.2016.00078. [Epub ahead of print]

8.

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus.

Morris DL, Sheng Y, Zhang Y, Wang YF, Zhu Z, Tombleson P, Chen L, Cunninghame Graham DS, Bentham J, Roberts AL, Chen R, Zuo X, Wang T, Wen L, Yang C, Liu L, Yang L, Li F, Huang Y, Yin X, Yang S, Rönnblom L, Fürnrohr BG, Voll RE, Schett G, Costedoat-Chalumeau N, Gaffney PM, Lau YL, Zhang X, Yang W, Cui Y, Vyse TJ.

Nat Genet. 2016 Aug;48(8):940-6. doi: 10.1038/ng.3603.

9.

Systemic lupus erythematosus: still a challenge for physicians.

Bengtsson AA, Rönnblom L.

J Intern Med. 2017 Jan;281(1):52-64. doi: 10.1111/joim.12529. Review.

PMID:
27307107
10.

Cause and consequences of the activated type I interferon system in SLE.

Eloranta ML, Rönnblom L.

J Mol Med (Berl). 2016 Oct;94(10):1103-1110. Review.

11.

Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression.

Cavalli M, Pan G, Nord H, Wallerman O, Wallén Arzt E, Berggren O, Elvers I, Eloranta ML, Rönnblom L, Lindblad Toh K, Wadelius C.

Hum Genet. 2016 May;135(5):485-97. doi: 10.1007/s00439-016-1654-x.

12.

Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes.

Imgenberg-Kreuz J, Sandling JK, Almlöf JC, Nordlund J, Signér L, Norheim KB, Omdal R, Rönnblom L, Eloranta ML, Syvänen AC, Nordmark G.

Ann Rheum Dis. 2016 Nov;75(11):2029-2036. doi: 10.1136/annrheumdis-2015-208659.

13.

Effect of PTPN22 Gene Variant R620W on Type I Interferon Production Stimulated by Different Toll-like Receptor 7 Agonists: Comment on the Article by Wang et al.

Berggren O, Rönnblom L, Eloranta ML.

Arthritis Rheumatol. 2016 Apr;68(4):1045. doi: 10.1002/art.39571. No abstract available.

PMID:
26748951
14.

Direct and indirect costs for systemic lupus erythematosus in Sweden. A nationwide health economic study based on five defined cohorts.

Jönsen A, Hjalte F, Willim M, Carlsson KS, Sjöwall C, Svenungsson E, Leonard D, Bengtsson C, Rantapää-Dahlqvist S, Pettersson S, Gunnarsson I, Zickert A, Gustafsson JT, Rönnblom L, Petersson IF, Bengtsson AA, Nived O.

Semin Arthritis Rheum. 2016 Jun;45(6):684-90. doi: 10.1016/j.semarthrit.2015.11.013.

PMID:
26743074
15.

Case definitions in Swedish register data to identify systemic lupus erythematosus.

Arkema EV, Jönsen A, Rönnblom L, Svenungsson E, Sjöwall C, Simard JF.

BMJ Open. 2016 Jan 4;6(1):e007769. doi: 10.1136/bmjopen-2015-007769.

16.

A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis.

Chemin K, Pollastro S, James E, Ge C, Albrecht I, Herrath J, Gerstner C, Tandre K, Sampaio Rizzi T, Rönnblom L, Catrina A, Holmdahl R, Klareskog L, de Vries N, Malmström V.

Arthritis Rheumatol. 2016 May;68(5):1124-35. doi: 10.1002/art.39553.

PMID:
26713667
17.

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

Bentham J, Morris DL, Cunninghame Graham DS, Pinder CL, Tombleson P, Behrens TW, Martín J, Fairfax BP, Knight JC, Chen L, Replogle J, Syvänen AC, Rönnblom L, Graham RR, Wither JE, Rioux JD, Alarcón-Riquelme ME, Vyse TJ.

Nat Genet. 2015 Dec;47(12):1457-64. doi: 10.1038/ng.3434.

18.

Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes.

Leonard D, Eloranta ML, Hagberg N, Berggren O, Tandre K, Alm G, Rönnblom L.

Ann Rheum Dis. 2016 Sep;75(9):1728-34. doi: 10.1136/annrheumdis-2015-208055.

PMID:
26493814
19.

Erratum: Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.

Allum F, Shao X, Guénard F, Simon MM, Busche S, Caron M, Lambourne J, Lessard J, Tandre K, Hedman ÅK, Kwan T, Ge B; Multiple Tissue Human Expression Resource Consortium., Rönnblom L, McCarthy MI, Deloukas P, Richmond T, Burgess D, Spector TD, Tchernof A, Marceau S, Lathrop M, Vohl MC, Pastinen T, Grundberg E.

Nat Commun. 2015 Jul 29;6:8016. doi: 10.1038/ncomms9016. No abstract available.

PMID:
26219997
20.

Epigenome data release: a participant-centered approach to privacy protection.

Dyke SO, Cheung WA, Joly Y, Ammerpohl O, Lutsik P, Rothstein MA, Caron M, Busche S, Bourque G, Rönnblom L, Flicek P, Beck S, Hirst M, Stunnenberg H, Siebert R, Walter J, Pastinen T.

Genome Biol. 2015 Jul 17;16:142. doi: 10.1186/s13059-015-0723-0.

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