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Items: 1 to 20 of 36


Loss of Mitochondrial Ndufs4 in Striatal Medium Spiny Neurons Mediates Progressive Motor Impairment in a Mouse Model of Leigh Syndrome.

Chen B, Hui J, Montgomery KS, Gella A, Bolea I, Sanz E, Palmiter RD, Quintana A.

Front Mol Neurosci. 2017 Aug 24;10:265. doi: 10.3389/fnmol.2017.00265. eCollection 2017.


Striatal GPR88 Modulates Foraging Efficiency.

Rainwater A, Sanz E, Palmiter RD, Quintana A.

J Neurosci. 2017 Aug 16;37(33):7939-7947. doi: 10.1523/JNEUROSCI.2439-16.2017. Epub 2017 Jul 20.


Glutamatergic Neurotransmission Links Sensitivity to Volatile Anesthetics with Mitochondrial Function.

Zimin PI, Woods CB, Quintana A, Ramirez JM, Morgan PG, Sedensky MM.

Curr Biol. 2016 Aug 22;26(16):2194-201. doi: 10.1016/j.cub.2016.06.020. Epub 2016 Aug 4.


Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state.

Padilla SL, Qiu J, Soden ME, Sanz E, Nestor CC, Barker FD, Quintana A, Zweifel LS, Rønnekleiv OK, Kelly MJ, Palmiter RD.

Nat Neurosci. 2016 May;19(5):734-741. doi: 10.1038/nn.4274. Epub 2016 Mar 28.


Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome.

Piroli GG, Manuel AM, Clapper AC, Walla MD, Baatz JE, Palmiter RD, Quintana A, Frizzell N.

Mol Cell Proteomics. 2016 Feb;15(2):445-61. doi: 10.1074/mcp.M115.051516. Epub 2015 Oct 8.


Fertility-regulating Kiss1 neurons arise from hypothalamic POMC-expressing progenitors.

Sanz E, Quintana A, Deem JD, Steiner RA, Palmiter RD, McKnight GS.

J Neurosci. 2015 Apr 8;35(14):5549-56. doi: 10.1523/JNEUROSCI.3614-14.2015.


Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration.

Liu L, Zhang K, Sandoval H, Yamamoto S, Jaiswal M, Sanz E, Li Z, Hui J, Graham BH, Quintana A, Bellen HJ.

Cell. 2015 Jan 15;160(1-2):177-90. doi: 10.1016/j.cell.2014.12.019.


Absence of metallothionein-3 produces changes on MT-1/2 regulation in basal conditions and alters hypothalamic-pituitary-adrenal (HPA) axis.

Lago N, Quintana A, Carrasco J, Giralt M, Hidalgo J, Molinero A.

Neurochem Int. 2014 Jul;74:65-73. doi: 10.1016/j.neuint.2014.06.008. Epub 2014 Jun 24.


Muscle-specific interleukin-6 deletion influences body weight and body fat in a sex-dependent manner.

Ferrer B, Navia B, Giralt M, Comes G, Carrasco J, Molinero A, Quintana A, Señarís RM, Hidalgo J.

Brain Behav Immun. 2014 Aug;40:121-30. doi: 10.1016/j.bbi.2014.03.001. Epub 2014 Mar 12.


mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome.

Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, Morgan PG, Sedensky MM, Kaeberlein M.

Science. 2013 Dec 20;342(6165):1524-8. doi: 10.1126/science.1244360. Epub 2013 Nov 14.


RiboTag analysis of actively translated mRNAs in Sertoli and Leydig cells in vivo.

Sanz E, Evanoff R, Quintana A, Evans E, Miller JA, Ko C, Amieux PS, Griswold MD, McKnight GS.

PLoS One. 2013 Jun 11;8(6):e66179. doi: 10.1371/journal.pone.0066179. Print 2013.


Induction of atypical EAE mediated by transgenic production of IL-6 in astrocytes in the absence of systemic IL-6.

Giralt M, Ramos R, Quintana A, Ferrer B, Erta M, Castro-Freire M, Comes G, Sanz E, Unzeta M, Pifarré P, García A, Campbell IL, Hidalgo J.

Glia. 2013 Apr;61(4):587-600. doi: 10.1002/glia.22457. Epub 2013 Jan 16.


Interleukin-6, a major cytokine in the central nervous system.

Erta M, Quintana A, Hidalgo J.

Int J Biol Sci. 2012;8(9):1254-66. doi: 10.7150/ijbs.4679. Epub 2012 Oct 25. Review.


Astrocyte-specific deficiency of interleukin-6 and its receptor reveal specific roles in survival, body weight and behavior.

Quintana A, Erta M, Ferrer B, Comes G, Giralt M, Hidalgo J.

Brain Behav Immun. 2013 Jan;27(1):162-73. doi: 10.1016/j.bbi.2012.10.011. Epub 2012 Oct 17.


Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors.

Quintana A, Sanz E, Wang W, Storey GP, Güler AD, Wanat MJ, Roller BA, La Torre A, Amieux PS, McKnight GS, Bamford NS, Palmiter RD.

Nat Neurosci. 2012 Nov;15(11):1547-55. doi: 10.1038/nn.3239. Epub 2012 Oct 14.


Altered anesthetic sensitivity of mice lacking Ndufs4, a subunit of mitochondrial complex I.

Quintana A, Morgan PG, Kruse SE, Palmiter RD, Sedensky MM.

PLoS One. 2012;7(8):e42904. doi: 10.1371/journal.pone.0042904. Epub 2012 Aug 17.


Fatal breathing dysfunction in a mouse model of Leigh syndrome.

Quintana A, Zanella S, Koch H, Kruse SE, Lee D, Ramirez JM, Palmiter RD.

J Clin Invest. 2012 Jul;122(7):2359-68. doi: 10.1172/JCI62923. Epub 2012 Jun 1.


Severely impaired learning and altered neuronal morphology in mice lacking NMDA receptors in medium spiny neurons.

Beutler LR, Eldred KC, Quintana A, Keene CD, Rose SE, Postupna N, Montine TJ, Palmiter RD.

PLoS One. 2011;6(11):e28168. doi: 10.1371/journal.pone.0028168. Epub 2011 Nov 21.


Selective p38α MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction.

Bruchas MR, Schindler AG, Shankar H, Messinger DI, Miyatake M, Land BB, Lemos JC, Hagan CE, Neumaier JF, Quintana A, Palmiter RD, Chavkin C.

Neuron. 2011 Aug 11;71(3):498-511. doi: 10.1016/j.neuron.2011.06.011.


Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization.

Beutler LR, Wanat MJ, Quintana A, Sanz E, Bamford NS, Zweifel LS, Palmiter RD.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4206-11. doi: 10.1073/pnas.1101424108. Epub 2011 Feb 22.

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