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Items: 1 to 20 of 56


PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment.

Watts TL, Cui R, Szaniszlo P, Resto VA, Powell DW, Pinchuk IV.

J Transl Med. 2016 Dec 8;14(1):337.


Diabetic Nephropathy: Proteinuria, Inflammation, and Fibrosis.

Zheng S, Powell DW, Zheng F, Kantharidis P, Gnudi L.

J Diabetes Res. 2016;2016:5241549. doi: 10.1155/2016/5241549. Epub 2016 Jan 6. No abstract available.


Isolation of CD 90+ Fibroblast/Myofibroblasts from Human Frozen Gastrointestinal Specimens.

Johnson P, Beswick EJ, Chao C, Powell DW, Hellmich MR, Pinchuk IV.

J Vis Exp. 2016 Jan 31;(107):e53691. doi: 10.3791/53691.


Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice.

Zheng S, Coventry S, Cai L, Powell DW, Jala VR, Haribabu B, Epstein PN.

J Diabetes Res. 2016;2016:5362506. doi: 10.1155/2016/5362506. Epub 2015 Dec 20.


CD90(+) stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer.

Huynh PT, Beswick EJ, Coronado YA, Johnson P, O'Connell MR, Watts T, Singh P, Qiu S, Morris K, Powell DW, Pinchuk IV.

Int J Cancer. 2016 Apr 15;138(8):1971-81. doi: 10.1002/ijc.29939. Epub 2015 Dec 10.


Differential expression of endoplasmic reticulum stress-response proteins in different renal tubule subtypes of OVE26 diabetic mice.

Barati MT, Powell DW, Kechavarzi BD, Isaacs SM, Zheng S, Epstein PN, Cai L, Coventry S, Rane MJ, Klein JB.

Cell Stress Chaperones. 2016 Jan;21(1):155-66.


A20-Binding Inhibitor of NF-κB Activation 1 is a Physiologic Inhibitor of NF-κB: A Molecular Switch for Inflammation and Autoimmunity.

G'Sell RT, Gaffney PM, Powell DW.

Arthritis Rheumatol. 2015 Sep;67(9):2292-302. doi: 10.1002/art.39245. Review. No abstract available.


Changing the concepts of immune-mediated glomerular diseases through proteomics.

Caster DJ, Hobeika L, Klein JB, Powell DW, McLeish KR.

Proteomics Clin Appl. 2015 Dec;9(11-12):967-71. doi: 10.1002/prca.201400159. Epub 2015 Jun 17. Review.


Autoantibodies targeting glomerular annexin A2 identify patients with proliferative lupus nephritis.

Caster DJ, Korte EA, Merchant ML, Klein JB, Wilkey DW, Rovin BH, Birmingham DJ, Harley JB, Cobb BL, Namjou B, McLeish KR, Powell DW.

Proteomics Clin Appl. 2015 Dec;9(11-12):1012-20. doi: 10.1002/prca.201400175. Epub 2015 Jun 12.


Role of intestinal myofibroblasts in HIV-associated intestinal collagen deposition and immune reconstitution following combination antiretroviral therapy.

Asmuth DM, Pinchuk IV, Wu J, Vargas G, Chen X, Mann S, Albanese A, Ma ZM, Saroufeem R, Melcher GP, Troia-Cancio P, Torok NJ, Miller CJ, Powell DW.

AIDS. 2015 May 15;29(8):877-88. doi: 10.1097/QAD.0000000000000636.


TLR4 activation enhances the PD-L1-mediated tolerogenic capacity of colonic CD90+ stromal cells.

Beswick EJ, Johnson JR, Saada JI, Humen M, House J, Dann S, Qiu S, Brasier AR, Powell DW, Reyes VE, Pinchuk IV.

J Immunol. 2014 Sep 1;193(5):2218-29. doi: 10.4049/jimmunol.1203441. Epub 2014 Jul 28.


ABIN1 dysfunction as a genetic basis for lupus nephritis.

Caster DJ, Korte EA, Nanda SK, McLeish KR, Oliver RK, G'sell RT, Sheehan RM, Freeman DW, Coventry SC, Kelly JA, Guthridge JM, James JA, Sivils KL, Alarcon-Riquelme ME, Scofield RH, Adrianto I, Gaffney PM, Stevens AM, Freedman BI, Langefeld CD, Tsao BP, Pons-Estel BA, Jacob CO, Kamen DL, Gilkeson GS, Brown EE, Alarcon GS, Edberg JC, Kimberly RP, Martin J, Merrill JT, Harley JB, Kaufman KM, Reveille JD, Anaya JM, Criswell LA, Vila LM, Petri M, Ramsey-Goldman R, Bae SC, Boackle SA, Vyse TJ, Niewold TB, Cohen P, Powell DW.

J Am Soc Nephrol. 2013 Nov;24(11):1743-54. doi: 10.1681/ASN.2013020148. Epub 2013 Aug 22.


Associations between structural and functional changes to the kidney in diabetic humans and mice.

Powell DW, Kenagy DN, Zheng S, Coventry SC, Xu J, Cai L, Carlson EC, Epstein PN.

Life Sci. 2013 Aug 28;93(7):257-64. doi: 10.1016/j.lfs.2013.06.016. Epub 2013 Jun 22. Review.


Immunoproteomic analysis of potential serum biomarker candidates in human glaucoma.

Tezel G, Thornton IL, Tong MG, Luo C, Yang X, Cai J, Powell DW, Soltau JB, Liebmann JM, Ritch R.

Invest Ophthalmol Vis Sci. 2012 Dec 13;53(13):8222-31. doi: 10.1167/iovs.12-10076.


Antibacterial effect of microvesicles released from human neutrophilic granulocytes.

Timár CI, Lorincz AM, Csépányi-Kömi R, Vályi-Nagy A, Nagy G, Buzás EI, Iványi Z, Kittel A, Powell DW, McLeish KR, Ligeti E.

Blood. 2013 Jan 17;121(3):510-8. doi: 10.1182/blood-2012-05-431114. Epub 2012 Nov 8.


An astrocyte-specific proteomic approach to inflammatory responses in experimental rat glaucoma.

Tezel G, Yang X, Luo C, Cai J, Powell DW.

Invest Ophthalmol Vis Sci. 2012 Jun 28;53(7):4220-33. doi: 10.1167/iovs.11-9101.


Contributions of mass spectrometry-based proteomics to defining cellular mechanisms and diagnostic markers for systemic lupus erythematosus.

Korte EA, Gaffney PM, Powell DW.

Arthritis Res Ther. 2012 Feb 20;14(1):204. doi: 10.1186/ar3701. Review.


Elongin C is a mediator of Notch4 activity in human renal tubule cells.

Cummins TD, Mendenhall MD, Lowry MN, Korte EA, Barati MT, Khundmiri SJ, Salyer SA, Klein JB, Powell DW.

Biochim Biophys Acta. 2011 Dec;1814(12):1748-57. doi: 10.1016/j.bbapap.2011.09.010. Epub 2011 Oct 5.


Neurodegenerative and inflammatory pathway components linked to TNF-α/TNFR1 signaling in the glaucomatous human retina.

Yang X, Luo C, Cai J, Powell DW, Yu D, Kuehn MH, Tezel G.

Invest Ophthalmol Vis Sci. 2011 Oct 31;52(11):8442-54. doi: 10.1167/iovs.11-8152.


Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.

Nanda SK, Venigalla RK, Ordureau A, Patterson-Kane JC, Powell DW, Toth R, Arthur JS, Cohen P.

J Exp Med. 2011 Jun 6;208(6):1215-28. doi: 10.1084/jem.20102177. Epub 2011 May 23.

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