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Items: 1 to 20 of 25


Mutation-Induced Deamidation of Corneal Dystrophy-Related Transforming Growth Factor β-Induced Protein.

Nielsen NS, Juhl DW, Poulsen ET, Lukassen MV, Poulsen EC, Risør MW, Scavenius C, Enghild JJ.

Biochemistry. 2017 Dec 12;56(49):6470-6480. doi: 10.1021/acs.biochem.7b00668. Epub 2017 Nov 22.


Proteomic profiling of TGFBI-null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI-linked corneal dystrophies.

Poulsen ET, Runager K, Nielsen NS, Lukassen MV, Thomsen K, Snider P, Simmons O, Vorum H, Conway SJ, Enghild JJ.

FEBS J. 2018 Jan;285(1):101-114. doi: 10.1111/febs.14321. Epub 2017 Nov 23.


Structural and Functional Implications of Human Transforming Growth Factor β-Induced Protein, TGFBIp, in Corneal Dystrophies.

García-Castellanos R, Nielsen NS, Runager K, Thøgersen IB, Lukassen MV, Poulsen ET, Goulas T, Enghild JJ, Gomis-Rüth FX.

Structure. 2017 Nov 7;25(11):1740-1750.e2. doi: 10.1016/j.str.2017.09.001. Epub 2017 Oct 5.


How glycosaminoglycans promote fibrillation of salmon calcitonin.

Malmos KG, Bjerring M, Jessen CM, Nielsen EHT, Poulsen ET, Christiansen G, Vosegaard T, Skrydstrup T, Enghild JJ, Pedersen JS, Otzen DE.

J Biol Chem. 2017 Sep 22;292(38):15992. doi: 10.1074/jbc.A116.715466. No abstract available.


An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients.

Poulsen ET, Iannuzzi F, Rasmussen HF, Maier TJ, Enghild JJ, Jørgensen AL, Matrone C.

Front Mol Neurosci. 2017 Mar 15;10:59. doi: 10.3389/fnmol.2017.00059. eCollection 2017.


Serum Amyloid P Component (SAP) Interactome in Human Plasma Containing Physiological Calcium Levels.

Poulsen ET, Pedersen KW, Marzeda AM, Enghild JJ.

Biochemistry. 2017 Feb 14;56(6):896-902. doi: 10.1021/acs.biochem.6b01027. Epub 2017 Feb 1.


How Glycosaminoglycans Promote Fibrillation of Salmon Calcitonin.

Malmos KG, Bjerring M, Jessen CM, Nielsen EH, Poulsen ET, Christiansen G, Vosegaard T, Skrydstrup T, Enghild JJ, Pedersen JS, Otzen DE.

J Biol Chem. 2016 Aug 5;291(32):16849-62. doi: 10.1074/jbc.M116.715466. Epub 2016 Jun 8. Erratum in: J Biol Chem. 2017 Sep 22;292(38):15992.


LASIK surgery of granular corneal dystrophy type 2 patients leads to accumulation and differential proteolytic processing of transforming growth factor beta-induced protein (TGFBIp).

Poulsen ET, Nielsen NS, Jensen MM, Nielsen E, Hjortdal J, Kim EK, Enghild JJ.

Proteomics. 2016 Feb;16(3):539-43. doi: 10.1002/pmic.201500287. Epub 2016 Jan 3.


Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy.

Allen EH, Courtney DG, Atkinson SD, Moore JE, Mairs L, Poulsen ET, Schiroli D, Maurizi E, Cole C, Hickerson RP, James J, Murgatroyd H, Smith FJ, MacEwen C, Enghild JJ, Nesbit MA, Leslie Pedrioli DM, McLean WH, Moore CB.

Hum Mol Genet. 2016 Mar 15;25(6):1176-91. doi: 10.1093/hmg/ddw001. Epub 2016 Jan 11.


New Insights to Clathrin and Adaptor Protein 2 for the Design and Development of Therapeutic Strategies.

Poulsen ET, Larsen A, Zollo A, Jørgensen AL, Sanggaard KW, Enghild JJ, Matrone C.

Int J Mol Sci. 2015 Dec 10;16(12):29446-53. doi: 10.3390/ijms161226181.


Protein Composition of TGFBI-R124C- and TGFBI-R555W-Associated Aggregates Suggests Multiple Mechanisms Leading to Lattice and Granular Corneal Dystrophy.

Courtney DG, Poulsen ET, Kennedy S, Moore JE, Atkinson SD, Maurizi E, Nesbit MA, Moore CB, Enghild JJ.

Invest Ophthalmol Vis Sci. 2015 Jul;56(8):4653-61. doi: 10.1167/iovs.15-16922.


The effects of hypochlorous acid and neutrophil proteases on the structure and function of extracellular superoxide dismutase.

Morales K, Olesen MN, Poulsen ET, Larsen UG, Enghild JJ, Petersen SV.

Free Radic Biol Med. 2015 Apr;81:38-46. doi: 10.1016/j.freeradbiomed.2014.12.027. Epub 2015 Jan 9.


Unconditioned commercial embryo culture media contain a large variety of non-declared proteins: a comprehensive proteomics analysis.

Dyrlund TF, Kirkegaard K, Poulsen ET, Sanggaard KW, Hindkjær JJ, Kjems J, Enghild JJ, Ingerslev HJ.

Hum Reprod. 2014 Nov;29(11):2421-30. doi: 10.1093/humrep/deu220. Epub 2014 Aug 27.


Distal renal tubules are deficient in aggresome formation and autophagy upon aldosterone administration.

Cheema MU, Damkier HH, Nielsen J, Poulsen ET, Enghild JJ, Fenton RA, Praetorius J.

PLoS One. 2014 Jul 7;9(7):e101258. doi: 10.1371/journal.pone.0101258. eCollection 2014.


Proteomics of Fuchs' endothelial corneal dystrophy support that the extracellular matrix of Descemet's membrane is disordered.

Poulsen ET, Dyrlund TF, Runager K, Scavenius C, Krogager TP, Højrup P, Thøgersen IB, Sanggaard KW, Vorum H, Hjortdal J, Enghild JJ.

J Proteome Res. 2014 Nov 7;13(11):4659-67. doi: 10.1021/pr500252r. Epub 2014 Jun 27.


The autolysis of human HtrA1 is governed by the redox state of its N-terminal domain.

Risør MW, Poulsen ET, Thomsen LR, Dyrlund TF, Nielsen TA, Nielsen NC, Sanggaard KW, Enghild JJ.

Biochemistry. 2014 Jun 17;53(23):3851-7. doi: 10.1021/bi401633w. Epub 2014 Jun 6.


Coagulation factor XIIIa substrates in human plasma: identification and incorporation into the clot.

Nikolajsen CL, Dyrlund TF, Poulsen ET, Enghild JJ, Scavenius C.

J Biol Chem. 2014 Mar 7;289(10):6526-34. doi: 10.1074/jbc.M113.517904. Epub 2014 Jan 17.


Insight into the Protein Composition of Immunoglobulin Light Chain Deposits of Eyelid, Orbital and Conjunctival Amyloidosis.

Nielsen NS, Poulsen ET, Klintworth GK, Enghild JJ.

J Proteomics Bioinform. 2014;Suppl 8. pii: 002. Epub 2014 Apr 21.


Aldosterone and angiotensin II induce protein aggregation in renal proximal tubules.

Cheema MU, Poulsen ET, Enghild JJ, Hoorn EJ, Fenton RA, Praetorius J.

Physiol Rep. 2013 Sep;1(4):e00064. doi: 10.1002/phy2.64. Epub 2013 Sep 10. Erratum in: Physiol Rep. 2014 Feb 1;2(2):e00251. Hoorn, Ewout [corrected to Hoorn, Ewout J].


Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene.

Poulsen ET, Runager K, Risør MW, Dyrlund TF, Scavenius C, Karring H, Praetorius J, Vorum H, Otzen DE, Klintworth GK, Enghild JJ.

Proteomics Clin Appl. 2014 Apr;8(3-4):168-77. doi: 10.1002/prca.201300058. Epub 2014 Feb 16.

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