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Items: 1 to 20 of 28


Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core.

Lin HK, Boatz JC, Krabbendam IE, Kodali R, Hou Z, Wetzel R, Dolga AM, Poirier MA, van der Wel PCA.

Nat Commun. 2017 May 24;8:15462. doi: 10.1038/ncomms15462.


Twenty years of research and action for the well-being of children.

Poirier MA, Clément MÈ, Dufour S, Moreau J.

Can J Public Health. 2016 Mar 14;106(7 Suppl 2):eS4-6. doi: 10.17269/cjph.106.5102. English, French. No abstract available.


Impact of Inuit customary adoption on behavioral problems in school-age Inuit children.

Decaluwe B, Jacobson SW, Poirier MA, Forget-Dubois N, Jacobson JL, Muckle G.

Am J Orthopsychiatry. 2015 May;85(3):250-8. doi: 10.1037/ort0000071.


Polyglutamine amyloid core boundaries and flanking domain dynamics in huntingtin fragment fibrils determined by solid-state nuclear magnetic resonance.

Hoop CL, Lin HK, Kar K, Hou Z, Poirier MA, Wetzel R, van der Wel PC.

Biochemistry. 2014 Oct 28;53(42):6653-66. doi: 10.1021/bi501010q. Epub 2014 Oct 16.


Root microbiome relates to plant host evolution in maize and other Poaceae.

Bouffaud ML, Poirier MA, Muller D, Moënne-Loccoz Y.

Environ Microbiol. 2014 Sep;16(9):2804-14. doi: 10.1111/1462-2920.12442. Epub 2014 Apr 7.


Identification of novel potentially toxic oligomers formed in vitro from mammalian-derived expanded huntingtin exon-1 protein.

Nucifora LG, Burke KA, Feng X, Arbez N, Zhu S, Miller J, Yang G, Ratovitski T, Delannoy M, Muchowski PJ, Finkbeiner S, Legleiter J, Ross CA, Poirier MA.

J Biol Chem. 2012 May 4;287(19):16017-28. doi: 10.1074/jbc.M111.252577. Epub 2012 Mar 20.


The role of the antimicrobial compound 2,4-diacetylphloroglucinol in the impact of biocontrol Pseudomonas fluorescens F113 on Azospirillum brasilense phytostimulators.

Couillerot O, Combes-Meynet E, Pothier JF, Bellvert F, Challita E, Poirier MA, Rohr R, Comte G, Moënne-Loccoz Y, Prigent-Combaret C.

Microbiology. 2011 Jun;157(Pt 6):1694-705. doi: 10.1099/mic.0.043943-0. Epub 2011 Jan 27.


A compact beta model of huntingtin toxicity.

Zhang QC, Yeh TL, Leyva A, Frank LG, Miller J, Kim YE, Langen R, Finkbeiner S, Amzel ML, Ross CA, Poirier MA.

J Biol Chem. 2011 Mar 11;286(10):8188-96. doi: 10.1074/jbc.M110.192013. Epub 2011 Jan 5.


Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism.

Jiang M, Porat-Shliom Y, Pei Z, Cheng Y, Xiang L, Sommers K, Li Q, Gillardon F, Hengerer B, Berlinicke C, Smith WW, Zack DJ, Poirier MA, Ross CA, Duan W.

J Neurochem. 2010 Jul;114(2):419-29. doi: 10.1111/j.1471-4159.2010.06752.x. Epub 2010 Apr 19.


Assessment of SCAR markers to design real-time PCR primers for rhizosphere quantification of Azospirillum brasilense phytostimulatory inoculants of maize.

Couillerot O, Poirier MA, Prigent-Combaret C, Mavingui P, Caballero-Mellado J, Moënne-Loccoz Y.

J Appl Microbiol. 2010 Aug;109(2):528-38. doi: 10.1111/j.1365-2672.2010.04673.x. Epub 2010 Jan 11.


The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation.

Tam S, Spiess C, Auyeung W, Joachimiak L, Chen B, Poirier MA, Frydman J.

Nat Struct Mol Biol. 2009 Dec;16(12):1279-85. doi: 10.1038/nsmb.1700. Epub 2009 Nov 15.


ATF3 plays a protective role against toxicity by N-terminal fragment of mutant huntingtin in stable PC12 cell line.

Liang Y, Jiang H, Ratovitski T, Jie C, Nakamura M, Hirschhorn RR, Wang X, Smith WW, Hai T, Poirier MA, Ross CA.

Brain Res. 2009 Aug 25;1286:221-9. doi: 10.1016/j.brainres.2009.06.049. Epub 2009 Jun 24.


Preschool-aged children have difficulty constructing and interpreting simple utterances composed of graphic symbols.

Sutton A, Trudeau N, Morford J, Rios M, Poirier MA.

J Child Lang. 2010 Jan;37(1):1-26. doi: 10.1017/S0305000909009477. Epub 2009 Mar 27.


Mutant huntingtin N-terminal fragments of specific size mediate aggregation and toxicity in neuronal cells.

Ratovitski T, Gucek M, Jiang H, Chighladze E, Waldron E, D'Ambola J, Hou Z, Liang Y, Poirier MA, Hirschhorn RR, Graham R, Hayden MR, Cole RN, Ross CA.

J Biol Chem. 2009 Apr 17;284(16):10855-67. doi: 10.1074/jbc.M804813200. Epub 2009 Feb 9.


Persistence of culturable Escherichia coli fecal contaminants in dairy alpine grassland soils.

Texier S, Prigent-Combaret C, Gourdon MH, Poirier MA, Faivre P, Dorioz JM, Poulenard J, Jocteur-Monrozier L, Moënne-Loccoz Y, Trevisan D.

J Environ Qual. 2008 Oct 23;37(6):2299-310. doi: 10.2134/jeq2008.0028. Print 2008 Nov-Dec.


Physical organization and phylogenetic analysis of acdR as leucine-responsive regulator of the 1-aminocyclopropane-1-carboxylate deaminase gene acdS in phytobeneficial Azospirillum lipoferum 4B and other Proteobacteria.

Prigent-Combaret C, Blaha D, Pothier JF, Vial L, Poirier MA, Wisniewski-Dyé F, Moënne-Loccoz Y.

FEMS Microbiol Ecol. 2008 Aug;65(2):202-19. doi: 10.1111/j.1574-6941.2008.00474.x. Epub 2008 Apr 9.


Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin.

Jiang H, Poirier MA, Liang Y, Pei Z, Weiskittel CE, Smith WW, DeFranco DB, Ross CA.

Neurobiol Dis. 2006 Sep;23(3):543-51.


Opinion: What is the role of protein aggregation in neurodegeneration?

Ross CA, Poirier MA.

Nat Rev Mol Cell Biol. 2005 Nov;6(11):891-8. Review.


A structure-based analysis of huntingtin mutant polyglutamine aggregation and toxicity: evidence for a compact beta-sheet structure.

Poirier MA, Jiang H, Ross CA.

Hum Mol Genet. 2005 Mar 15;14(6):765-74. Epub 2005 Feb 2.


Protein aggregation and neurodegenerative disease.

Ross CA, Poirier MA.

Nat Med. 2004 Jul;10 Suppl:S10-7. Review.


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