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Items: 1 to 20 of 29

1.

RNAi as a tool for target discovery in early pharmaceutical research.

Adams R, Steckel M, Nicke B, Pohlenz HD.

Pharmazie. 2016 Jan;71(1):35-42. Review.

PMID:
26867351
2.

Deciphering Seed Sequence Based Off-Target Effects in a Large-Scale RNAi Reporter Screen for E-Cadherin Expression.

Adams R, Nicke B, Pohlenz HD, Sohler F.

PLoS One. 2015 Sep 11;10(9):e0137640. doi: 10.1371/journal.pone.0137640. eCollection 2015.

3.

Mining phenotypes for gene function prediction.

Groth P, Weiss B, Pohlenz HD, Leser U.

BMC Bioinformatics. 2008 Mar 3;9:136. doi: 10.1186/1471-2105-9-136.

4.

PhenomicDB: a new cross-species genotype/phenotype resource.

Groth P, Pavlova N, Kalev I, Tonov S, Georgiev G, Pohlenz HD, Weiss B.

Nucleic Acids Res. 2007 Jan;35(Database issue):D696-9. Epub 2006 Sep 18.

5.

LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain.

Korr D, Toschi L, Donner P, Pohlenz HD, Kreft B, Weiss B.

Cell Signal. 2006 Jun;18(6):910-20. Epub 2005 Oct 21.

PMID:
16243488
6.

The target discovery process.

Egner U, Krätzschmar J, Kreft B, Pohlenz HD, Schneider M.

Chembiochem. 2005 Mar;6(3):468-79. Review.

PMID:
15742383
7.

Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its tamoxifen-resistant subline MaCa 3366/TAM.

Becker M, Sommer A, Krätzschmar JR, Seidel H, Pohlenz HD, Fichtner I.

Mol Cancer Ther. 2005 Jan;4(1):151-68.

8.

PhenomicDB: a multi-species genotype/phenotype database for comparative phenomics.

Kahraman A, Avramov A, Nashev LG, Popov D, Ternes R, Pohlenz HD, Weiss B.

Bioinformatics. 2005 Feb 1;21(3):418-20. Epub 2004 Sep 16.

PMID:
15374875
9.

Shift of syndecan-1 expression from epithelial to stromal cells during progression of solid tumours.

Mennerich D, Vogel A, Klaman I, Dahl E, Lichtner RB, Rosenthal A, Pohlenz HD, Thierauch KH, Sommer A.

Eur J Cancer. 2004 Jun;40(9):1373-82.

PMID:
15177497
10.

Comparison of proteomic and genomic analyses of the human breast cancer cell line T47D and the antiestrogen-resistant derivative T47D-r.

Huber M, Bahr I, Krätzschmar JR, Becker A, Müller EC, Donner P, Pohlenz HD, Schneider MR, Sommer A.

Mol Cell Proteomics. 2004 Jan;3(1):43-55. Epub 2003 Oct 13.

11.

Slow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study.

Clausen T, Huber R, Messerschmidt A, Pohlenz HD, Laber B.

Biochemistry. 1997 Oct 14;36(41):12633-43.

PMID:
9376370
12.

Reaction mechanism of Escherichia coli dihydrodipicolinate synthase investigated by X-ray crystallography and NMR spectroscopy.

Blickling S, Renner C, Laber B, Pohlenz HD, Holak TA, Huber R.

Biochemistry. 1997 Jan 7;36(1):24-33.

PMID:
8993314
13.

Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A.

Clausen T, Huber R, Laber B, Pohlenz HD, Messerschmidt A.

J Mol Biol. 1996 Sep 20;262(2):202-24.

PMID:
8831789
14.

Cloning, purification, and crystallization of Escherichia coli cystathionine beta-lyase.

Laber B, Clausen T, Huber R, Messerschmidt A, Egner U, Müller-Fahrnow A, Pohlenz HD.

FEBS Lett. 1996 Jan 22;379(1):94-6.

15.
16.

Expression of a bacterial gene in transgenic plants confers resistance to the herbicide phenmedipham.

Streber WR, Kutschka U, Thomas F, Pohlenz HD.

Plant Mol Biol. 1994 Sep;25(6):977-87.

PMID:
7919217
17.

Purification and Properties of Cystathionine [gamma]-Synthase from Wheat (Triticum aestivum L.).

Kreft BD, Townsend A, Pohlenz HD, Laber B.

Plant Physiol. 1994 Apr;104(4):1215-1220.

18.

Mechanisms of interaction of Escherichia coli threonine synthase with substrates and inhibitors.

Laber B, Gerbling KP, Harde C, Neff KH, Nordhoff E, Pohlenz HD.

Biochemistry. 1994 Mar 22;33(11):3413-23.

PMID:
7907888
19.

A visible marker for antisense mRNA expression in plants: inhibition of chlorophyll synthesis with a glutamate-1-semialdehyde aminotransferase antisense gene.

Höfgen R, Axelsen KB, Kannangara CG, Schüttke I, Pohlenz HD, Willmitzer L, Grimm B, von Wettstein D.

Proc Natl Acad Sci U S A. 1994 Mar 1;91(5):1726-30.

20.

Inactivation of Escherichia coli threonine synthase by DL-Z-2-amino-5-phosphono-3-pentenoic acid.

Laber B, Lindell SD, Pohlenz HD.

Arch Microbiol. 1994;161(5):400-3.

PMID:
8042902

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