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Items: 1 to 20 of 103

1.

The Role of Xist in X-Chromosome Dosage Compensation.

Sahakyan A, Yang Y, Plath K.

Trends Cell Biol. 2018 Jun 14. pii: S0962-8924(18)30100-4. doi: 10.1016/j.tcb.2018.05.005. [Epub ahead of print] Review.

PMID:
29910081
2.

Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells.

Allison TF, Smith AJH, Anastassiadis K, Sloane-Stanley J, Biga V, Stavish D, Hackland J, Sabri S, Langerman J, Jones M, Plath K, Coca D, Barbaric I, Gokhale P, Andrews PW.

Stem Cell Reports. 2018 Jun 5;10(6):1895-1907. doi: 10.1016/j.stemcr.2018.04.015. Epub 2018 May 17.

3.

Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence.

Ohashi M, Korsakova E, Allen D, Lee P, Fu K, Vargas BS, Cinkornpumin J, Salas C, Park JC, Germanguz I, Langerman J, Chronis C, Kuoy E, Tran S, Xiao X, Pellegrini M, Plath K, Lowry WE.

Stem Cell Reports. 2018 May 8;10(5):1453-1463. doi: 10.1016/j.stemcr.2018.04.001.

4.

X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.

Pasque V, Karnik R, Chronis C, Petrella P, Langerman J, Bonora G, Song J, Vanheer L, Sadhu Dimashkie A, Meissner A, Plath K.

Stem Cell Reports. 2018 May 8;10(5):1537-1550. doi: 10.1016/j.stemcr.2018.03.019. Epub 2018 Apr 19.

5.

High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome.

Keegan A, Plath K, Damoiseaux R.

Methods Mol Biol. 2018;1755:75-87. doi: 10.1007/978-1-4939-7724-6_6.

PMID:
29671264
6.

Correction: Epigenetic resetting of human pluripotency (doi:10.1242/dev.146811).

Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, Sahakyan A, Myers S, Bertone P, Reik W, Plath K, Smith A.

Development. 2018 Apr 18;145(8). pii: dev166397. doi: 10.1242/dev.166397. No abstract available.

7.

Analysis of cardiomyocyte clonal expansion during mouse heart development and injury.

Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, Mikkola HKA, Iruela-Arispe ML, Ardehali R.

Nat Commun. 2018 Feb 21;9(1):754. doi: 10.1038/s41467-018-02891-z.

8.

Regulation of X-chromosome dosage compensation in human: mechanisms and model systems.

Sahakyan A, Plath K, Rougeulle C.

Philos Trans R Soc Lond B Biol Sci. 2017 Nov 5;372(1733). pii: 20160363. doi: 10.1098/rstb.2016.0363. Review.

PMID:
28947660
9.

Epigenetic resetting of human pluripotency.

Guo G, von Meyenn F, Rostovskaya M, Clarke J, Dietmann S, Baker D, Sahakyan A, Myers S, Bertone P, Reik W, Plath K, Smith A.

Development. 2017 Aug 1;144(15):2748-2763. doi: 10.1242/dev.146811. Erratum in: Development. 2018 Apr 18;145(8):.

10.

Cbx3 maintains lineage specificity during neural differentiation.

Huang C, Su T, Xue Y, Cheng C, Lay FD, McKee RA, Li M, Vashisht A, Wohlschlegel J, Novitch BG, Plath K, Kurdistani SK, Carey M.

Genes Dev. 2017 Feb 1;31(3):241-246. doi: 10.1101/gad.292169.116.

11.

Cooperative Binding of Transcription Factors Orchestrates Reprogramming.

Chronis C, Fiziev P, Papp B, Butz S, Bonora G, Sabri S, Ernst J, Plath K.

Cell. 2017 Jan 26;168(3):442-459.e20. doi: 10.1016/j.cell.2016.12.016. Epub 2017 Jan 19.

12.

Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation.

Sahakyan A, Kim R, Chronis C, Sabri S, Bonora G, Theunissen TW, Kuoy E, Langerman J, Clark AT, Jaenisch R, Plath K.

Cell Stem Cell. 2017 Jan 5;20(1):87-101. doi: 10.1016/j.stem.2016.10.006. Epub 2016 Dec 15.

13.

Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation.

Patel S, Bonora G, Sahakyan A, Kim R, Chronis C, Langerman J, Fitz-Gibbon S, Rubbi L, Skelton RJP, Ardehali R, Pellegrini M, Lowry WE, Clark AT, Plath K.

Cell Rep. 2017 Jan 3;18(1):54-67. doi: 10.1016/j.celrep.2016.11.054. Epub 2016 Dec 16.

14.

Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State.

Gu W, Gaeta X, Sahakyan A, Chan AB, Hong CS, Kim R, Braas D, Plath K, Lowry WE, Christofk HR.

Cell Stem Cell. 2016 Oct 6;19(4):476-490. doi: 10.1016/j.stem.2016.08.008. Epub 2016 Sep 8.

15.

Transcriptome Encyclopedia of Early Human Development.

Sahakyan A, Plath K.

Cell. 2016 May 5;165(4):777-9. doi: 10.1016/j.cell.2016.04.042.

16.

The "lnc" between 3D chromatin structure and X chromosome inactivation.

Pandya-Jones A, Plath K.

Semin Cell Dev Biol. 2016 Aug;56:35-47. doi: 10.1016/j.semcdb.2016.04.002. Epub 2016 Apr 6. Review.

17.

Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory.

Pastor WA, Chen D, Liu W, Kim R, Sahakyan A, Lukianchikov A, Plath K, Jacobsen SE, Clark AT.

Cell Stem Cell. 2016 Mar 3;18(3):323-329. doi: 10.1016/j.stem.2016.01.019. Epub 2016 Feb 4.

18.

X chromosome reactivation in reprogramming and in development.

Pasque V, Plath K.

Curr Opin Cell Biol. 2015 Dec;37:75-83. doi: 10.1016/j.ceb.2015.10.006. Epub 2015 Nov 11. Review.

19.

A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase.

Minkovsky A, Sahakyan A, Bonora G, Damoiseaux R, Dimitrova E, Rubbi L, Pellegrini M, Radu CG, Plath K.

Epigenetics Chromatin. 2015 Oct 13;8:42. doi: 10.1186/s13072-015-0034-4. eCollection 2015.

20.

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, Plath K, Guttman M.

Nature. 2015 May 14;521(7551):232-6. doi: 10.1038/nature14443. Epub 2015 Apr 27.

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