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Items: 1 to 20 of 71


In vivo detection of connectivity between cortical and white matter lesions in early MS.

Tillema JM, Weigand SD, Mandrekar J, Shu Y, Lucchinetti CF, Pirko I, Port JD.

Mult Scler. 2016 Oct 3. pii: 1352458516671027.


Neuropilin-1 modulates interferon-γ-stimulated signaling in brain microvascular endothelial cells.

Wang Y, Cao Y, Mangalam AK, Guo Y, LaFrance-Corey RG, Gamez JD, Atanga PA, Clarkson BD, Zhang Y, Wang E, Angom RS, Dutta K, Ji B, Pirko I, Lucchinetti CF, Howe CL, Mukhopadhyay D.

J Cell Sci. 2016 Oct 15;129(20):3911-3921.


Multiple sclerosis masquerading as Alzheimer-type dementia: Clinical, radiological and pathological findings.

Tobin WO, Popescu BF, Lowe V, Pirko I, Parisi JE, Kantarci K, Fields JA, Bruns MB, Boeve BF, Lucchinetti CF.

Mult Scler. 2016 Apr;22(5):698-704. doi: 10.1177/1352458515604382.


Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque.

Frischer JM, Weigand SD, Guo Y, Kale N, Parisi JE, Pirko I, Mandrekar J, Bramow S, Metz I, Brück W, Lassmann H, Lucchinetti CF.

Ann Neurol. 2015 Nov;78(5):710-21. doi: 10.1002/ana.24497.


Poor early relapse recovery affects onset of progressive disease course in multiple sclerosis.

Novotna M, Paz Soldán MM, Abou Zeid N, Kale N, Tutuncu M, Crusan DJ, Atkinson EJ, Siva A, Keegan BM, Pirko I, Pittock SJ, Lucchinetti CF, Noseworthy JH, Weinshenker BG, Rodriguez M, Kantarci OH.

Neurology. 2015 Aug 25;85(8):722-9. doi: 10.1212/WNL.0000000000001856. Erratum in: Neurology. 2015 Oct 13;85(15):1355.


Effective Treatment of Established GL261 Murine Gliomas through Picornavirus Vaccination-Enhanced Tumor Antigen-Specific CD8+ T Cell Responses.

Renner DN, Jin F, Litterman AJ, Balgeman AJ, Hanson LM, Gamez JD, Chae M, Carlson BL, Sarkaria JN, Parney IF, Ohlfest JR, Pirko I, Pavelko KD, Johnson AJ.

PLoS One. 2015 May 1;10(5):e0125565. doi: 10.1371/journal.pone.0125565.


Correlation of Brain Atrophy, Disability, and Spinal Cord Atrophy in a Murine Model of Multiple Sclerosis.

Paz Soldán MM, Raman MR, Gamez JD, Lohrey AK, Chen Y, Pirko I, Johnson AJ.

J Neuroimaging. 2015 Jul-Aug;25(4):595-9. doi: 10.1111/jon.12250.


Relapses and disability accumulation in progressive multiple sclerosis.

Paz Soldán MM, Novotna M, Abou Zeid N, Kale N, Tutuncu M, Crusan DJ, Atkinson EJ, Siva A, Keegan BM, Pirko I, Pittock SJ, Lucchinetti CF, Weinshenker BG, Rodriguez M, Kantarci OH.

Neurology. 2015 Jan 6;84(1):81-8. doi: 10.1212/WNL.0000000000001094.


Perforin competent CD8 T cells are sufficient to cause immune-mediated blood-brain barrier disruption.

Johnson HL, Willenbring RC, Jin F, Manhart WA, LaFrance SJ, Pirko I, Johnson AJ.

PLoS One. 2014 Oct 22;9(10):e111401. doi: 10.1371/journal.pone.0111401.


[cDNA library construction from panicle meristem of finger millet].

Radchuk V, Pirko IaV, Isaenkov SV, Emets AI, Blium IaB.

Tsitol Genet. 2014 Sep-Oct;48(5):3-10. Russian.


MR microscopy of formalin fixed paraffin embedded histology specimens.

Macura S, Mishra PK, Gamez JD, Pirko I.

Magn Reson Med. 2014 Jun;71(6):1989-94. doi: 10.1002/mrm.25225.


Novel immunomodulatory approaches for the management of multiple sclerosis.

Kantarci OH, Pirko I, Rodriguez M.

Clin Pharmacol Ther. 2014 Jan;95(1):32-44. doi: 10.1038/clpt.2013.196. Review.


Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood-brain barrier disruption.

Johnson HL, Hanson LM, Chen Y, Bieber AJ, Buono RJ, Ferraro TN, Pirko I, Johnson AJ.

BMC Genomics. 2013 Oct 3;14:678. doi: 10.1186/1471-2164-14-678.


Pathology of multiple sclerosis: where do we stand?

Popescu BF, Pirko I, Lucchinetti CF.

Continuum (Minneap Minn). 2013 Aug;19(4 Multiple Sclerosis):901-21. doi: 10.1212/01.CON.0000433291.23091.65. Review.


Neuroradiological evaluation of demyelinating disease.

Tillema JM, Pirko I.

Ther Adv Neurol Disord. 2013 Jul;6(4):249-68. doi: 10.1177/1756285613478870.


Theiler's murine encephalomyelitis virus as an experimental model system to study the mechanism of blood-brain barrier disruption.

Johnson HL, Jin F, Pirko I, Johnson AJ.

J Neurovirol. 2014 Apr;20(2):107-12. doi: 10.1007/s13365-013-0187-5. Review.


The thalamus and multiple sclerosis: modern views on pathologic, imaging, and clinical aspects.

Minagar A, Barnett MH, Benedict RH, Pelletier D, Pirko I, Sahraian MA, Frohman E, Zivadinov R.

Neurology. 2013 Jan 8;80(2):210-9. doi: 10.1212/WNL.0b013e31827b910b. Review.


Preserved vascular integrity and enhanced survival following neuropilin-1 inhibition in a mouse model of CD8 T cell-initiated CNS vascular permeability.

Suidan GL, Dickerson JW, Johnson HL, Chan TW, Pavelko KD, Pirko I, Seroogy KB, Johnson AJ.

J Neuroinflammation. 2012 Sep 18;9:218. doi: 10.1186/1742-2094-9-218.


Preclinical (1)H-MRS neurochemical profiling in neurological and psychiatric disorders.

Lee MR, Denic A, Hinton DJ, Mishra PK, Choi DS, Pirko I, Rodriguez M, Macura SI.

Bioanalysis. 2012 Jul;4(14):1787-804. doi: 10.4155/BIO.12.129. Review.


CD8 T cell-initiated blood-brain barrier disruption is independent of neutrophil support.

Johnson HL, Chen Y, Jin F, Hanson LM, Gamez JD, Pirko I, Johnson AJ.

J Immunol. 2012 Aug 15;189(4):1937-45. doi: 10.4049/jimmunol.1200658.

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