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Neprilysin inhibition promotes corneal wound healing.

Genova RM, Meyer KJ, Anderson MG, Harper MM, Pieper AA.

Sci Rep. 2018 Sep 26;8(1):14385. doi: 10.1038/s41598-018-32773-9.


Neuroprotective efficacy of P7C3 compounds in primate hippocampus.

Bauman MD, Schumann CM, Carlson EL, Taylor SL, Vázquez-Rosa E, Cintrón-Pérez CJ, Shin MK, Williams NS, Pieper AA.

Transl Psychiatry. 2018 Sep 26;8(1):202. doi: 10.1038/s41398-018-0244-1.


Neurotherapeutic capacity of P7C3 agents for the treatment of Traumatic Brain Injury.

Blaya MO, Wasserman JM, Pieper AA, Sick TJ, Bramlett HM, Dietrich WD.

Neuropharmacology. 2018 Sep 17. pii: S0028-3908(18)30672-5. doi: 10.1016/j.neuropharm.2018.09.024. [Epub ahead of print] Review.


Combined Blockade of Interleukin-1α and -1β Signaling Protects Mice from Cognitive Dysfunction after Traumatic Brain Injury.

Newell EA, Todd BP, Mahoney J, Pieper AA, Ferguson PJ, Bassuk AG.

eNeuro. 2018 Apr 13;5(2). pii: ENEURO.0385-17.2018. doi: 10.1523/ENEURO.0385-17.2018. eCollection 2018 Mar-Apr.


Ca2+-Binding Protein 1 Regulates Hippocampal-dependent Memory and Synaptic Plasticity.

Yang T, Britt JK, Cintrón-Pérez CJ, Vázquez-Rosa E, Tobin KV, Stalker G, Hardie J, Taugher RJ, Wemmie J, Pieper AA, Lee A.

Neuroscience. 2018 Jun 1;380:90-102. doi: 10.1016/j.neuroscience.2018.04.004. Epub 2018 Apr 14.


Treatment with Uric Acid Reduces Infarct and Improves Neurologic Function in Female Mice After Transient Cerebral Ischemia.

Dhanesha N, Vázquez-Rosa E, Cintrón-Pérez CJ, Thedens D, Kort AJ, Chuong V, Rivera-Dompenciel AM, Chauhan AK, Leira EC, Pieper AA.

J Stroke Cerebrovasc Dis. 2018 May;27(5):1412-1416. doi: 10.1016/j.jstrokecerebrovasdis.2017.12.043. Epub 2018 Feb 15.


Correction: D-cycloserine improves synaptic transmission in an animal mode of Rett syndrome.

Na ES, De Jesús-Cortés H, Martinez-Rivera A, Kabir ZD, Wang J, Ramesh V, Onder Y, Rajadhyaksha AM, Monteggia LM, Pieper AA.

PLoS One. 2018 Jan 25;13(1):e0192057. doi: 10.1371/journal.pone.0192057. eCollection 2018.


(-)-P7C3-S243 Protects a Rat Model of Alzheimer's Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia.

Voorhees JR, Remy MT, Cintrón-Pérez CJ, El Rassi E, Khan MZ, Dutca LM, Yin TC, McDaniel LN, Williams NS, Brat DJ, Pieper AA.

Biol Psychiatry. 2018 Oct 1;84(7):488-498. doi: 10.1016/j.biopsych.2017.10.023. Epub 2017 Nov 6.


Repeated mild traumatic brain injury produces neuroinflammation, anxiety-like behaviour and impaired spatial memory in mice.

Broussard JI, Acion L, De Jesús-Cortés H, Yin T, Britt JK, Salas R, Costa-Mattioli M, Robertson C, Pieper AA, Arciniegas DB, Jorge R.

Brain Inj. 2018;32(1):113-122. doi: 10.1080/02699052.2017.1380228. Epub 2017 Nov 20.


Altered ultrasonic vocalization in neonatal SAPAP3-deficient mice.

Tesdahl NS, King DK, McDaniel LN, Pieper AA.

Neuroreport. 2017 Dec 6;28(17):1115-1118. doi: 10.1097/WNR.0000000000000863.


Beneficial Effects of Delayed P7C3-A20 Treatment After Transient MCAO in Rats.

Loris ZB, Hynton JR, Pieper AA, Dietrich WD.

Transl Stroke Res. 2018 Apr;9(2):146-156. doi: 10.1007/s12975-017-0565-z. Epub 2017 Aug 25.


D-cycloserine improves synaptic transmission in an animal model of Rett syndrome.

Na ES, De Jesús-Cortés H, Martinez-Rivera A, Kabir ZD, Wang J, Ramesh V, Onder Y, Rajadhyaksha AM, Monteggia LM, Pieper AA.

PLoS One. 2017 Aug 16;12(8):e0183026. doi: 10.1371/journal.pone.0183026. eCollection 2017. Erratum in: PLoS One. 2018 Jan 25;13(1):e0192057.


Moving Beyond Serendipity to Mechanism-Driven Psychiatric Therapeutics.

Pieper AA, Baraban JM.

Neurotherapeutics. 2017 Jul;14(3):533-536. doi: 10.1007/s13311-017-0547-6. No abstract available.


Corrigendum to "The neuroprotective compound P7C3-A20 promotes neurogenesis and improves cognitive function after stroke" [Exp. Neurol. 290 (2017) 63-73].

Loris ZB, Pieper AA, Dietrich WD.

Exp Neurol. 2017 Dec;298(Pt A):134. doi: 10.1016/j.expneurol.2017.04.016. Epub 2017 May 13. No abstract available.


Neuronal PAS Domain Proteins 1 and 3 Are Master Regulators of Neuropsychiatric Risk Genes.

Michaelson JJ, Shin MK, Koh JY, Brueggeman L, Zhang A, Katzman A, McDaniel L, Fang M, Pufall M, Pieper AA.

Biol Psychiatry. 2017 Aug 1;82(3):213-223. doi: 10.1016/j.biopsych.2017.03.021. Epub 2017 Apr 6.


Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds.

Voorhees JR, Rohlman DS, Lein PJ, Pieper AA.

Front Neurosci. 2017 Jan 18;10:590. doi: 10.3389/fnins.2016.00590. eCollection 2016. Review.


The neuroprotective compound P7C3-A20 promotes neurogenesis and improves cognitive function after ischemic stroke.

Loris ZB, Pieper AA, Dietrich WD.

Exp Neurol. 2017 Apr;290:63-73. doi: 10.1016/j.expneurol.2017.01.006. Epub 2017 Jan 8. Erratum in: Exp Neurol. 2017 Dec;298(Pt A):134.


Cacna1c: Protecting young hippocampal neurons in the adult brain.

De Jesús-Cortés H, Rajadhyaksha AM, Pieper AA.

Neurogenesis (Austin). 2016 Sep 2;3(1):e1231160. eCollection 2016.


The Eating-Disorder Associated HDAC4A778T Mutation Alters Feeding Behaviors in Female Mice.

Lutter M, Khan MZ, Satio K, Davis KC, Kidder IJ, McDaniel L, Darbro BW, Pieper AA, Cui H.

Biol Psychiatry. 2017 May 1;81(9):770-777. doi: 10.1016/j.biopsych.2016.09.024. Epub 2016 Oct 13.


Acute Axonal Degeneration Drives Development of Cognitive, Motor, and Visual Deficits after Blast-Mediated Traumatic Brain Injury in Mice.

Yin TC, Voorhees JR, Genova RM, Davis KC, Madison AM, Britt JK, Cintrón-Pérez CJ, McDaniel L, Harper MM, Pieper AA.

eNeuro. 2016 Oct 31;3(5). pii: ENEURO.0220-16.2016. eCollection 2016 Sep-Oct.

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