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Items: 5

1.

High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro.

Noguera NI, Pelosi E, Angelini DF, Piredda ML, Guerrera G, Piras E, Battistini L, Massai L, Berardi A, Catalano G, Cicconi L, Castelli G, D'AngiĆ² A, Pasquini L, Graziani G, Fioritoni G, Voso MT, Mastrangelo D, Testa U, Lo-Coco F.

Oncotarget. 2017 May 16;8(20):32550-32565. doi: 10.18632/oncotarget.15925.

2.

Vitamin C in synergism with cisplatin induces cell death in cervical cancer cells through altered redox cycling and p53 upregulation.

Leekha A, Gurjar BS, Tyagi A, Rizvi MA, Verma AK.

J Cancer Res Clin Oncol. 2016 Dec;142(12):2503-2514. Epub 2016 Sep 9.

PMID:
27613187
3.

Redirecting apoptosis to aponecrosis induces selective cytotoxicity to pancreatic cancer cells through increased ROS, decline in ATP levels, and VDAC.

Dinnen RD, Mao Y, Qiu W, Cassai N, Slavkovich VN, Nichols G, Su GH, Brandt-Rauf P, Fine RL.

Mol Cancer Ther. 2013 Dec;12(12):2792-803. doi: 10.1158/1535-7163.MCT-13-0234. Epub 2013 Oct 14.

4.

Enhanced antitumor activity of vitamin C via p53 in cancer cells.

Kim J, Lee SD, Chang B, Jin DH, Jung SI, Park MY, Han Y, Yang Y, Il Kim K, Lim JS, Kang YS, Lee MS.

Free Radic Biol Med. 2012 Oct 15;53(8):1607-15. doi: 10.1016/j.freeradbiomed.2012.07.079. Epub 2012 Aug 4.

PMID:
22892142
5.

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues.

Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, Shacter E, Levine M.

Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13604-9. Epub 2005 Sep 12.

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