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Items: 1 to 20 of 156

1.

Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage.

Vienken H, Mabrouki N, Grabau K, Claas RF, Rudowski A, Schömel N, Pfeilschifter J, Lütjohann D, van Echten-Deckert G, Meyer Zu Heringdorf D.

Sci Rep. 2017 Mar 6;7:43575. doi: 10.1038/srep43575.

2.

Defective IL-23/IL-17 Axis Protects p47phox-/- Mice from Colon Cancer.

Richter C, Herrero San Juan M, Weigmann B, Bergis D, Dauber K, Muders MH, Baretton GB, Pfeilschifter JM, Bonig H, Brenner S, Radeke HH.

Front Immunol. 2017 Jan 27;8:44. doi: 10.3389/fimmu.2017.00044. eCollection 2017 Jan 27.

3.

Anti-Inflammatory Effects of Rosiglitazone in Obesity-Impaired Wound Healing Depend on Adipocyte Differentiation.

Siebert A, Goren I, Pfeilschifter J, Frank S.

PLoS One. 2016 Dec 19;11(12):e0168562. doi: 10.1371/journal.pone.0168562. eCollection 2016 Dec 19.

4.

Interferon-Beta Increases Plasma Ceramides of Specific Chain Length in Multiple Sclerosis Patients, Unlike Fingolimod or Natalizumab.

Ottenlinger FM, Mayer CA, Ferreirós N, Schreiber Y, Schwiebs A, Schmidt KG, Ackermann H, Pfeilschifter JM, Radeke HH.

Front Pharmacol. 2016 Nov 3;7:412. eCollection 2016 Nov 3.

5.

Cytoskeleton-Dependent Transport as a Potential Target for Interfering with Post-transcriptional HuR mRNA Regulons.

Eberhardt W, Badawi A, Biyanee A, Pfeilschifter J.

Front Pharmacol. 2016 Aug 17;7:251. doi: 10.3389/fphar.2016.00251. eCollection 2016 Aug 17. Review.

6.

Sphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential Risks.

Blankenbach KV, Schwalm S, Pfeilschifter J, Meyer Zu Heringdorf D.

Front Pharmacol. 2016 Jun 21;7:167. doi: 10.3389/fphar.2016.00167. eCollection 2016 Jun 21. Review.

7.

Quantitative Persulfide Site Identification (qPerS-SID) Reveals Protein Targets of H2S Releasing Donors in Mammalian Cells.

Longen S, Richter F, Köhler Y, Wittig I, Beck KF, Pfeilschifter J.

Sci Rep. 2016 Jul 14;6:29808. doi: 10.1038/srep29808.

8.

Persistence of HCV in Acutely-Infected Patients Depletes C24-Ceramide and Upregulates Sphingosine and Sphinganine Serum Levels.

Grammatikos G, Dietz J, Ferreiros N, Koch A, Dultz G, Bon D, Karakasiliotis I, Lutz T, Knecht G, Gute P, Herrmann E, Zeuzem S, Mavromara P, Sarrazin C, Pfeilschifter J.

Int J Mol Sci. 2016 Jun 13;17(6). pii: E922. doi: 10.3390/ijms17060922.

9.

Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis.

Coldewey SM, Benetti E, Collino M, Pfeilschifter J, Sponholz C, Bauer M, Huwiler A, Thiemermann C.

Sci Rep. 2016 Jun 9;6:27594. doi: 10.1038/srep27594.

10.

Activation-Induced Cell Death of Dendritic Cells Is Dependent on Sphingosine Kinase 1.

Schwiebs A, Friesen O, Katzy E, Ferreirós N, Pfeilschifter JM, Radeke HH.

Front Pharmacol. 2016 Apr 15;7:94. doi: 10.3389/fphar.2016.00094. eCollection 2016 Apr 15.

11.

Serum sphingolipidomic analyses reveal an upregulation of C16-ceramide and sphingosine-1-phosphate in hepatocellular carcinoma.

Grammatikos G, Schoell N, Ferreirós N, Bon D, Herrmann E, Farnik H, Köberle V, Piiper A, Zeuzem S, Kronenberger B, Waidmann O, Pfeilschifter J.

Oncotarget. 2016 Apr 5;7(14):18095-105. doi: 10.18632/oncotarget.7741.

12.

Increase in Fracture Risk Following Unintentional Weight Loss in Postmenopausal Women: The Global Longitudinal Study of Osteoporosis in Women.

Compston JE, Wyman A, FitzGerald G, Adachi JD, Chapurlat RD, Cooper C, Díez-Pérez A, Gehlbach SH, Greenspan SL, Hooven FH, LaCroix AZ, March L, Netelenbos JC, Nieves JW, Pfeilschifter J, Rossini M, Roux C, Saag KG, Siris ES, Silverman S, Watts NB, Anderson FA Jr.

J Bone Miner Res. 2016 Jul;31(7):1466-72. doi: 10.1002/jbmr.2810.

13.

Though Active on RINm5F Insulinoma Cells and Cultured Pancreatic Islets, Recombinant IL-22 Fails to Modulate Cytotoxicity and Disease in a Protocol of Streptozotocin-Induced Experimental Diabetes.

Berner A, Bachmann M, Bender C, Pfeilschifter J, Christen U, Mühl H.

Front Pharmacol. 2016 Jan 12;6:317. doi: 10.3389/fphar.2015.00317. eCollection 2016 Jan 12.

14.

Erratum: Tristetraprolin regulation of interleukin-22 production.

Härdle L, Bachmann M, Bollmann F, Pautz A, Schmid T, Eberhardt W, Kleinert H, Pfeilschifter J, Mühl H.

Sci Rep. 2015 Dec 18;5:17160. doi: 10.1038/srep17160. No abstract available.

15.

Alterations of the Ceramide Metabolism in the Peri-Infarct Cortex Are Independent of the Sphingomyelinase Pathway and Not Influenced by the Acid Sphingomyelinase Inhibitor Fluoxetine.

Brunkhorst R, Friedlaender F, Ferreirós N, Schwalm S, Koch A, Grammatikos G, Toennes S, Foerch C, Pfeilschifter J, Pfeilschifter W.

Neural Plast. 2015;2015:503079. doi: 10.1155/2015/503079. Epub 2015 Oct 28.

16.

Tristetraprolin regulation of interleukin-22 production.

Härdle L, Bachmann M, Bollmann F, Pautz A, Schmid T, Eberhardt W, Kleinert H, Pfeilschifter J, Mühl H.

Sci Rep. 2015 Oct 21;5:15112. doi: 10.1038/srep15112. Erratum in: Sci Rep. 2015;5:17160.

17.

Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis.

Grammatikos G, Ferreiròs N, Waidmann O, Bon D, Schroeter S, Koch A, Herrmann E, Zeuzem S, Kronenberger B, Pfeilschifter J.

PLoS One. 2015 Sep 18;10(9):e0138130. doi: 10.1371/journal.pone.0138130. eCollection 2015 Sep 18.

18.

Interferon-α curbs production of interleukin-22 by human peripheral blood mononuclear cells exposed to live Borrelia burgdorferi.

Berner A, Bachmann M, Pfeilschifter J, Kraiczy P, Mühl H.

J Cell Mol Med. 2015 Oct;19(10):2507-11. doi: 10.1111/jcmm.12634. Epub 2015 Jul 8.

19.

Simultaneous and dose dependent melanoma cytotoxic and immune stimulatory activity of betulin.

Pfarr K, Danciu C, Arlt O, Neske C, Dehelean C, Pfeilschifter JM, Radeke HH.

PLoS One. 2015 Mar 10;10(3):e0118802. doi: 10.1371/journal.pone.0118802. eCollection 2015 Mar 10.

20.

Application of IL-36 receptor antagonist weakens CCL20 expression and impairs recovery in the late phase of murine acetaminophen-induced liver injury.

Scheiermann P, Bachmann M, Härdle L, Pleli T, Piiper A, Zwissler B, Pfeilschifter J, Mühl H.

Sci Rep. 2015 Feb 17;5:8521. doi: 10.1038/srep08521.

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