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Items: 1 to 20 of 44


Sox2-Deficient Müller Glia Disrupt the Structural and Functional Maturation of the Mammalian Retina.

Bachleda AR, Pevny LH, Weiss ER.

Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1488-99. doi: 10.1167/iovs.15-17994.


Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development.

Dorr KM, Amin NM, Kuchenbrod LM, Labiner H, Charpentier MS, Pevny LH, Wessels A, Conlon FL.

Development. 2015 Jun 1;142(11):2037-47. doi: 10.1242/dev.119107. Epub 2015 May 7.


Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling.

Heavner WE, Andoniadou CL, Pevny LH.

Neural Dev. 2014 Dec 9;9:27. doi: 10.1186/1749-8104-9-27.


Predicting the spatiotemporal dynamics of hair follicle patterns in the developing mouse.

Cheng CW, Niu B, Warren M, Pevny LH, Lovell-Badge R, Hwa T, Cheah KS.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2596-601. doi: 10.1073/pnas.1313083111. Epub 2014 Feb 3.


Sox2 modulates Lef-1 expression during airway submucosal gland development.

Xie W, Lynch TJ, Liu X, Tyler SR, Yu S, Zhou X, Luo M, Kusner DM, Sun X, Yi Y, Zhang Y, Goodheart MJ, Parekh KR, Wells JM, Xue HH, Pevny LH, Engelhardt JF.

Am J Physiol Lung Cell Mol Physiol. 2014 Apr 1;306(7):L645-60. doi: 10.1152/ajplung.00157.2013. Epub 2014 Jan 31.


Oct4 is required ~E7.5 for proliferation in the primitive streak.

DeVeale B, Brokhman I, Mohseni P, Babak T, Yoon C, Lin A, Onishi K, Tomilin A, Pevny L, Zandstra PW, Nagy A, van der Kooy D.

PLoS Genet. 2013 Nov;9(11):e1003957. doi: 10.1371/journal.pgen.1003957. Epub 2013 Nov 14.


Sox2(+) stem/progenitor cells in the adult mouse pituitary support organ homeostasis and have tumor-inducing potential.

Andoniadou CL, Matsushima D, Mousavy Gharavy SN, Signore M, Mackintosh AI, Schaeffer M, Gaston-Massuet C, Mollard P, Jacques TS, Le Tissier P, Dattani MT, Pevny LH, Martinez-Barbera JP.

Cell Stem Cell. 2013 Oct 3;13(4):433-45. doi: 10.1016/j.stem.2013.07.004.


Cleft Palate in a Mouse Model of SOX2 Haploinsufficiency.

Langer L, Sulik K, Pevny L.

Cleft Palate Craniofac J. 2014 Jan;51(1):110-4. doi: 10.1597/12-260. Epub 2013 May 2.


SOX2 maintains the quiescent progenitor cell state of postnatal retinal Muller glia.

Surzenko N, Crowl T, Bachleda A, Langer L, Pevny L.

Development. 2013 Apr;140(7):1445-56. doi: 10.1242/dev.071878. Epub 2013 Mar 5.


Ground-state transcriptional requirements for skin-derived precursors.

Suflita MT, Pfaltzgraff ER, Mundell NA, Pevny LH, Labosky PA.

Stem Cells Dev. 2013 Jun 15;22(12):1779-88. doi: 10.1089/scd.2012.0501. Epub 2013 Feb 27.


Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors.

Clavel C, Grisanti L, Zemla R, Rezza A, Barros R, Sennett R, Mazloom AR, Chung CY, Cai X, Cai CL, Pevny L, Nicolis S, Ma'ayan A, Rendl M.

Dev Cell. 2012 Nov 13;23(5):981-94. doi: 10.1016/j.devcel.2012.10.013.


Eye development and retinogenesis.

Heavner W, Pevny L.

Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12). pii: a008391. doi: 10.1101/cshperspect.a008391. Review.


SOX2 regulates the hypothalamic-pituitary axis at multiple levels.

Jayakody SA, Andoniadou CL, Gaston-Massuet C, Signore M, Cariboni A, Bouloux PM, Le Tissier P, Pevny LH, Dattani MT, Martinez-Barbera JP.

J Clin Invest. 2012 Oct;122(10):3635-46. doi: 10.1172/JCI64311. Epub 2012 Sep 4.


Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis.

Dumitru R, Gama V, Fagan BM, Bower JJ, Swahari V, Pevny LH, Deshmukh M.

Mol Cell. 2012 Jun 8;46(5):573-83. doi: 10.1016/j.molcel.2012.04.002. Epub 2012 May 3.


SOX2 hypomorphism disrupts development of the prechordal floor and optic cup.

Langer L, Taranova O, Sulik K, Pevny L.

Mech Dev. 2012 Mar-Jun;129(1-4):1-12. doi: 10.1016/j.mod.2012.04.001. Epub 2012 Apr 12.


Identification of novel pathways involved in the pathogenesis of human adamantinomatous craniopharyngioma.

Andoniadou CL, Gaston-Massuet C, Reddy R, Schneider RP, Blasco MA, Le Tissier P, Jacques TS, Pevny LH, Dattani MT, Martinez-Barbera JP.

Acta Neuropathol. 2012 Aug;124(2):259-71. doi: 10.1007/s00401-012-0957-9. Epub 2012 Feb 18.


Viral single-strand DNA induces p53-dependent apoptosis in human embryonic stem cells.

Hirsch ML, Fagan BM, Dumitru R, Bower JJ, Yadav S, Porteus MH, Pevny LH, Samulski RJ.

PLoS One. 2011;6(11):e27520. doi: 10.1371/journal.pone.0027520. Epub 2011 Nov 17.


Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.

Engelen E, Akinci U, Bryne JC, Hou J, Gontan C, Moen M, Szumska D, Kockx C, van Ijcken W, Dekkers DH, Demmers J, Rijkers EJ, Bhattacharya S, Philipsen S, Pevny LH, Grosveld FG, Rottier RJ, Lenhard B, Poot RA.

Nat Genet. 2011 Jun;43(6):607-11. doi: 10.1038/ng.825. Epub 2011 May 1.


SOX2 expression levels distinguish between neural progenitor populations of the developing dorsal telencephalon.

Hutton SR, Pevny LH.

Dev Biol. 2011 Apr 1;352(1):40-7. doi: 10.1016/j.ydbio.2011.01.015. Epub 2011 Jan 21.


Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6.

Matsushima D, Heavner W, Pevny LH.

Development. 2011 Feb;138(3):443-54. doi: 10.1242/dev.055178.

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