Format

Send to

Choose Destination

See 1 citation found using an alternative search:

See comment in PubMed Commons below
Lancet. 2012 May 26;379(9830):1997-2007. doi: 10.1016/S0140-6736(12)60198-6. Epub 2012 Apr 17.

Developmental dyslexia.

Author information

1
Department of Psychology, University of Denver, Denver, CO 80208, USA. robin.peterson@du.edu

Abstract

Dyslexia is a neurodevelopmental disorder that is characterised by slow and inaccurate word recognition. Dyslexia has been reported in every culture studied, and mounting evidence draws attention to cross-linguistic similarity in its neurobiological and neurocognitive bases. Much progress has been made across research specialties spanning the behavioural, neuropsychological, neurobiological, and causal levels of analysis in the past 5 years. From a neuropsychological perspective, the phonological theory remains the most compelling, although phonological problems also interact with other cognitive risk factors. Work confirms that, neurobiologically, dyslexia is characterised by dysfunction of the normal left hemisphere language network and also implicates abnormal white matter development. Studies accounting for reading experience demonstrate that many recorded neural differences show causes rather than effects of dyslexia. Six predisposing candidate genes have been identified, and evidence shows gene by environment interaction.

PMID:
22513218
PMCID:
PMC3465717
DOI:
10.1016/S0140-6736(12)60198-6
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center