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Items: 1 to 20 of 34


Cellular characteristics of keratin 19-positive canine hepatocellular tumours explain its aggressive behaviour.

van Sprundel RG, van den Ingh TS, Schotanus BA, van Wolferen ME, Penning LC, Rothuizen J, Spee B.

Vet Rec Open. 2017 Oct 21;4(1):e000212. doi: 10.1136/vetreco-2016-000212. eCollection 2017.


Intestinal Organoids-Current and Future Applications.

Meneses AMC, Schneeberger K, Kruitwagen HS, Penning LC, van Steenbeek FG, Burgener IA, Spee B.

Vet Sci. 2016 Oct 21;3(4). pii: E31. doi: 10.3390/vetsci3040031. Review.


Aberrant hepatic lipid storage and metabolism in canine portosystemic shunts.

Van den Bossche L, Schoonenberg VAC, Burgener IA, Penning LC, Schrall IM, Kruitwagen HS, van Wolferen ME, Grinwis GCM, Kummeling A, Rothuizen J, van Velzen JF, Stathonikos N, Molenaar MR, Helms BJ, Brouwers JFHM, Spee B, van Steenbeek FG.

PLoS One. 2017 Oct 19;12(10):e0186491. doi: 10.1371/journal.pone.0186491. eCollection 2017.


Sensitivity and Specificity of Plasma ALT, ALP, and Bile Acids for Hepatitis in Labrador Retrievers.

Dirksen K, Burgener IA, Rothuizen J, van den Ingh TSGAM, Penning LC, Spee B, Fieten H.

J Vet Intern Med. 2017 Jul;31(4):1017-1027. doi: 10.1111/jvim.14716. Epub 2017 May 23.


Gene expression patterns in the progression of canine copper-associated chronic hepatitis.

Dirksen K, Spee B, Penning LC, van den Ingh TSGAM, Burgener IA, Watson AL, Groot Koerkamp M, Rothuizen J, van Steenbeek FG, Fieten H.

PLoS One. 2017 May 1;12(5):e0176826. doi: 10.1371/journal.pone.0176826. eCollection 2017.


Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis.

Kruitwagen HS, Oosterhoff LA, Vernooij IGWH, Schrall IM, van Wolferen ME, Bannink F, Roesch C, van Uden L, Molenaar MR, Helms JB, Grinwis GCM, Verstegen MMA, van der Laan LJW, Huch M, Geijsen N, Vries RG, Clevers H, Rothuizen J, Schotanus BA, Penning LC, Spee B.

Stem Cell Reports. 2017 Apr 11;8(4):822-830. doi: 10.1016/j.stemcr.2017.02.015. Epub 2017 Mar 23.


Use of Serum MicroRNAs as Biomarker for Hepatobiliary Diseases in Dogs.

Dirksen K, Verzijl T, Grinwis GC, Favier RP, Penning LC, Burgener IA, van der Laan LJ, Fieten H, Spee B.

J Vet Intern Med. 2016 Nov;30(6):1816-1823. doi: 10.1111/jvim.14602. Epub 2016 Nov 11.


The Influence of Pituitary Size on Outcome After Transsphenoidal Hypophysectomy in a Large Cohort of Dogs with Pituitary-Dependent Hypercortisolism.

van Rijn SJ, Galac S, Tryfonidou MA, Hesselink JW, Penning LC, Kooistra HS, Meij BP.

J Vet Intern Med. 2016 Jul;30(4):989-95. doi: 10.1111/jvim.14367. Epub 2016 Jul 18.


Concise Review: Organoids Are a Powerful Tool for the Study of Liver Disease and Personalized Treatment Design in Humans and Animals.

Nantasanti S, de Bruin A, Rothuizen J, Penning LC, Schotanus BA.

Stem Cells Transl Med. 2016 Mar;5(3):325-30. doi: 10.5966/sctm.2015-0152. Epub 2016 Jan 21. Review.


Reference genes for reverse transcription quantitative PCR in canine brain tissue.

Stassen QE, Riemers FM, Reijmerink H, Leegwater PA, Penning LC.

BMC Res Notes. 2015 Dec 9;8:761. doi: 10.1186/s13104-015-1628-4.


Characterization and Comparison of Canine Multipotent Stromal Cells Derived from Liver and Bone Marrow.

Malagola E, Teunissen M, van der Laan LJ, Verstegen MM, Schotanus BA, van Steenbeek FG, Penning LC, van Wolferen ME, Tryfonidou MA, Spee B.

Stem Cells Dev. 2016 Jan 15;25(2):139-50. doi: 10.1089/scd.2015.0125. Epub 2015 Dec 14.


Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids.

Nantasanti S, Spee B, Kruitwagen HS, Chen C, Geijsen N, Oosterhoff LA, van Wolferen ME, Pelaez N, Fieten H, Wubbolts RW, Grinwis GC, Chan J, Huch M, Vries RR, Clevers H, de Bruin A, Rothuizen J, Penning LC, Schotanus BA.

Stem Cell Reports. 2015 Nov 10;5(5):895-907. doi: 10.1016/j.stemcr.2015.09.002. Epub 2015 Oct 8.


The prognostic value of perioperative profiles of ACTH and cortisol for recurrence after transsphenoidal hypophysectomy in dogs with corticotroph adenomas.

van Rijn SJ, Hanson JM, Zierikzee D, Kooistra HS, Penning LC, Tryfonidou MA, Meij BP.

J Vet Intern Med. 2015 May-Jun;29(3):869-76. doi: 10.1111/jvim.12601. Epub 2015 May 8.


Enhanced Wnt/β-catenin and Notch signalling in the activated canine hepatic progenitor cell niche.

Schotanus BA, Kruitwagen HS, van den Ingh TS, van Wolferen ME, Rothuizen J, Penning LC, Spee B.

BMC Vet Res. 2014 Dec 31;10:309. doi: 10.1186/s12917-014-0309-1.


The two main forms of histiocytic sarcoma in the predisposed Flatcoated retriever dog display variation in gene expression.

Boerkamp KM, van Steenbeek FG, Penning LC, Groot Koerkamp MJ, van Leenen D, Vos-Loohuis M, Grinwis GC, Rutteman GR.

PLoS One. 2014 Jun 2;9(6):e98258. doi: 10.1371/journal.pone.0098258. eCollection 2014.


The paracrine feedback loop between vitamin D₃ (1,25(OH)₂D₃) and PTHrP in prehypertrophic chondrocytes.

Bach FC, Rutten K, Hendriks K, Riemers FM, Cornelissen P, de Bruin A, Arkesteijn GJ, Wubbolts R, Horton WA, Penning LC, Tryfonidou MA.

J Cell Physiol. 2014 Dec;229(12):1999-2014. doi: 10.1002/jcp.24658.


Potential regenerative treatment strategies for intervertebral disc degeneration in dogs.

Bach FC, Willems N, Penning LC, Ito K, Meij BP, Tryfonidou MA.

BMC Vet Res. 2014 Jan 4;10:3. doi: 10.1186/1746-6148-10-3. Review.


Gene expression profiling of histiocytic sarcomas in a canine model: the predisposed flatcoated retriever dog.

Boerkamp KM, van der Kooij M, van Steenbeek FG, van Wolferen ME, Groot Koerkamp MJ, van Leenen D, Grinwis GC, Penning LC, Wiemer EA, Rutteman GR.

PLoS One. 2013 Aug 1;8(8):e71094. doi: 10.1371/journal.pone.0071094. Print 2013.


Altered subcellular localization of heat shock protein 90 is associated with impaired expression of the aryl hydrocarbon receptor pathway in dogs.

van Steenbeek FG, Spee B, Penning LC, Kummeling A, van Gils IH, Grinwis GC, Van Leenen D, Holstege FC, Vos-Loohuis M, Rothuizen J, Leegwater PA.

PLoS One. 2013;8(3):e57973. doi: 10.1371/journal.pone.0057973. Epub 2013 Mar 5.


Aberrant gene expression in dogs with portosystemic shunts.

van Steenbeek FG, Van den Bossche L, Grinwis GC, Kummeling A, van Gils IH, Koerkamp MJ, van Leenen D, Holstege FC, Penning LC, Rothuizen J, Leegwater PA, Spee B.

PLoS One. 2013;8(2):e57662. doi: 10.1371/journal.pone.0057662. Epub 2013 Feb 25. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/5cccaae3-f06c-413f-857e-46546e87fce1.

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