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Polyphenol Composition, Antioxidant Activity and Cytotoxicity of Seeds from Two Underexploited Wild Licania Species: L. rigida and L. tomentosa.

Parra Pessoa I, Lopes Neto JJ, Silva de Almeida T, Felipe Farias D, Vieira LR, Lima de Medeiros J, Augusti Boligon A, Peijnenburg A, Castelar I, Fontenele Urano Carvalho A.

Molecules. 2016 Dec 21;21(12). pii: E1755. doi: 10.3390/molecules21121755.


Different responses of Caco-2 and MCF-7 cells to silver nanoparticles are based on highly similar mechanisms of action.

van der Zande M, Undas AK, Kramer E, Monopoli MP, Peters RJ, Garry D, Antunes Fernandes EC, Hendriksen PJ, Marvin HJ, Peijnenburg AA, Bouwmeester H.

Nanotoxicology. 2016 Dec;10(10):1431-1441.


Food safety knowledge on the Bt mutant protein Cry8Ka5 employed in the development of coleopteran-resistant transgenic cotton plants.

Farias DF, Peijnenburg AA, Grossi-de-Sá MF, Carvalho AF.

Bioengineered. 2015;6(6):323-7. doi: 10.1080/21655979.2015.1109755. Review.


The impact of PPARα activation on whole genome gene expression in human precision cut liver slices.

Janssen AW, Betzel B, Stoopen G, Berends FJ, Janssen IM, Peijnenburg AA, Kersten S.

BMC Genomics. 2015 Oct 8;16:760. doi: 10.1186/s12864-015-1969-3.


Inhibition of CXCL12-mediated chemotaxis of Jurkat cells by direct immunotoxicants.

Shao J, Stout I, Volger OL, Hendriksen PJ, van Loveren H, Peijnenburg AA.

Arch Toxicol. 2016 Jul;90(7):1685-94. doi: 10.1007/s00204-015-1585-7.


Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes.

Jetten MJ, Ruiz-Aracama A, Coonen ML, Claessen SM, van Herwijnen MH, Lommen A, van Delft JH, Peijnenburg AA, Kleinjans JC.

Arch Toxicol. 2016 May;90(5):1103-15. doi: 10.1007/s00204-015-1545-2.


Are effects of common ragwort in the Ames test caused by pyrrolizidine alkaloids?

Bovee TF, Helsdingen RJ, Hoogenboom RL, de Nijs MW, Liu X, Vrieling K, Klinkhamer PG, Peijnenburg AA, Mulder PP.

Mutat Res. 2015 Aug;778:1-10. doi: 10.1016/j.mrfmmm.2015.05.006.


Simple and rapid in vitro assay for detecting human thyroid peroxidase disruption.

Jomaa B, de Haan LH, Peijnenburg AA, Bovee TF, Aarts JM, Rietjens IM.

ALTEX. 2015;32(3):191-200. doi:


Protein phosphorylation profiling identifies potential mechanisms for direct immunotoxicity.

Shao J, Stout I, Hendriksen PJ, van Loveren H, Peijnenburg AA, Volger OL.

J Immunotoxicol. 2016;13(1):97-107. doi: 10.3109/1547691X.2015.1016635.


Successful validation of genomic biomarkers for human immunotoxicity in Jurkat T cells in vitro.

Schmeits PC, Shao J, van der Krieken DA, Volger OL, van Loveren H, Peijnenburg AA, Hendriksen PJ.

J Appl Toxicol. 2015 Jul;35(7):831-41. doi: 10.1002/jat.3079.


Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models.

Schmeits PC, Schaap MM, Luijten M, van Someren E, Boorsma A, van Loveren H, Peijnenburg AA, Hendriksen PJ.

Arch Toxicol. 2015 Dec;89(12):2325-37. doi: 10.1007/s00204-014-1365-9.


Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis.

Wang S, Rijk JC, Besselink HT, Houtman R, Peijnenburg AA, Brouwer A, Rietjens IM, Bovee TF.

Toxicol Sci. 2014 Sep;141(1):78-89. doi: 10.1093/toxsci/kfu103.


Developmental toxicity of thyroid-active compounds in a zebrafish embryotoxicity test.

Jomaa B, Hermsen SA, Kessels MY, van den Berg JH, Peijnenburg AA, Aarts JM, Piersma AH, Rietjens IM.

ALTEX. 2014;31(3):303-17. doi:


Sub-chronic toxicity study in rats orally exposed to nanostructured silica.

van der Zande M, Vandebriel RJ, Groot MJ, Kramer E, Herrera Rivera ZE, Rasmussen K, Ossenkoppele JS, Tromp P, Gremmer ER, Peters RJ, Hendriksen PJ, Marvin HJ, Hoogenboom RL, Peijnenburg AA, Bouwmeester H.

Part Fibre Toxicol. 2014 Feb 7;11:8. doi: 10.1186/1743-8977-11-8.


Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices.

Szalowska E, van der Burg B, Man HY, Hendriksen PJ, Peijnenburg AA.

PLoS One. 2014 Jan 29;9(1):e86795. doi: 10.1371/journal.pone.0086795.


Transcriptome-based functional classifiers for direct immunotoxicity.

Shao J, Berger LF, Hendriksen PJ, Peijnenburg AA, van Loveren H, Volger OL.

Arch Toxicol. 2014 Mar;88(3):673-89. doi: 10.1007/s00204-013-1179-1.


DON shares a similar mode of action as the ribotoxic stress inducer anisomycin while TBTO shares ER stress patterns with the ER stress inducer thapsigargin based on comparative gene expression profiling in Jurkat T cells.

Schmeits PC, Katika MR, Peijnenburg AA, van Loveren H, Hendriksen PJ.

Toxicol Lett. 2014 Jan 30;224(3):395-406. doi: 10.1016/j.toxlet.2013.11.005.


Identification of cisplatin-regulated metabolic pathways in pluripotent stem cells.

von Stechow L, Ruiz-Aracama A, van de Water B, Peijnenburg A, Danen E, Lommen A.

PLoS One. 2013 Oct 16;8(10):e76476. doi: 10.1371/journal.pone.0076476.


Towards an integrated in vitro strategy for estrogenicity testing.

Wang S, Aarts JM, de Haan LH, Argyriou D, Peijnenburg AA, Rietjens IM, Bovee TF.

J Appl Toxicol. 2014 Sep;34(9):1031-40. doi: 10.1002/jat.2928.

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