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Items: 1 to 20 of 176

1.

Response to "Tenofovir Disoproxil Fumarate Is Not an Inhibitor of Human Organic Cation Transporter 1".

Minuesa G, Albert C, Pastor-Anglada M, Martinez-Picado J, Koepsell H.

J Pharmacol Exp Ther. 2017 Feb;360(2):343-345. doi: 10.1124/jpet.116.239004. No abstract available.

PMID:
28104832
2.

Novel nuclear hENT2 isoforms regulate cell cycle progression via controlling nucleoside transport and nuclear reservoir.

Grañé-Boladeras N, Spring CM, Hanna WJ, Pastor-Anglada M, Coe IR.

Cell Mol Life Sci. 2016 Dec;73(23):4559-4575. Epub 2016 Jun 6.

PMID:
27271752
3.

Pharmacogenomic analyzis of the responsiveness of gastrointestinal tumor cell lines to drug therapy: A transportome approach.

Grañé-Boladeras N, Pérez-Torras S, Lozano JJ, Romero MR, Mazo A, Marín JJ, Pastor-Anglada M.

Pharmacol Res. 2016 Nov;113(Pt A):364-375. doi: 10.1016/j.phrs.2016.09.007. Epub 2016 Sep 9.

PMID:
27620070
4.

Role of Human Organic Cation Transporter 1 (hOCT1) Polymorphisms in Lamivudine (3TC) Uptake and Drug-Drug Interactions.

Arimany-Nardi C, Minuesa G, Keller T, Erkizia I, Koepsell H, Martinez-Picado J, Pastor-Anglada M.

Front Pharmacol. 2016 Jun 24;7:175. doi: 10.3389/fphar.2016.00175. eCollection 2016.

5.

FLT3 is implicated in cytarabine transport by human equilibrative nucleoside transporter 1 in pediatric acute leukemia.

Català A, Pastor-Anglada M, Caviedes-Cárdenas L, Malatesta R, Rives S, Vega-García N, Camós M, Fernández-Calotti P.

Oncotarget. 2016 Aug 2;7(31):49786-49799. doi: 10.18632/oncotarget.10448.

6.

P-glycoprotein (ABCB1) activity decreases raltegravir disposition in primary CD4+P-gphigh cells and correlates with HIV-1 viral load.

Minuesa G, Arimany-Nardi C, Erkizia I, Cedeño S, Moltó J, Clotet B, Pastor-Anglada M, Martinez-Picado J.

J Antimicrob Chemother. 2016 Oct;71(10):2782-92. doi: 10.1093/jac/dkw215. Epub 2016 Jun 21.

7.

Transportome Profiling Identifies Profound Alterations in Crohn's Disease Partially Restored by Commensal Bacteria.

Pérez-Torras S, Iglesias I, Llopis M, Lozano JJ, Antolín M, Guarner F, Pastor-Anglada M.

J Crohns Colitis. 2016 Jul;10(7):850-9. doi: 10.1093/ecco-jcc/jjw042. Epub 2016 Feb 13.

PMID:
26874350
8.

Reduced Adenosine Uptake and Its Contribution to Signaling that Mediates Profibrotic Activation in Renal Tubular Epithelial Cells: Implication in Diabetic Nephropathy.

Kretschmar C, Oyarzún C, Villablanca C, Jaramillo C, Alarcón S, Perez G, Díaz-Encarnación MM, Pastor-Anglada M, Garrido W, Quezada C, San Martín R.

PLoS One. 2016 Jan 25;11(1):e0147430. doi: 10.1371/journal.pone.0147430. eCollection 2016.

9.

CD69 expression potentially predicts response to bendamustine and its modulation by ibrutinib or idelalisib enhances cytotoxic effect in chronic lymphocytic leukemia.

Montraveta A, Lee-Vergés E, Roldán J, Jiménez L, Cabezas S, Clot G, Pinyol M, Xargay-Torrent S, Rosich L, Arimany-Nardí C, Aymerich M, Villamor N, López-Guillermo A, Pérez-Galán P, Roué G, Pastor-Anglada M, Campo E, López-Guerra M, Colomer D.

Oncotarget. 2016 Feb 2;7(5):5507-20. doi: 10.18632/oncotarget.6685.

10.

Role of SLC22A1 polymorphic variants in drug disposition, therapeutic responses, and drug-drug interactions.

Arimany-Nardi C, Koepsell H, Pastor-Anglada M.

Pharmacogenomics J. 2015 Dec;15(6):473-87. doi: 10.1038/tpj.2015.78. Epub 2015 Nov 3. Review.

PMID:
26526073
11.

Galectin-4 interacts with the drug transporter human concentrative nucleoside transporter 3 to regulate its function.

Fernández-Calotti P, Casulleras O, Antolin M, Guarner F, Pastor-Anglada M.

FASEB J. 2016 Feb;30(2):544-54. doi: 10.1096/fj.15-272773. Epub 2015 Oct 19.

12.

Phosphorylation of RS1 (RSC1A1) Steers Inhibition of Different Exocytotic Pathways for Glucose Transporter SGLT1 and Nucleoside Transporter CNT1, and an RS1-Derived Peptide Inhibits Glucose Absorption.

Veyhl-Wichmann M, Friedrich A, Vernaleken A, Singh S, Kipp H, Gorboulev V, Keller T, Chintalapati C, Pipkorn R, Pastor-Anglada M, Groll J, Koepsell H.

Mol Pharmacol. 2016 Jan;89(1):118-32. doi: 10.1124/mol.115.101162. Epub 2015 Oct 13.

13.

Fluorescent nucleoside derivatives as a tool for the detection of concentrative nucleoside transporter activity using confocal microscopy and flow cytometry.

Claudio-Montero A, Pinilla-Macua I, Fernández-Calotti P, Sancho-Mateo C, Lostao MP, Colomer D, Grandas A, Pastor-Anglada M.

Mol Pharm. 2015 Jun 1;12(6):2158-66. doi: 10.1021/acs.molpharmaceut.5b00142. Epub 2015 May 13.

PMID:
25923048
14.

Ribonucleotide reductase is an effective target to overcome gemcitabine resistance in gemcitabine-resistant pancreatic cancer cells with dual resistant factors.

Minami K, Shinsato Y, Yamamoto M, Takahashi H, Zhang S, Nishizawa Y, Tabata S, Ikeda R, Kawahara K, Tsujikawa K, Chijiiwa K, Yamada K, Akiyama S, Pérez-Torras S, Pastor-Anglada M, Furukawa T, Yasuo T.

J Pharmacol Sci. 2015 Mar;127(3):319-25. doi: 10.1016/j.jphs.2015.01.006. Epub 2015 Feb 7.

15.

Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets.

Pastor-Anglada M, Pérez-Torras S.

Front Pharmacol. 2015 Feb 10;6:13. doi: 10.3389/fphar.2015.00013. eCollection 2015. Review.

16.

Human organic cation transporter 1 (hOCT1) as a mediator of bendamustine uptake and cytotoxicity in chronic lymphocytic leukemia (CLL) cells.

Arimany-Nardi C, Montraveta A, Lee-Vergés E, Puente XS, Koepsell H, Campo E, Colomer D, Pastor-Anglada M.

Pharmacogenomics J. 2015 Aug;15(4):363-71. doi: 10.1038/tpj.2014.77. Epub 2015 Jan 13.

PMID:
25582574
17.

rCNT2 extracellular cysteines, Cys(615) and Cys(649), are important for maturation and sorting to the plasma membrane.

Pinilla-Macua I, Claudio-Montero A, Pastor-Anglada M.

FEBS Lett. 2014 Nov 28;588(23):4382-9. doi: 10.1016/j.febslet.2014.10.006. Epub 2014 Oct 12.

18.

Functional crosstalk between the adenosine transporter CNT3 and purinergic receptors in the biliary epithelia.

Godoy V, Banales JM, Medina JF, Pastor-Anglada M.

J Hepatol. 2014 Dec;61(6):1337-43. doi: 10.1016/j.jhep.2014.06.036. Epub 2014 Jul 14.

PMID:
25034758
19.

Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans.

Wojtal KA, Cee A, Lang S, Götze O, Frühauf H, Geier A, Pastor-Anglada M, Torres-Torronteras J, Martí R, Fried M, Lutz TA, Maggiorini M, Gassmann M, Rogler G, Vavricka SR.

Am J Physiol Gastrointest Liver Physiol. 2014 Oct 1;307(7):G673-88. doi: 10.1152/ajpgi.00353.2013. Epub 2014 Jun 26.

20.

Ribavirin uptake into human hepatocyte HHL5 cells is enhanced by interferon-α via up-regulation of the human concentrative nucleoside transporter (hCNT2).

Pinilla-Macua I, Fernández-Calotti P, Pérez-Del-Pulgar S, Pastor-Anglada M.

Mol Pharm. 2014 Sep 2;11(9):3223-30. doi: 10.1021/mp500263p. Epub 2014 Jul 3.

PMID:
24957263

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