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Items: 1 to 20 of 33

1.

The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A).

Małecki J, Aileni VK, Ho AY, Schwarz J, Moen A, Sørensen V, Nilges BS, Jakobsson ME, Leidel SA, Falnes PØ.

Nucleic Acids Res. 2017 Jan 20. pii: gkx002. doi: 10.1093/nar/gkx002. [Epub ahead of print]

2.

Protein lysine methylation by seven-β-strand methyltransferases.

Falnes PØ, Jakobsson ME, Davydova E, Ho A, Małecki J.

Biochem J. 2016 Jul 15;473(14):1995-2009. doi: 10.1042/BCJ20160117. Review.

PMID:
27407169
3.

Correspondence: On the enzymology and significance of HSPA1 lysine methylation.

Jakobsson ME, Moen A, Falnes PØ.

Nat Commun. 2016 Jun 20;7:11464. doi: 10.1038/ncomms11464. No abstract available.

4.
5.

Lysine Methylation of the Valosin-Containing Protein (VCP) Is Dispensable for Development and Survival of Mice.

Fusser M, Kernstock S, Aileni VK, Egge-Jacobsen W, Falnes PØ, Klungland A.

PLoS One. 2015 Nov 6;10(11):e0141472. doi: 10.1371/journal.pone.0141472.

6.

Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.

Jakobsson ME, Moen A, Davidson B, Falnes PØ.

PLoS One. 2015 Oct 8;10(10):e0140168. doi: 10.1371/journal.pone.0140168.

7.

Saccharomyces cerevisiae Eukaryotic Elongation Factor 1A (eEF1A) Is Methylated at Lys-390 by a METTL21-Like Methyltransferase.

Jakobsson ME, Davydova E, Małecki J, Moen A, Falnes PØ.

PLoS One. 2015 Jun 26;10(6):e0131426. doi: 10.1371/journal.pone.0131426.

8.

Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins.

Zdżalik D, Domańska A, Prorok P, Kosicki K, van den Born E, Falnes PØ, Rizzo CJ, Guengerich FP, Tudek B.

DNA Repair (Amst). 2015 Jun;30:1-10. doi: 10.1016/j.dnarep.2015.02.021.

9.

Human METTL20 is a mitochondrial lysine methyltransferase that targets the β subunit of electron transfer flavoprotein (ETFβ) and modulates its activity.

Małecki J, Ho AY, Moen A, Dahl HA, Falnes PØ.

J Biol Chem. 2015 Jan 2;290(1):423-34. doi: 10.1074/jbc.M114.614115.

10.

Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2).

Davydova E, Ho AY, Malecki J, Moen A, Enserink JM, Jakobsson ME, Loenarz C, Falnes PØ.

J Biol Chem. 2014 Oct 31;289(44):30499-510. doi: 10.1074/jbc.M114.601658.

11.

Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities.

Zdżalik D, Vågbø CB, Kirpekar F, Davydova E, Puścian A, Maciejewska AM, Krokan HE, Klungland A, Tudek B, van den Born E, Falnes PØ.

PLoS One. 2014 Jun 10;9(6):e98729. doi: 10.1371/journal.pone.0098729.

12.

Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.

Jakobsson ME, Moen A, Bousset L, Egge-Jacobsen W, Kernstock S, Melki R, Falnes PØ.

J Biol Chem. 2013 Sep 27;288(39):27752-63. doi: 10.1074/jbc.M113.483248.

13.

Ikbkap/Elp1 deficiency causes male infertility by disrupting meiotic progression.

Lin FJ, Shen L, Jang CW, Falnes PØ, Zhang Y.

PLoS Genet. 2013 May;9(5):e1003516. doi: 10.1371/journal.pgen.1003516.

14.

Human ALKBH4 interacts with proteins associated with transcription.

Bjørnstad LG, Meza TJ, Otterlei M, Olafsrud SM, Meza-Zepeda LA, Falnes PØ.

PLoS One. 2012;7(11):e49045. doi: 10.1371/journal.pone.0049045.

15.

Lysine methylation of VCP by a member of a novel human protein methyltransferase family.

Kernstock S, Davydova E, Jakobsson M, Moen A, Pettersen S, Mælandsmo GM, Egge-Jacobsen W, Falnes PØ.

Nat Commun. 2012;3:1038. doi: 10.1038/ncomms2041.

PMID:
22948820
16.

The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage.

Meza TJ, Moen MN, Vågbø CB, Krokan HE, Klungland A, Grini PE, Falnes PØ.

Nucleic Acids Res. 2012 Aug;40(14):6620-31. doi: 10.1093/nar/gks327.

17.

The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity.

Korvald H, Falnes PØ, Laerdahl JK, Bjørås M, Alseth I.

DNA Repair (Amst). 2012 May 1;11(5):453-62. doi: 10.1016/j.dnarep.2012.01.014.

18.

Roles of Trm9- and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNA.

Leihne V, Kirpekar F, Vågbø CB, van den Born E, Krokan HE, Grini PE, Meza TJ, Falnes PØ.

Nucleic Acids Res. 2011 Sep 1;39(17):7688-701. doi: 10.1093/nar/gkr406.

19.

ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA.

van den Born E, Vågbø CB, Songe-Møller L, Leihne V, Lien GF, Leszczynska G, Malkiewicz A, Krokan HE, Kirpekar F, Klungland A, Falnes PØ.

Nat Commun. 2011 Feb 1;2:172. doi: 10.1038/ncomms1173.

PMID:
21285950
20.

Spectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4.

Bjørnstad LG, Zoppellaro G, Tomter AB, Falnes PØ, Andersson KK.

Biochem J. 2011 Mar 15;434(3):391-8. doi: 10.1042/BJ20101667.

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