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Items: 1 to 20 of 55

1.

Analysis of Single Nucleotide Polymorphisms of STK32B, PPARGC1A and CTNNA3 Gene With Sporadic Parkinson's Disease Susceptibility in Chinese Han Population.

Shi CH, Cheng Y, Tang MB, Liu YT, Yang ZH, Li F, Fan Y, Yang J, Xu YM.

Front Neurol. 2018 May 30;9:387. doi: 10.3389/fneur.2018.00387. eCollection 2018.

2.

Expression of the gene coading for PGC-1α in peripheral blood leukocytes and related gene variants in patients with Parkinson's disease.

Yang XD, Qian YW, Xu SQ, Wan DY, Sun FH, Chen SD, Xiao Q.

Parkinsonism Relat Disord. 2018 Jun;51:30-35. doi: 10.1016/j.parkreldis.2018.02.037. Epub 2018 Feb 23.

PMID:
29496354
3.

Relationship between GWAS-linked three new loci in Essential tremor and risk of Parkinson's disease in Chinese population.

Zhang Y, Zhao Y, Zhou X, Yi M, Li K, Zhou X, Guo J, Xu Q, Yan X, Tang B, Sun Q.

Parkinsonism Relat Disord. 2017 Oct;43:124-126. doi: 10.1016/j.parkreldis.2017.08.014. Epub 2017 Aug 10. No abstract available.

PMID:
28807494
4.

Activation of the ATF2/CREB-PGC-1α pathway by metformin leads to dopaminergic neuroprotection.

Kang H, Khang R, Ham S, Jeong GR, Kim H, Jo M, Lee BD, Lee YI, Jo A, Park C, Kim H, Seo J, Paek SH, Lee YS, Choi JY, Lee Y, Shin JH.

Oncotarget. 2017 Jul 25;8(30):48603-48618. doi: 10.18632/oncotarget.18122.

5.

Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons.

Zheng L, Bernard-Marissal N, Moullan N, D'Amico D, Auwerx J, Moore DJ, Knott G, Aebischer P, Schneider BL.

Hum Mol Genet. 2017 Feb 1;26(3):582-598. doi: 10.1093/hmg/ddw418.

PMID:
28053050
6.

Foxa1 is essential for development and functional integrity of the subthalamic nucleus.

Gasser E, Johannssen HC, Rülicke T, Zeilhofer HU, Stoffel M.

Sci Rep. 2016 Dec 9;6:38611. doi: 10.1038/srep38611.

7.

Genome-wide association study in essential tremor identifies three new loci.

Müller SH, Girard SL, Hopfner F, Merner ND, Bourassa CV, Lorenz D, Clark LN, Tittmann L, Soto-Ortolaza AI, Klebe S, Hallett M, Schneider SA, Hodgkinson CA, Lieb W, Wszolek ZK, Pendziwiat M, Lorenzo-Betancor O, Poewe W, Ortega-Cubero S, Seppi K, Rajput A, Hussl A, Rajput AH, Berg D, Dion PA, Wurster I, Shulman JM, Srulijes K, Haubenberger D, Pastor P, Vilariño-Güell C, Postuma RB, Bernard G, Ladwig KH, Dupré N, Jankovic J, Strauch K, Panisset M, Winkelmann J, Testa CM, Reischl E, Zeuner KE, Ross OA, Arzberger T, Chouinard S, Deuschl G, Louis ED, Kuhlenbäumer G, Rouleau GA.

Brain. 2016 Dec;139(Pt 12):3163-3169. Epub 2016 Oct 20.

8.

Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons.

Jiang H, Kang SU, Zhang S, Karuppagounder S, Xu J, Lee YK, Kang BG, Lee Y, Zhang J, Pletnikova O, Troncoso JC, Pirooznia S, Andrabi SA, Dawson VL, Dawson TM.

eNeuro. 2016 Sep 2;3(4). pii: ENEURO.0183-16.2016. doi: 10.1523/ENEURO.0183-16.2016. eCollection 2016 Jul-Aug.

9.

Delta-9-tetrahydrocannabinol protects against MPP+ toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis.

Zeissler ML, Eastwood J, McCorry K, Hanemann CO, Zajicek JP, Carroll CB.

Oncotarget. 2016 Jul 19;7(29):46603-46614. doi: 10.18632/oncotarget.10314.

10.

The Interaction of Mitochondrial Biogenesis and Fission/Fusion Mediated by PGC-1α Regulates Rotenone-Induced Dopaminergic Neurotoxicity.

Peng K, Yang L, Wang J, Ye F, Dan G, Zhao Y, Cai Y, Cui Z, Ao L, Liu J, Zou Z, Sai Y, Cao J.

Mol Neurobiol. 2017 Jul;54(5):3783-3797. doi: 10.1007/s12035-016-9944-9. Epub 2016 Jun 7.

PMID:
27271125
11.

Detrimental effects of oxidative losses in parkin activity in a model of sporadic Parkinson's disease are attenuated by restoration of PGC1alpha.

Siddiqui A, Rane A, Rajagopalan S, Chinta SJ, Andersen JK.

Neurobiol Dis. 2016 Sep;93:115-20. doi: 10.1016/j.nbd.2016.05.009. Epub 2016 May 13.

PMID:
27185595
12.

Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults.

Hasegawa K, Yasuda T, Shiraishi C, Fujiwara K, Przedborski S, Mochizuki H, Yoshikawa K.

Nat Commun. 2016 Mar 14;7:10943. doi: 10.1038/ncomms10943.

13.

Resveratrol Regulates Mitochondrial Biogenesis and Fission/Fusion to Attenuate Rotenone-Induced Neurotoxicity.

Peng K, Tao Y, Zhang J, Wang J, Ye F, Dan G, Zhao Y, Cai Y, Zhao J, Wu Q, Zou Z, Cao J, Sai Y.

Oxid Med Cell Longev. 2016;2016:6705621. doi: 10.1155/2016/6705621. Epub 2015 Dec 6.

14.

Peroxisome proliferator-activated receptor-γ (PPARγ) agonist is neuroprotective and stimulates PGC-1α expression and CREB phosphorylation in human dopaminergic neurons.

Mäkelä J, Tselykh TV, Kukkonen JP, Eriksson O, Korhonen LT, Lindholm D.

Neuropharmacology. 2016 Mar;102:266-75. doi: 10.1016/j.neuropharm.2015.11.020. Epub 2015 Nov 26.

PMID:
26631533
15.

Does PGC1α/FNDC5/BDNF Elicit the Beneficial Effects of Exercise on Neurodegenerative Disorders?

Jodeiri Farshbaf M, Ghaedi K, Megraw TL, Curtiss J, Shirani Faradonbeh M, Vaziri P, Nasr-Esfahani MH.

Neuromolecular Med. 2016 Mar;18(1):1-15. doi: 10.1007/s12017-015-8370-x. Epub 2015 Nov 26. Review.

PMID:
26611102
16.

Potential Biomarkers of the Earliest Clinical Stages of Parkinson's Disease.

Alieva AKh, Filatova EV, Karabanov AV, Illarioshkin SN, Slominsky PA, Shadrina MI.

Parkinsons Dis. 2015;2015:294396. doi: 10.1155/2015/294396. Epub 2015 Sep 21.

17.

Peripheral Biomarkers of Parkinson's Disease Progression and Pioglitazone Effects.

Simon DK, Simuni T, Elm J, Clark-Matott J, Graebner AK, Baker L, Dunlop SR, Emborg M, Kamp C, Morgan JC, Ross GW, Sharma S, Ravina B; NINDS NET-PD Investigators.

J Parkinsons Dis. 2015;5(4):731-6. doi: 10.3233/JPD-150666.

18.

Mitochondrial Quality Control via the PGC1α-TFEB Signaling Pathway Is Compromised by Parkin Q311X Mutation But Independently Restored by Rapamycin.

Siddiqui A, Bhaumik D, Chinta SJ, Rane A, Rajagopalan S, Lieu CA, Lithgow GJ, Andersen JK.

J Neurosci. 2015 Sep 16;35(37):12833-44. doi: 10.1523/JNEUROSCI.0109-15.2015.

19.

PGC-1α Promoter Methylation in Parkinson's Disease.

Su X, Chu Y, Kordower JH, Li B, Cao H, Huang L, Nishida M, Song L, Wang D, Federoff HJ.

PLoS One. 2015 Aug 28;10(8):e0134087. doi: 10.1371/journal.pone.0134087. eCollection 2015.

20.

Overexpression of PGC-1α Influences Mitochondrial Signal Transduction of Dopaminergic Neurons.

Ye Q, Huang W, Li D, Si E, Wang J, Wang Y, Chen C, Chen X.

Mol Neurobiol. 2016 Aug;53(6):3756-3770. doi: 10.1007/s12035-015-9299-7. Epub 2015 Jul 4.

PMID:
26141122

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