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Items: 1 to 20 of 27


HIV viral kinetics and T cell dynamics in antiretroviral naïve persons starting an integrase strand transfer inhibitor and protease inhibitor regimen.

Karris MY, Jain S, Day TR, Pérez-Santiago J, Goicoechea M, Dubé MP, Sun X, Spina C, Daar ES, Haubrich RH, Morris S; California Collaborative Treatment Group (CCTG) 589 Study Team..

HIV Clin Trials. 2017 Mar;18(2):67-74. doi: 10.1080/15284336.2017.1282578. Epub 2017 Jan 30.


Increased cell-free mitochondrial DNA is a marker of ongoing inflammation and better neurocognitive function in virologically suppressed HIV-infected individuals.

Pérez-Santiago J, De Oliveira MF, Var SR, Day TR, Woods SP, Gianella S, Mehta SR.

J Neurovirol. 2017 Apr;23(2):283-289. doi: 10.1007/s13365-016-0497-5. Epub 2016 Dec 5.


Random shearing as an alternative to digestion for mitochondrial DNA processing in droplet digital PCR.

Vitomirov A, Ramirez-Gaona M, Mehta SR, Pérez-Santiago J.

Mitochondrion. 2017 Jan;32:16-18. doi: 10.1016/j.mito.2016.11.005. Epub 2016 Nov 10.


(1→3)-β-d-Glucan: A Biomarker for Microbial Translocation in Individuals with Acute or Early HIV Infection?

Hoenigl M, Pérez-Santiago J, Nakazawa M, de Oliveira MF, Zhang Y, Finkelman MA, Letendre S, Smith D, Gianella S.

Front Immunol. 2016 Oct 3;7:404. eCollection 2016 Oct 3.


Antiretroviral therapy suppressed participants with low CD4+ T-cell counts segregate according to opposite immunological phenotypes.

Pérez-Santiago J, Ouchi D, Urrea V, Carrillo J, Cabrera C, Villà-Freixa J, Puig J, Paredes R, Negredo E, Clotet B, Massanella M, Blanco J.

AIDS. 2016 Sep 24;30(15):2275-87. doi: 10.1097/QAD.0000000000001205.


(1→3)-β-D-Glucan Levels Correlate With Neurocognitive Functioning in HIV-Infected Persons on Suppressive Antiretroviral Therapy: A Cohort Study.

Hoenigl M, de Oliveira MF, Pérez-Santiago J, Zhang Y, Morris S, McCutchan AJ, Finkelman M, Marcotte TD, Ellis RJ, Gianella S.

Medicine (Baltimore). 2016 Mar;95(11):e3162. doi: 10.1097/MD.0000000000003162.


Replication of Human Herpesviruses Is Associated with Higher HIV DNA Levels during Antiretroviral Therapy Started at Early Phases of HIV Infection.

Gianella S, Anderson CM, Var SR, Oliveira MF, Lada SM, Vargas MV, Massanella M, Little SJ, Richman DD, Strain MC, Pérez-Santiago J, Smith DM.

J Virol. 2016 Mar 28;90(8):3944-52. doi: 10.1128/JVI.02638-15. Print 2016 Apr.


Mitochondrial injury and cognitive function in HIV infection and methamphetamine use.

Var SR, Day TR, Vitomirov A, Smith DM, Soontornniyomkij V, Moore DJ, Achim CL, Mehta SR, Pérez-Santiago J.

AIDS. 2016 Mar 27;30(6):839-48. doi: 10.1097/QAD.0000000000001027.


Corrigendum: Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART.

de Oliveira MF, Murrell B, Pérez-Santiago J, Vargas M, Ellis RJ, Letendre S, Grant I, Smith DM, Woods SP, Gianella S.

Sci Rep. 2016 Jan 19;6:19387. doi: 10.1038/srep19387. No abstract available.


Circulating HIV DNA Correlates With Neurocognitive Impairment in Older HIV-infected Adults on Suppressive ART.

de Oliveira MF, Murrell B, Pérez-Santiago J, Vargas M, Ellis RJ, Letendre S, Grant I, Smith DM, Woods SP, Gianella S.

Sci Rep. 2015 Nov 25;5:17094. doi: 10.1038/srep17094. Erratum in: Sci Rep. 2016;6:19387. Murrel, Ben [corrected to Murrell, Ben].


Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection.

Pérez-Santiago J, Schrier RD, de Oliveira MF, Gianella S, Var SR, Day TR, Ramirez-Gaona M, Suben JD, Murrell B, Massanella M, Cherner M, Smith DM, Ellis RJ, Letendre SL, Mehta SR.

J Neurovirol. 2016 Apr;22(2):191-200. doi: 10.1007/s13365-015-0384-5. Epub 2015 Oct 1.


Subtype associations with HIV-associated neurocognitive disorder in China.

Day TR, Smith DM, Heaton RK, Franklin D, Tilghman MW, Letendre S, Jin H, Wu Z, Shi C, Yu X, Pérez-Santiago J.

J Neurovirol. 2016 Apr;22(2):246-50. doi: 10.1007/s13365-015-0377-4. Epub 2015 Aug 26.


Methamphetamine Use in HIV-infected Individuals Affects T-cell Function and Viral Outcome during Suppressive Antiretroviral Therapy.

Massanella M, Gianella S, Schrier R, Dan JM, Pérez-Santiago J, Oliveira MF, Richman DD, Little SJ, Benson CA, Daar ES, Dube MP, Haubrich RH, Smith DM, Morris SR.

Sci Rep. 2015 Aug 24;5:13179. doi: 10.1038/srep13179.


Cerebrospinal fluid (CSF) CD8+ T-cells that express interferon-gamma contribute to HIV associated neurocognitive disorders (HAND).

Schrier RD, Hong S, Crescini M, Ellis R, Pérez-Santiago J, Spina C, Letendre S; HNRP Group..

PLoS One. 2015 Feb 26;10(2):e0116526. doi: 10.1371/journal.pone.0116526. eCollection 2015 Feb 26.


Correlation of (1→3)-β-D-glucan with other inflammation markers in chronically HIV infected persons on suppressive antiretroviral therapy.

Hoenigl M, de Oliveira MF, Pérez-Santiago J, Zhang Y, Woods SP, Finkelman M, Gianella S.

GMS Infect Dis. 2015;3. pii: Doc3. Epub 2015 Dec 22.


Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection.

Pérez-Santiago J, Gianella S, Massanella M, Spina CA, Karris MY, Var SR, Patel D, Jordan PS, Young JA, Little SJ, Richman DD, Smith DM.

AIDS. 2013 Jul 31;27(12):1921-31.


Differential gene expression in HIV-infected individuals following ART.

Massanella M, Singhania A, Beliakova-Bethell N, Pier R, Lada SM, White CH, Pérez-Santiago J, Blanco J, Richman DD, Little SJ, Woelk CH.

Antiviral Res. 2013 Nov;100(2):420-8. doi: 10.1016/j.antiviral.2013.07.017. Epub 2013 Aug 6.


HIV-1 clade B pol evolution following primary infection.

Hightower GK, May SJ, Pérez-Santiago J, Pacold ME, Wagner GA, Little SJ, Richman DD, Mehta SR, Smith DM, Pond SL.

PLoS One. 2013 Jun 28;8(6):e68188. doi: 10.1371/journal.pone.0068188. Print 2013.


Early but limited effects of raltegravir intensification on CD4 T cell reconstitution in HIV-infected patients with an immunodiscordant response to antiretroviral therapy.

Negredo E, Massanella M, Puertas MC, Buzón MJ, Puig J, Pérez-Alvárez N, Pérez-Santiago J, Bonjoch A, Moltó J, Jou A, Echeverría P, Llibre JM, Martínez-Picado J, Clotet B, Blanco J.

J Antimicrob Chemother. 2013 Oct;68(10):2358-62. doi: 10.1093/jac/dkt183. Epub 2013 May 14.


A combined analysis of microarray gene expression studies of the human prefrontal cortex identifies genes implicated in schizophrenia.

Pérez-Santiago J, Diez-Alarcia R, Callado LF, Zhang JX, Chana G, White CH, Glatt SJ, Tsuang MT, Everall IP, Meana JJ, Woelk CH.

J Psychiatr Res. 2012 Nov;46(11):1464-74. doi: 10.1016/j.jpsychires.2012.08.005. Epub 2012 Sep 3.


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