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Items: 16


Insulin downregulates the expression of the Ca2+-activated nonselective cation channel TRPM5 in pancreatic islets from leptin-deficient mouse models.

Colsoul B, Jacobs G, Philippaert K, Owsianik G, Segal A, Nilius B, Voets T, Schuit F, Vennekens R.

Pflugers Arch. 2014 Mar;466(3):611-21. doi: 10.1007/s00424-013-1389-7. Epub 2013 Nov 13.


TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells.

Zhang ZR, Chu WF, Song B, Gooz M, Zhang JN, Yu CJ, Jiang S, Baldys A, Gooz P, Steele S, Owsianik G, Nilius B, Komlosi P, Bell PD.

PLoS One. 2013 Aug 16;8(8):e73424. doi: 10.1371/journal.pone.0073424. eCollection 2013.


TRPV3: time to decipher a poorly understood family member!

Nilius B, Bíró T, Owsianik G.

J Physiol. 2014 Jan 15;592(2):295-304. doi: 10.1113/jphysiol.2013.255968. Epub 2013 Jul 8. Review.


The transient receptor potential family of ion channels.

Nilius B, Owsianik G.

Genome Biol. 2011;12(3):218. doi: 10.1186/gb-2011-12-3-218. Epub 2011 Mar 17. Review.


Irritating channels: the case of TRPA1.

Nilius B, Prenen J, Owsianik G.

J Physiol. 2011 Apr 1;589(Pt 7):1543-9. doi: 10.1113/jphysiol.2010.200717. Epub 2010 Nov 15. Review.


Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.

Everaerts W, Zhen X, Ghosh D, Vriens J, Gevaert T, Gilbert JP, Hayward NJ, McNamara CR, Xue F, Moran MM, Strassmaier T, Uykal E, Owsianik G, Vennekens R, De Ridder D, Nilius B, Fanger CM, Voets T.

Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19084-9. doi: 10.1073/pnas.1005333107. Epub 2010 Oct 18.


TRP channels in neurogastroenterology: opportunities for therapeutic intervention.

Boesmans W, Owsianik G, Tack J, Voets T, Vanden Berghe P.

Br J Pharmacol. 2011 Jan;162(1):18-37. doi: 10.1111/j.1476-5381.2010.01009.x. Review.


Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice.

Colsoul B, Schraenen A, Lemaire K, Quintens R, Van Lommel L, Segal A, Owsianik G, Talavera K, Voets T, Margolskee RF, Kokrashvili Z, Gilon P, Nilius B, Schuit FC, Vennekens R.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5208-13. doi: 10.1073/pnas.0913107107. Epub 2010 Mar 1.


Functional characterization of transient receptor potential channels in mouse urothelial cells.

Everaerts W, Vriens J, Owsianik G, Appendino G, Voets T, De Ridder D, Nilius B.

Am J Physiol Renal Physiol. 2010 Mar;298(3):F692-701. doi: 10.1152/ajprenal.00599.2009. Epub 2009 Dec 16.


Transient receptor potential channels meet phosphoinositides.

Nilius B, Owsianik G, Voets T.

EMBO J. 2008 Nov 5;27(21):2809-16. doi: 10.1038/emboj.2008.217. Epub 2008 Oct 16. Review.


Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia.

Rock MJ, Prenen J, Funari VA, Funari TL, Merriman B, Nelson SF, Lachman RS, Wilcox WR, Reyno S, Quadrelli R, Vaglio A, Owsianik G, Janssens A, Voets T, Ikegawa S, Nagai T, Rimoin DL, Nilius B, Cohn DH.

Nat Genet. 2008 Aug;40(8):999-1003. doi: 10.1038/ng.166. Epub 2008 Jun 29.


Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding.

Gevaert T, Vriens J, Segal A, Everaerts W, Roskams T, Talavera K, Owsianik G, Liedtke W, Daelemans D, Dewachter I, Van Leuven F, Voets T, De Ridder D, Nilius B.

J Clin Invest. 2007 Nov;117(11):3453-62.


The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate.

Nilius B, Mahieu F, Prenen J, Janssens A, Owsianik G, Vennekens R, Voets T.

EMBO J. 2006 Feb 8;25(3):467-78. Epub 2006 Jan 19.


Gating of TRP channels: a voltage connection?

Nilius B, Talavera K, Owsianik G, Prenen J, Droogmans G, Voets T.

J Physiol. 2005 Aug 15;567(Pt 1):35-44. Epub 2005 May 5. Review.


Transcriptional activation of metalloid tolerance genes in Saccharomyces cerevisiae requires the AP-1-like proteins Yap1p and Yap8p.

Wysocki R, Fortier PK, Maciaszczyk E, Thorsen M, Leduc A, Odhagen A, Owsianik G, Ulaszewski S, Ramotar D, Tamás MJ.

Mol Biol Cell. 2004 May;15(5):2049-60. Epub 2004 Feb 20.

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