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Items: 1 to 20 of 135

1.

Discovery and characterization of small molecule Rac1 inhibitors.

Arnst JL, Hein AL, Taylor MA, Palermo NY, Contreras JI, Sonawane YA, Wahl AO, Ouellette MM, Natarajan A, Yan Y.

Oncotarget. 2017 May 23;8(21):34586-34600. doi: 10.18632/oncotarget.16656.

PMID:
28410221
2.

Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms.

Fernandez-Prada C, Vincent IM, Brotherton MC, Roberts M, Roy G, Rivas L, Leprohon P, Smith TK, Ouellette M.

PLoS Negl Trop Dis. 2016 Dec 2;10(12):e0005171. doi: 10.1371/journal.pntd.0005171. eCollection 2016 Dec.

PMID:
27911896
3.

Rac1/RhoA antagonism defines cell-to-cell heterogeneity during epidermal morphogenesis in nematodes.

Martin E, Ouellette MH, Jenna S.

J Cell Biol. 2016 Nov 21;215(4):483-498. Epub 2016 Nov 7.

PMID:
27821782
4.

Plasticity of the Leishmania genome leading to gene copy number variations and drug resistance.

Laffitte MN, Leprohon P, Papadopoulou B, Ouellette M.

F1000Res. 2016 Sep 20;5:2350. doi: 10.12688/f1000research.9218.1. eCollection 2016. Review.

PMID:
27703673
5.

Chromosomal Translocations in the Parasite Leishmania by a MRE11/RAD50-Independent Microhomology-Mediated End Joining Mechanism.

Laffitte MC, Leprohon P, Hainse M, Légaré D, Masson JY, Ouellette M.

PLoS Genet. 2016 Jun 17;12(6):e1006117. doi: 10.1371/journal.pgen.1006117. eCollection 2016 Jun.

PMID:
27314941
6.

RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment.

Hein AL, Post CM, Sheinin YM, Lakshmanan I, Natarajan A, Enke CA, Batra SK, Ouellette MM, Yan Y.

Oncogene. 2016 Dec 8;35(49):6319-6329. doi: 10.1038/onc.2016.163. Epub 2016 May 16.

PMID:
27181206
7.

Cos-Seq for high-throughput identification of drug target and resistance mechanisms in the protozoan parasite Leishmania.

Gazanion É, Fernández-Prada C, Papadopoulou B, Leprohon P, Ouellette M.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):E3012-21. doi: 10.1073/pnas.1520693113. Epub 2016 May 9.

PMID:
27162331
8.

PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling.

Hein AL, Seshacharyulu P, Rachagani S, Sheinin YM, Ouellette MM, Ponnusamy MP, Mumby MC, Batra SK, Yan Y.

Cancer Res. 2016 Apr 15;76(8):2243-2253. doi: 10.1158/0008-5472.CAN-15-2119. Epub 2016 Feb 18.

PMID:
26893480
9.

CXCR2 signaling regulates KRAS(G¹²D)-induced autocrine growth of pancreatic cancer.

Purohit A, Varney M, Rachagani S, Ouellette MM, Batra SK, Singh RK.

Oncotarget. 2016 Feb 9;7(6):7280-96. doi: 10.18632/oncotarget.6906.

PMID:
26771140
10.

Overexpression of PD2 leads to increased tumorigenicity and metastasis in pancreatic ductal adenocarcinoma.

Vaz AP, Deb S, Rachagani S, Dey P, Muniyan S, Lakshmanan I, Karmakar S, Smith L, Johansson S, Lele S, Ouellette M, Ponnusamy MP, Batra SK.

Oncotarget. 2016 Jan 19;7(3):3317-31. doi: 10.18632/oncotarget.6580.

PMID:
26689992
11.

A genomic approach to understand interactions between Streptococcus pneumoniae and its bacteriophages.

Leprohon P, Gingras H, Ouennane S, Moineau S, Ouellette M.

BMC Genomics. 2015 Nov 18;16:972. doi: 10.1186/s12864-015-2134-8.

PMID:
26582495
12.

Mitochondrial Proteomics of Antimony and Miltefosine Resistant Leishmania infantum.

Vincent IM, Racine G, Légaré D, Ouellette M.

Proteomes. 2015 Oct 21;3(4):328-346. doi: 10.3390/proteomes3040328.

PMID:
28248274
13.

On Lactococcus lactis UL719 competitivity and nisin (Nisaplin(®)) capacity to inhibit Clostridium difficile in a model of human colon.

Le Lay C, Fernandez B, Hammami R, Ouellette M, Fliss I.

Front Microbiol. 2015 Sep 25;6:1020. doi: 10.3389/fmicb.2015.01020. eCollection 2015.

PMID:
26441942
14.

Rac1 GTPase in pancreatic cancer.

Yan Y, Ouellette MM.

Aging (Albany NY). 2015 Sep;7(9):609-10. No abstract available.

PMID:
26420819
15.

Next Generation Vaccine Biomarkers workshop October 30-31, 2014--Ottawa, Canada.

Twine SM, Fulton KM, Spika J, Ouellette M, Raven JF, Conlan JW, Krishnan L, Barreto L, Richards JC.

Hum Vaccin Immunother. 2015;11(12):2923-30. doi: 10.1080/21645515.2015.1083663.

PMID:
26383909
16.

The initial state of the human gut microbiome determines its reshaping by antibiotics.

Raymond F, Ouameur AA, Déraspe M, Iqbal N, Gingras H, Dridi B, Leprohon P, Plante PL, Giroux R, Bérubé È, Frenette J, Boudreau DK, Simard JL, Chabot I, Domingo MC, Trottier S, Boissinot M, Huletsky A, Roy PH, Ouellette M, Bergeron MG, Corbeil J.

ISME J. 2016 Mar;10(3):707-20. doi: 10.1038/ismej.2015.148. Epub 2015 Sep 11.

PMID:
26359913
17.

Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae.

Dridi B, Lupien A, Bergeron MG, Leprohon P, Ouellette M.

Antimicrob Agents Chemother. 2015 Sep;59(9):5420-6. doi: 10.1128/AAC.00316-15. Epub 2015 Jun 22.

PMID:
26100702
18.

Drug resistance analysis by next generation sequencing in Leishmania.

Leprohon P, Fernandez-Prada C, Gazanion É, Monte-Neto R, Ouellette M.

Int J Parasitol Drugs Drug Resist. 2014 Sep 22;5(1):26-35. doi: 10.1016/j.ijpddr.2014.09.005. eCollection 2015 Apr. Review.

PMID:
25941624
19.

The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs.

Choi KH, Lakamp-Hawley AS, Kolar C, Yan Y, Borgstahl GEO, Ouellette MM.

Biochimie. 2015 Aug;115:17-27. doi: 10.1016/j.biochi.2015.04.015. Epub 2015 Apr 28.

PMID:
25934589
20.

Genome-wide DNA methylation analysis of Haloferax volcanii H26 and identification of DNA methyltransferase related PD-(D/E)XK nuclease family protein HVO_A0006.

Ouellette M, Jackson L, Chimileski S, Papke RT.

Front Microbiol. 2015 Apr 8;6:251. doi: 10.3389/fmicb.2015.00251. eCollection 2015.

PMID:
25904898

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