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Items: 1 to 20 of 32


Association between osteocalcin and cognitive performance in healthy older adults.

Bradburn S, McPhee JS, Bagley L, Sipila S, Stenroth L, Narici MV, Pääsuke M, Gapeyeva H, Osborne G, Sassano L, Meskers CG, Maier AB, Hogrel JY, Barnouin Y, Butler-Browne G, Murgatroyd C.

Age Ageing. 2016 Nov;45(6):844-849. Epub 2016 Aug 11.


UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

Hjerpe R, Bett JS, Keuss MJ, Solovyova A, McWilliams TG, Johnson C, Sahu I, Varghese J, Wood N, Wightman M, Osborne G, Bates GP, Glickman MH, Trost M, Knebel A, Marchesi F, Kurz T.

Cell. 2016 Aug 11;166(4):935-49. doi: 10.1016/j.cell.2016.07.001. Epub 2016 Jul 28.


Targeting membrane proteins for antibody discovery using phage display.

Jones ML, Alfaleh MA, Kumble S, Zhang S, Osborne GW, Yeh M, Arora N, Hou JJ, Howard CB, Chin DY, Mahler SM.

Sci Rep. 2016 May 18;6:26240. doi: 10.1038/srep26240.


A retrospective review of cancer treatments and outcomes among Inuit referred from Nunavut, Canada.

Asmis TR, Febbraro M, Alvarez GG, Spaans JN, Ruta M, Lalany A, Osborne G, Goss GD.

Curr Oncol. 2015 Aug;22(4):246-51. doi: 10.3747/co.22.2421.


Screening for Chemical Contributions to Breast Cancer Risk: A Case Study for Chemical Safety Evaluation.

Schwarzman MR, Ackerman JM, Dairkee SH, Fenton SE, Johnson D, Navarro KM, Osborne G, Rudel RA, Solomon GM, Zeise L, Janssen S.

Environ Health Perspect. 2015 Dec;123(12):1255-64. doi: 10.1289/ehp.1408337. Epub 2015 Jun 2. Review.


Reducing Igf-1r levels leads to paradoxical and sexually dimorphic effects in HD mice.

Corrochano S, Renna M, Osborne G, Carter S, Stewart M, May J, Bates GP, Brown SD, Rubinsztein DC, Acevedo-Arozena A.

PLoS One. 2014 Aug 20;9(8):e105595. doi: 10.1371/journal.pone.0105595. eCollection 2014.


Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.

Mielcarek M, Inuabasi L, Bondulich MK, Muller T, Osborne GF, Franklin SA, Smith DL, Neueder A, Rosinski J, Rattray I, Protti A, Bates GP.

PLoS Genet. 2014 Aug 7;10(8):e1004550. doi: 10.1371/journal.pgen.1004550. eCollection 2014 Aug.


Taima (stop) TB: the impact of a multifaceted TB awareness and door-to-door campaign in residential areas of high risk for TB in Iqaluit, Nunavut.

Alvarez GG, VanDyk DD, Aaron SD, Cameron DW, Davies N, Stephen N, Mallick R, Momoli F, Moreau K, Obed N, Baikie M, Osborne G.

PLoS One. 2014 Jul 17;9(7):e100975. doi: 10.1371/journal.pone.0100975. eCollection 2014.


Genetic deletion of transglutaminase 2 does not rescue the phenotypic deficits observed in R6/2 and zQ175 mouse models of Huntington's disease.

Menalled LB, Kudwa AE, Oakeshott S, Farrar A, Paterson N, Filippov I, Miller S, Kwan M, Olsen M, Beltran J, Torello J, Fitzpatrick J, Mushlin R, Cox K, McConnell K, Mazzella M, He D, Osborne GF, Al-Nackkash R, Bates GP, Tuunanen P, Lehtimaki K, Brunner D, Ghavami A, Ramboz S, Park L, Macdonald D, Munoz-Sanjuan I, Howland D.

PLoS One. 2014 Jun 23;9(6):e99520. doi: 10.1371/journal.pone.0099520. eCollection 2014.


HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration.

Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, Inuabasi L, Osborne GF, Wadel K, Touller C, Butler R, Robertson J, Franklin SA, Smith DL, Park L, Marks PA, Wanker EE, Olson EN, Luthi-Carter R, van der Putten H, Beaumont V, Bates GP.

PLoS Biol. 2013 Nov;11(11):e1001717. doi: 10.1371/journal.pbio.1001717. Epub 2013 Nov 26.


HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo.

Mielcarek M, Seredenina T, Stokes MP, Osborne GF, Landles C, Inuabasi L, Franklin SA, Silva JC, Luthi-Carter R, Beaumont V, Bates GP.

PLoS One. 2013 Nov 22;8(11):e80849. doi: 10.1371/journal.pone.0080849. eCollection 2013.


Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment.

Hutchings CJ, Cseke G, Osborne G, Woolard J, Zhukov A, Koglin M, Jazayeri A, Pandya-Pathak J, Langmead CJ, Hill SJ, Weir M, Marshall FH.

MAbs. 2014 Jan-Feb;6(1):246-61.


Glioma surgical aspirate: a viable source of tumor tissue for experimental research.

Day BW, Stringer BW, Wilson J, Jeffree RL, Jamieson PR, Ensbey KS, Bruce ZC, Inglis P, Allan S, Winter C, Tollesson G, Campbell S, Lucas P, Findlay W, Kadrian D, Johnson D, Robertson T, Johns TG, Bartlett PF, Osborne GW, Boyd AW.

Cancers (Basel). 2013 Apr 3;5(2):357-71. doi: 10.3390/cancers5020357.


Collaborating toward improving food security in Nunavut.

Wakegijig J, Osborne G, Statham S, Issaluk MD.

Int J Circumpolar Health. 2013 Aug 5;72. doi: 10.3402/ijch.v72i0.21201. eCollection 2013.


Analysis of mitochondrial function and localisation during human embryonic stem cell differentiation in vitro.

Prowse AB, Chong F, Elliott DA, Elefanty AG, Stanley EG, Gray PP, Munro TP, Osborne GW.

PLoS One. 2012;7(12):e52214. doi: 10.1371/journal.pone.0052214. Epub 2012 Dec 19.


Causes and risk factors for infant mortality in Nunavut, Canada 1999-2011.

Collins SA, Surmala P, Osborne G, Greenberg C, Bathory LW, Edmunds-Potvin S, Arbour L.

BMC Pediatr. 2012 Dec 12;12:190. doi: 10.1186/1471-2431-12-190.


Sources of food affect dietary adequacy of Inuit women of childbearing age in Arctic Canada.

Schaefer SE, Erber E, Trzaskos JP, Roache C, Osborne G, Sharma S.

J Health Popul Nutr. 2011 Oct;29(5):454-64.


Purification of immature neuronal cells from neural stem cell progeny.

Azari H, Osborne GW, Yasuda T, Golmohammadi MG, Rahman M, Deleyrolle LP, Esfandiari E, Adams DJ, Scheffler B, Steindler DA, Reynolds BA.

PLoS One. 2011;6(6):e20941. doi: 10.1371/journal.pone.0020941. Epub 2011 Jun 3.


Discovery of a Selective S1P1 Receptor Agonist Efficacious at Low Oral Dose and Devoid of Effects on Heart Rate.

Demont EH, Andrews BI, Bit RA, Campbell CA, Cooke JW, Deeks N, Desai S, Dowell SJ, Gaskin P, Gray JR, Haynes A, Holmes DS, Kumar U, Morse MA, Osborne GJ, Panchal T, Patel B, Perboni A, Taylor S, Watson R, Witherington J, Willis R.

ACS Med Chem Lett. 2011 Mar 24;2(6):444-9. doi: 10.1021/ml2000214. eCollection 2011 Jun 9.


Evidence for label-retaining tumour-initiating cells in human glioblastoma.

Deleyrolle LP, Harding A, Cato K, Siebzehnrubl FA, Rahman M, Azari H, Olson S, Gabrielli B, Osborne G, Vescovi A, Reynolds BA.

Brain. 2011 May;134(Pt 5):1331-43. doi: 10.1093/brain/awr081. Epub 2011 Apr 22.

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