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  • Showing results for rorsman p. Search instead for Orsman P (1 item)
1.

Ca2+ channel clustering with insulin-containing granules is disturbed in type 2 diabetes.

Gandasi NR, Yin P, Riz M, Chibalina MV, Cortese G, Lund PE, Matveev V, Rorsman P, Sherman A, Pedersen MG, Barg S.

J Clin Invest. 2017 May 8. pii: 88491. doi: 10.1172/JCI88491. [Epub ahead of print]

2.

Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.

Philippaert K, Pironet A, Mesuere M, Sones W, Vermeiren L, Kerselaers S, Pinto S, Segal A, Antoine N, Gysemans C, Laureys J, Lemaire K, Gilon P, Cuypers E, Tytgat J, Mathieu C, Schuit F, Rorsman P, Talavera K, Voets T, Vennekens R.

Nat Commun. 2017 Mar 31;8:14733. doi: 10.1038/ncomms14733.

3.

Functional identification of islet cell types by electrophysiological fingerprinting.

Briant LJ, Zhang Q, Vergari E, Kellard JA, Rodriguez B, Ashcroft FM, Rorsman P.

J R Soc Interface. 2017 Mar;14(128). pii: 20160999. doi: 10.1098/rsif.2016.0999.

4.

Anti-diabetic action of all-trans retinoic acid and the orphan G protein coupled receptor GPRC5C in pancreatic β-cells.

Amisten S, Mohammad Al-Amily I, Soni A, Hawkes R, Atanes P, Persaud SJ, Rorsman P, Salehi A.

Endocr J. 2017 Mar 31;64(3):325-338. doi: 10.1507/endocrj.EJ16-0338. Epub 2017 Feb 22.

5.

A role of PLC/PKC-dependent pathway in GLP-1-stimulated insulin secretion.

Shigeto M, Cha CY, Rorsman P, Kaku K.

J Mol Med (Berl). 2017 Apr;95(4):361-368. doi: 10.1007/s00109-017-1508-6. Epub 2017 Jan 17. Review.

PMID:
28097390
6.

Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells.

Brereton MF, Rohm M, Shimomura K, Holland C, Tornovsky-Babeay S, Dadon D, Iberl M, Chibalina MV, Lee S, Glaser B, Dor Y, Rorsman P, Clark A, Ashcroft FM.

Nat Commun. 2016 Nov 24;7:13496. doi: 10.1038/ncomms13496.

7.

Key Matrix Proteins Within the Pancreatic Islet Basement Membrane Are Differentially Digested During Human Islet Isolation.

Cross SE, Vaughan RH, Willcox AJ, McBride AJ, Abraham AA, Han B, Johnson JD, Maillard E, Bateman PA, Ramracheya RD, Rorsman P, Kadler KE, Dunne MJ, Hughes SJ, Johnson PR.

Am J Transplant. 2017 Feb;17(2):451-461. doi: 10.1111/ajt.13975. Epub 2016 Sep 6.

PMID:
27456745
8.

Angular Approach Scanning Ion Conductance Microscopy.

Shevchuk A, Tokar S, Gopal S, Sanchez-Alonso JL, Tarasov AI, Vélez-Ortega AC, Chiappini C, Rorsman P, Stevens MM, Gorelik J, Frolenkov GI, Klenerman D, Korchev YE.

Biophys J. 2016 May 24;110(10):2252-65. doi: 10.1016/j.bpj.2016.04.017.

9.

PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery.

Ramracheya RD, McCulloch LJ, Clark A, Wiggins D, Johannessen H, Olsen MK, Cai X, Zhao CM, Chen D, Rorsman P.

Cell Rep. 2016 May 3;15(5):944-50. doi: 10.1016/j.celrep.2016.03.091. Epub 2016 Apr 21.

10.

Improving the physiological realism of experimental models.

Vinnakota KC, Cha CY, Rorsman P, Balaban RS, La Gerche A, Wade-Martins R, Beard DA, Jeneson JA.

Interface Focus. 2016 Apr 6;6(2):20150076. doi: 10.1098/rsfs.2015.0076. Review.

11.

Glucagon secretion from pancreatic α-cells.

Briant L, Salehi A, Vergari E, Zhang Q, Rorsman P.

Ups J Med Sci. 2016 May;121(2):113-9. doi: 10.3109/03009734.2016.1156789. Epub 2016 Apr 4.

12.

High-content screening identifies a role for Na(+) channels in insulin production.

Szabat M, Modi H, Ramracheya R, Girbinger V, Chan F, Lee JT, Piske M, Kamal S, Carol Yang YH, Welling A, Rorsman P, Johnson JD.

R Soc Open Sci. 2015 Dec 2;2(12):150306. doi: 10.1098/rsos.150306. eCollection 2015 Dec.

13.

Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion.

Collins SC, Do HW, Hastoy B, Hugill A, Adam J, Chibalina MV, Galvanovskis J, Godazgar M, Lee S, Goldsworthy M, Salehi A, Tarasov AI, Rosengren AH, Cox R, Rorsman P.

Diabetes. 2016 Jul;65(7):1952-61. doi: 10.2337/db15-1489. Epub 2016 Mar 18.

14.

Dramatis Personae in β-Cell Mass Regulation: Enter SerpinB1.

Tarasov AI, Rorsman P.

Cell Metab. 2016 Jan 12;23(1):8-10. doi: 10.1016/j.cmet.2015.12.011.

15.

The two pore channel TPC2 is dispensable in pancreatic β-cells for normal Ca²⁺ dynamics and insulin secretion.

Cane MC, Parrington J, Rorsman P, Galione A, Rutter GA.

Cell Calcium. 2016 Jan;59(1):32-40. doi: 10.1016/j.ceca.2015.12.004. Epub 2015 Dec 23.

16.

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.

Shigeto M, Ramracheya R, Tarasov AI, Cha CY, Chibalina MV, Hastoy B, Philippaert K, Reinbothe T, Rorsman N, Salehi A, Sones WR, Vergari E, Weston C, Gorelik J, Katsura M, Nikolaev VO, Vennekens R, Zaccolo M, Galione A, Johnson PR, Kaku K, Ladds G, Rorsman P.

J Clin Invest. 2015 Dec;125(12):4714-28. doi: 10.1172/JCI81975. Epub 2015 Nov 16.

17.

Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells.

Wu B, Wei S, Petersen N, Ali Y, Wang X, Bacaj T, Rorsman P, Hong W, Südhof TC, Han W.

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9996-10001. doi: 10.1073/pnas.1513004112. Epub 2015 Jul 27.

18.

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells.

Arredouani A, Ruas M, Collins SC, Parkesh R, Clough F, Pillinger T, Coltart G, Rietdorf K, Royle A, Johnson P, Braun M, Zhang Q, Sones W, Shimomura K, Morgan AJ, Lewis AM, Chuang KT, Tunn R, Gadea J, Teboul L, Heister PM, Tynan PW, Bellomo EA, Rutter GA, Rorsman P, Churchill GC, Parrington J, Galione A.

J Biol Chem. 2015 Aug 28;290(35):21376-92. doi: 10.1074/jbc.M115.671248. Epub 2015 Jul 7.

19.

RFX6 regulates insulin secretion by modulating Ca2+ homeostasis in human β cells.

Chandra V, Albagli-Curiel O, Hastoy B, Piccand J, Randriamampita C, Vaillant E, Cavé H, Busiah K, Froguel P, Vaxillaire M, Rorsman P, Polak M, Scharfmann R.

Cell Rep. 2014 Dec 24;9(6):2206-18. doi: 10.1016/j.celrep.2014.11.010. Epub 2014 Dec 11.

20.

Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.

Gheni G, Ogura M, Iwasaki M, Yokoi N, Minami K, Nakayama Y, Harada K, Hastoy B, Wu X, Takahashi H, Kimura K, Matsubara T, Hoshikawa R, Hatano N, Sugawara K, Shibasaki T, Inagaki N, Bamba T, Mizoguchi A, Fukusaki E, Rorsman P, Seino S.

Cell Rep. 2014 Oct 23;9(2):661-73. doi: 10.1016/j.celrep.2014.09.030. Epub 2014 Oct 16.

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