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Items: 1 to 20 of 47

1.

Rapid and fulminant leptomeningeal spread following radiotherapy in diffuse intrinsic pontine glioma.

Tinkle CL, Orr BA, Lucas JT Jr, Klimo P, Patay Z, Baker SJ, Broniscer A, Qaddoumi I.

Pediatr Blood Cancer. 2017 Jan 13. doi: 10.1002/pbc.26416. [Epub ahead of print]

PMID:
28084680
2.

Bithalamic Gliomas May Be Molecularly Distinct From Their Unilateral High-Grade Counterparts.

Broniscer A, Hwang SN, Chamdine O, Lin T, Pounds S, Onar-Thomas A, Chi L, Shurtleff S, Allen S, Gajjar A, Northcott P, Orr BA.

Brain Pathol. 2016 Dec 28. doi: 10.1111/bpa.12484. [Epub ahead of print]

PMID:
28032389
3.

NHERF1/EBP50 and NF2 as diagnostic markers for choroid plexus tumors.

Georgescu MM, Mobley BC, Orr BA, Shang P, Lehman NL, Zhu X, O'Neill TJ, Rajaram V, Hatanpaa KJ, Timmons CF, Raisanen JM.

Acta Neuropathol Commun. 2016 May 27;4(1):55. doi: 10.1186/s40478-016-0329-0.

4.

Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines.

Binder ZA, Wilson KM, Salmasi V, Orr BA, Eberhart CG, Siu IM, Lim M, Weingart JD, Quinones-Hinojosa A, Bettegowda C, Kassam AB, Olivi A, Brem H, Riggins GJ, Gallia GL.

PLoS One. 2016 Mar 30;11(3):e0150271. doi: 10.1371/journal.pone.0150271.

5.

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.

Sturm D, Orr BA, Toprak UH, Hovestadt V, Jones DT, Capper D, Sill M, Buchhalter I, Northcott PA, Leis I, Ryzhova M, Koelsche C, Pfaff E, Allen SJ, Balasubramanian G, Worst BC, Pajtler KW, Brabetz S, Johann PD, Sahm F, Reimand J, Mackay A, Carvalho DM, Remke M, Phillips JJ, Perry A, Cowdrey C, Drissi R, Fouladi M, Giangaspero F, Łastowska M, Grajkowska W, Scheurlen W, Pietsch T, Hagel C, Gojo J, Lötsch D, Berger W, Slavc I, Haberler C, Jouvet A, Holm S, Hofer S, Prinz M, Keohane C, Fried I, Mawrin C, Scheie D, Mobley BC, Schniederjan MJ, Santi M, Buccoliero AM, Dahiya S, Kramm CM, von Bueren AO, von Hoff K, Rutkowski S, Herold-Mende C, Frühwald MC, Milde T, Hasselblatt M, Wesseling P, Rößler J, Schüller U, Ebinger M, Schittenhelm J, Frank S, Grobholz R, Vajtai I, Hans V, Schneppenheim R, Zitterbart K, Collins VP, Aronica E, Varlet P, Puget S, Dufour C, Grill J, Figarella-Branger D, Wolter M, Schuhmann MU, Shalaby T, Grotzer M, van Meter T, Monoranu CM, Felsberg J, Reifenberger G, Snuderl M, Forrester LA, Koster J, Versteeg R, Volckmann R, van Sluis P, Wolf S, Mikkelsen T, Gajjar A, Aldape K, Moore AS, Taylor MD, Jones C, Jabado N, Karajannis MA, Eils R, Schlesner M, Lichter P, von Deimling A, Pfister SM, Ellison DW, Korshunov A, Kool M.

Cell. 2016 Feb 25;164(5):1060-72. doi: 10.1016/j.cell.2016.01.015.

PMID:
26919435
6.

Active medulloblastoma enhancers reveal subgroup-specific cellular origins.

Lin CY, Erkek S, Tong Y, Yin L, Federation AJ, Zapatka M, Haldipur P, Kawauchi D, Risch T, Warnatz HJ, Worst BC, Ju B, Orr BA, Zeid R, Polaski DR, Segura-Wang M, Waszak SM, Jones DT, Kool M, Hovestadt V, Buchhalter I, Sieber L, Johann P, Chavez L, Gröschel S, Ryzhova M, Korshunov A, Chen W, Chizhikov VV, Millen KJ, Amstislavskiy V, Lehrach H, Yaspo ML, Eils R, Lichter P, Korbel JO, Pfister SM, Bradner JE, Northcott PA.

Nature. 2016 Feb 4;530(7588):57-62. doi: 10.1038/nature16546.

7.

Gliomatosis cerebri in children shares molecular characteristics with other pediatric gliomas.

Broniscer A, Chamdine O, Hwang S, Lin T, Pounds S, Onar-Thomas A, Shurtleff S, Allen S, Gajjar A, Northcott P, Orr BA.

Acta Neuropathol. 2016 Feb;131(2):299-307. doi: 10.1007/s00401-015-1532-y.

PMID:
26744350
8.

Phase I study of 5-fluorouracil in children and young adults with recurrent ependymoma.

Wright KD, Daryani VM, Turner DC, Onar-Thomas A, Boulos N, Orr BA, Gilbertson RJ, Stewart CF, Gajjar A.

Neuro Oncol. 2015 Dec;17(12):1620-7. doi: 10.1093/neuonc/nov181.

9.

Malignant brainstem tumors in children, excluding diffuse intrinsic pontine gliomas.

Klimo P Jr, Nesvick CL, Broniscer A, Orr BA, Choudhri AF.

J Neurosurg Pediatr. 2016 Jan;17(1):57-65. doi: 10.3171/2015.6.PEDS15166.

PMID:
26474099
10.

A clinicopathologic study of diencephalic pediatric low-grade gliomas with BRAF V600 mutation.

Ho CY, Mobley BC, Gordish-Dressman H, VandenBussche CJ, Mason GE, Bornhorst M, Esbenshade AJ, Tehrani M, Orr BA, LaFrance DR, Devaney JM, Meltzer BW, Hofherr SE, Burger PC, Packer RJ, Rodriguez FJ.

Acta Neuropathol. 2015 Oct;130(4):575-85. doi: 10.1007/s00401-015-1467-3.

PMID:
26264609
11.

Pharmacologic Wnt Inhibition Reduces Proliferation, Survival, and Clonogenicity of Glioblastoma Cells.

Kahlert UD, Suwala AK, Koch K, Natsumeda M, Orr BA, Hayashi M, Maciaczyk J, Eberhart CG.

J Neuropathol Exp Neurol. 2015 Sep;74(9):889-900. doi: 10.1097/NEN.0000000000000227.

12.

Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.

Robinson GW, Orr BA, Wu G, Gururangan S, Lin T, Qaddoumi I, Packer RJ, Goldman S, Prados MD, Desjardins A, Chintagumpala M, Takebe N, Kaste SC, Rusch M, Allen SJ, Onar-Thomas A, Stewart CF, Fouladi M, Boyett JM, Gilbertson RJ, Curran T, Ellison DW, Gajjar A.

J Clin Oncol. 2015 Aug 20;33(24):2646-54. doi: 10.1200/JCO.2014.60.1591.

13.

Atypical teratoid/rhabdoid tumor (ATRT) arising from the 3rd cranial nerve in infants: a clinical-radiological entity?

Oh CC, Orr BA, Bernardi B, Garré ML, Rossi A, Figà-Talamanca L, Robinson GW, Patay Z.

J Neurooncol. 2015 Sep;124(2):175-83. doi: 10.1007/s11060-015-1787-0.

14.

Cervicomedullary tumors in children.

McAbee JH, Modica J, Thompson CJ, Broniscer A, Orr B, Choudhri AF, Boop FA, Klimo P Jr.

J Neurosurg Pediatr. 2015 Oct;16(4):357-66. doi: 10.3171/2015.5.PEDS14638.

PMID:
26114990
15.

Alisertib is active as single agent in recurrent atypical teratoid rhabdoid tumors in 4 children.

Wetmore C, Boyett J, Li S, Lin T, Bendel A, Gajjar A, Orr BA.

Neuro Oncol. 2015 Jun;17(6):882-8. doi: 10.1093/neuonc/nov017.

16.

Oncogenic KRAS promotes malignant brain tumors in zebrafish.

Ju B, Chen W, Orr BA, Spitsbergen JM, Jia S, Eden CJ, Henson HE, Taylor MR.

Mol Cancer. 2015 Feb 3;14:18. doi: 10.1186/s12943-015-0288-2.

17.

Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target.

Weingart MF, Roth JJ, Hutt-Cabezas M, Busse TM, Kaur H, Price A, Maynard R, Rubens J, Taylor I, Mao XG, Xu J, Kuwahara Y, Allen SJ, Erdreich-Epstein A, Weissman BE, Orr BA, Eberhart CG, Biegel JA, Raabe EH.

Oncotarget. 2015 Feb 20;6(5):3165-77.

18.

ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres.

Kahlert UD, Suwala AK, Raabe EH, Siebzehnrubl FA, Suarez MJ, Orr BA, Bar EE, Maciaczyk J, Eberhart CG.

Brain Pathol. 2015 Nov;25(6):724-32. doi: 10.1111/bpa.12240.

19.

Enophthalmos and choroidal atrophy after intraophthalmic artery chemotherapy for retinoblastoma.

Tse BC, Kaste SC, Brennan R, Orr B, Wilson MW.

Ophthalmology. 2015 Feb;122(2):435-7. doi: 10.1016/j.ophtha.2014.09.021. No abstract available.

PMID:
25439599
20.

Subsequent neoplasms in survivors of childhood central nervous system tumors: risk after modern multimodal therapy.

Tsui K, Gajjar A, Li C, Srivastava D, Broniscer A, Wetmore C, Kun LE, Merchant TE, Ellison DW, Orr BA, Boop FA, Klimo P, Ross J, Robison LL, Armstrong GT.

Neuro Oncol. 2015 Mar;17(3):448-56. doi: 10.1093/neuonc/nou279.

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