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Items: 1 to 20 of 235

1.

Self-assembling sequence-adaptive peptide nucleic acids.

Ura Y, Beierle JM, Leman LJ, Orgel LE, Ghadiri MR.

Science. 2009 Jul 3;325(5936):73-7. doi: 10.1126/science.1174577. Epub 2009 Jun 11.

2.

The implausibility of metabolic cycles on the prebiotic Earth.

Orgel LE.

PLoS Biol. 2008 Jan;6(1):e18. doi: 10.1371/journal.pbio.0060018. No abstract available.

3.

Protein disulfide oxidoreductases and the evolution of thermophily: was the last common ancestor a heat-loving microbe?

Becerra A, Delaye L, Lazcano A, Orgel LE.

J Mol Evol. 2007 Sep;65(3):296-303. Epub 2007 Aug 29.

PMID:
17726569
4.

Geothermal synthesis and metabolism.

Orgel LE.

Astrobiology. 2006 Apr;6(2):297-8. No abstract available.

PMID:
16689646
5.

Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide.

Leman LJ, Orgel LE, Ghadiri MR.

J Am Chem Soc. 2006 Jan 11;128(1):20-1.

PMID:
16390101
6.

Molecular biology. Retrospective: Francis Crick (1916-2004).

Orgel LE.

Science. 2004 Aug 20;305(5687):1118. No abstract available.

PMID:
15326346
7.

Prebiotic adenine revisited: eutectics and photochemistry.

Orgel LE.

Orig Life Evol Biosph. 2004 Aug;34(4):361-9.

PMID:
15279171
8.

Prebiotic chemistry and the origin of the RNA world.

Orgel LE.

Crit Rev Biochem Mol Biol. 2004 Mar-Apr;39(2):99-123. Review.

PMID:
15217990
9.

Some consequences of the RNA world hypothesis.

Orgel LE.

Orig Life Evol Biosph. 2003 Apr;33(2):211-8.

PMID:
12967268
10.

Is cyanoacetylene prebiotic?

Orgel LE.

Orig Life Evol Biosph. 2002 Jun;32(3):279-81.

PMID:
12227432
11.

Synthesis of adenine from HCN tetramer and ammonium formate.

Hill A, Orgel LE.

Orig Life Evol Biosph. 2002 Apr;32(2):99-102.

PMID:
12185678
12.

Sequence dependent N-terminal rearrangement and degradation of peptide nucleic acid (PNA) in aqueous solution.

Eriksson M, Christensen L, Schmidt J, Haaima G, Orgel L, Nielsen PE.

Nouv J Chim. 1998;22:1055-9.

PMID:
11543609
13.

Nonenzymatic synthesis of RNA and DNA oligomers on hexitol nucleic acid templates: the importance of the A structure.

Kozlov IA, Politis PK, Van Aerschot A, Busson R, Herdewijn P, Orgel LE.

J Am Chem Soc. 1999 Mar 31;121(12):2653-6.

PMID:
11543583
14.
15.

A comparison of RNA with DNA in template-directed synthesis.

Zielinski M, Kozlov IA, Orgel LE.

Helv Chim Acta. 2000 Sep-Oct;83(8):1678-84.

PMID:
11543568
16.

Efficient transfer of information from hexitol nucleic acids to RNA during nonenzymatic oligomerization.

Kozlov IA, De Bouvere B, Van Aerschot A, Herdewijn P, Orgel LE.

J Am Chem Soc. 1999;121(25):5856-9.

PMID:
11542282
17.

Formation of oligonucleotide-PNA-chimeras by template-directed ligation.

Koppitz M, Nielsen PE, Orgel LE.

J Am Chem Soc. 1998;120(19):4563-9.

PMID:
11541746
18.

A highly enantio-selective hexitol nucleic acid template for nonenzymatic oligoguanylate synthesis.

Kozlov IA, Politis PK, Pitsch S, Herdewijn P, Orgel LE.

J Am Chem Soc. 1999;121(5):1108-9. No abstract available.

PMID:
11541447
19.

The origins of life--a status report.

Joyce GF, Orgel LE.

Am Biol Teach. 1998 Jan;60(1):10-2. No abstract available.

PMID:
11541103
20.

The origin of life--how long did it take?

Orgel LE.

Orig Life Evol Biosph. 1998 Feb;28(1):91-6.

PMID:
11536858

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