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Items: 1 to 20 of 42


Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context.

Joslin EJ, Shankaran H, Opresko LK, Bollinger N, Lauffenburger DA, Wiley HS.

Mol Biosyst. 2010 Jul;6(7):1293-306. doi: 10.1039/c003921g.


Three-dimensional culture conditions lead to decreased radiation induced cytotoxicity in human mammary epithelial cells.

Sowa MB, Chrisler WB, Zens KD, Ashjian EJ, Opresko LK.

Mutat Res. 2010 May 1;687(1-2):78-83. doi: 10.1016/j.mrfmmm.2010.03.004.


Basic fibroblast growth factor regulates persistent ERK oscillations in premalignant but not malignant JB6 cells.

Weber TJ, Shankaran H, Wiley HS, Opresko LK, Chrisler WB, Quesenberry RD.

J Invest Dermatol. 2010 May;130(5):1444-56. doi: 10.1038/jid.2009.383.


Rapid and sustained nuclear-cytoplasmic ERK oscillations induced by epidermal growth factor.

Shankaran H, Ippolito DL, Chrisler WB, Resat H, Bollinger N, Opresko LK, Wiley HS.

Mol Syst Biol. 2009;5:332. doi: 10.1038/msb.2009.90.


HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells.

Zhang Y, Opresko L, Shankaran H, Chrisler WB, Wiley HS, Resat H.

BMC Cell Biol. 2009 Oct 31;10:78. doi: 10.1186/1471-2121-10-78.


Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.

Weber TJ, Opresko LK, Waisman DM, Newton GJ, Quesenberry RD, Bollinger N, Moore RJ, Smith RD.

Radiat Res. 2009 Jul;172(1):96-105. doi: 10.1667/RR1220.1.


An extensive survey of tyrosine phosphorylation revealing new sites in human mammary epithelial cells.

Heibeck TH, Ding SJ, Opresko LK, Zhao R, Schepmoes AA, Yang F, Tolmachev AV, Monroe ME, Camp DG 2nd, Smith RD, Wiley HS, Qian WJ.

J Proteome Res. 2009 Aug;8(8):3852-61. doi: 10.1021/pr900044c.


Cellular dichotomy between anchorage-independent growth responses to bFGF and TPA reflects molecular switch in commitment to carcinogenesis.

Waters KM, Tan R, Opresko LK, Quesenberry RD, Bandyopadhyay S, Chrisler WB, Weber TJ.

Mol Carcinog. 2009 Nov;48(11):1059-69. doi: 10.1002/mc.20558.


System theoretical investigation of human epidermal growth factor receptor-mediated signalling.

Zhang Y, Shankaran H, Opresko L, Resat H.

IET Syst Biol. 2008 Sep;2(5):273-84. doi: 10.1049/iet-syb:20080116.


Multiple mechanisms are responsible for transactivation of the epidermal growth factor receptor in mammary epithelial cells.

Rodland KD, Bollinger N, Ippolito D, Opresko LK, Coffey RJ, Zangar R, Wiley HS.

J Biol Chem. 2008 Nov 14;283(46):31477-87. doi: 10.1074/jbc.M800456200.


Quantifying the effects of co-expressing EGFR and HER2 on HER activation and trafficking.

Shankaran H, Zhang Y, Opresko L, Resat H.

Biochem Biophys Res Commun. 2008 Jun 27;371(2):220-4. doi: 10.1016/j.bbrc.2008.04.043.


EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation.

Joslin EJ, Opresko LK, Wells A, Wiley HS, Lauffenburger DA.

J Cell Sci. 2007 Oct 15;120(Pt 20):3688-99.


Cellular trafficking of phospholamban and formation of functional sarcoplasmic reticulum during myocyte differentiation.

Stenoien DL, Knyushko TV, Londono MP, Opresko LK, Mayer MU, Brady ST, Squier TC, Bigelow DJ.

Am J Physiol Cell Physiol. 2007 Jun;292(6):C2084-94.


High speed method for in situ multispectral image registration.

Perrine KA, Lamarche BL, Hopkins DF, Budge SE, Opresko LK, Wiley HS, Sowa MB.

Microsc Res Tech. 2007 Apr;70(4):382-9.


Cholesterol dictates the freedom of EGF receptors and HER2 in the plane of the membrane.

Orr G, Hu D, Oz├želik S, Opresko LK, Wiley HS, Colson SD.

Biophys J. 2005 Aug;89(2):1362-73.


The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode.

Dong J, Opresko LK, Chrisler W, Orr G, Quesenberry RD, Lauffenburger DA, Wiley HS.

Mol Biol Cell. 2005 Jun;16(6):2984-98.


A model of cytokine shedding induced by low doses of gamma radiation.

Miller JH, Zheng F, Jin S, Opresko LK, Wiley HS, Resat H.

Radiat Res. 2005 Mar;163(3):337-42.


Induced autocrine signaling through the epidermal growth factor receptor contributes to the response of mammary epithelial cells to tumor necrosis factor alpha.

Chen WN, Woodbury RL, Kathmann LE, Opresko LK, Zangar RC, Wiley HS, Thrall BD.

J Biol Chem. 2004 Apr 30;279(18):18488-96.

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