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Items: 1 to 20 of 509

1.

Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity.

Ying W, Riopel M, Bandyopadhyay G, Dong Y, Birmingham A, Seo JB, Ofrecio JM, Wollam J, Hernandez-Carretero A, Fu W, Li P, Olefsky JM.

Cell. 2017 Oct 5;171(2):372-384.e12. doi: 10.1016/j.cell.2017.08.035. Epub 2017 Sep 21.

PMID:
28942920
2.

Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling.

Ying W, Wollam J, Ofrecio JM, Bandyopadhyay G, El Ouarrat D, Lee YS, Oh DY, Li P, Osborn O, Olefsky JM.

J Clin Invest. 2017 Mar 1;127(3):1019-1030. doi: 10.1172/JCI90350. Epub 2017 Feb 13.

3.

Inflammatory mechanisms linking obesity and metabolic disease.

Saltiel AR, Olefsky JM.

J Clin Invest. 2017 Jan 3;127(1):1-4. doi: 10.1172/JCI92035. Epub 2017 Jan 3. Review.

4.

Obese Neuronal PPARγ Knockout Mice Are Leptin Sensitive but Show Impaired Glucose Tolerance and Fertility.

Fernandez MO, Sharma S, Kim S, Rickert E, Hsueh K, Hwang V, Olefsky JM, Webster NJ.

Endocrinology. 2017 Jan 1;158(1):121-133. doi: 10.1210/en.2016-1818.

PMID:
27841948
5.

Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance.

Li P, Liu S, Lu M, Bandyopadhyay G, Oh D, Imamura T, Johnson AMF, Sears D, Shen Z, Cui B, Kong L, Hou S, Liang X, Iovino S, Watkins SM, Ying W, Osborn O, Wollam J, Brenner M, Olefsky JM.

Cell. 2016 Nov 3;167(4):973-984.e12. doi: 10.1016/j.cell.2016.10.025.

6.

G protein-coupled receptors as targets for anti-diabetic therapeutics.

Oh DY, Olefsky JM.

Nat Rev Drug Discov. 2016 Mar;15(3):161-72. doi: 10.1038/nrd.2015.4. Epub 2016 Jan 29. Review.

PMID:
26822831
7.

p75 Neurotrophin Receptor Regulates Energy Balance in Obesity.

Baeza-Raja B, Sachs BD, Li P, Christian F, Vagena E, Davalos D, Le Moan N, Ryu JK, Sikorski SL, Chan JP, Scadeng M, Taylor SS, Houslay MD, Baillie GS, Saltiel AR, Olefsky JM, Akassoglou K.

Cell Rep. 2016 Jan 12;14(2):255-68. doi: 10.1016/j.celrep.2015.12.028. Epub 2015 Dec 31.

8.

Regulation of metabolism by the innate immune system.

Lackey DE, Olefsky JM.

Nat Rev Endocrinol. 2016 Jan;12(1):15-28. doi: 10.1038/nrendo.2015.189. Epub 2015 Nov 10. Review.

PMID:
26553134
9.

Spatial Cognition in Adult and Aged Mice Exposed to High-Fat Diet.

Kesby JP, Kim JJ, Scadeng M, Woods G, Kado DM, Olefsky JM, Jeste DV, Achim CL, Semenova S.

PLoS One. 2015 Oct 8;10(10):e0140034. doi: 10.1371/journal.pone.0140034. eCollection 2015.

10.

GPR43 Potentiates β-Cell Function in Obesity.

McNelis JC, Lee YS, Mayoral R, van der Kant R, Johnson AM, Wollam J, Olefsky JM.

Diabetes. 2015 Sep;64(9):3203-17. doi: 10.2337/db14-1938. Epub 2015 May 28.

11.

Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity.

Mayoral R, Osborn O, McNelis J, Johnson AM, Oh DY, Izquierdo CL, Chung H, Li P, Traves PG, Bandyopadhyay G, Pessentheiner AR, Ofrecio JM, Cook JR, Qiang L, Accili D, Olefsky JM.

Mol Metab. 2015 Mar 5;4(5):378-91. doi: 10.1016/j.molmet.2015.02.007. eCollection 2015 May.

12.

High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability.

Johnson AM, Costanzo A, Gareau MG, Armando AM, Quehenberger O, Jameson JM, Olefsky JM.

PLoS One. 2015 Apr 2;10(4):e0122195. doi: 10.1371/journal.pone.0122195. eCollection 2015.

13.

Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.

Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM.

Nature. 2015 Apr 16;520(7547):388. doi: 10.1038/nature14304. Epub 2015 Mar 4. No abstract available.

PMID:
25739500
14.

LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes.

Li P, Oh DY, Bandyopadhyay G, Lagakos WS, Talukdar S, Osborn O, Johnson A, Chung H, Maris M, Ofrecio JM, Taguchi S, Lu M, Olefsky JM.

Nat Med. 2015 Mar;21(3):239-247. doi: 10.1038/nm.3800. Epub 2015 Feb 23.

15.

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance.

Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky JM, Saltiel AR, Downes M, Evans RM.

Nat Med. 2015 Feb;21(2):159-65. doi: 10.1038/nm.3760. Epub 2015 Jan 5.

16.

Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice.

Morinaga H, Mayoral R, Heinrichsdorff J, Osborn O, Franck N, Hah N, Walenta E, Bandyopadhyay G, Pessentheiner AR, Chi TJ, Chung H, Bogner-Strauss JG, Evans RM, Olefsky JM, Oh DY.

Diabetes. 2015 Apr;64(4):1120-30. doi: 10.2337/db14-1238. Epub 2014 Oct 14.

17.

Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer.

Chung H, Lee YS, Mayoral R, Oh DY, Siu JT, Webster NJ, Sears DD, Olefsky JM, Ellies LG.

Oncogene. 2015 Jul;34(27):3504-13. doi: 10.1038/onc.2014.283. Epub 2014 Sep 15.

18.

Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer.

Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM.

Nature. 2014 Sep 18;513(7518):436-9. doi: 10.1038/nature13540. Epub 2014 Jul 16. Erratum in: Nature. 2015 Apr 16;520(7547):388.

19.

Macrophages, immunity, and metabolic disease.

McNelis JC, Olefsky JM.

Immunity. 2014 Jul 17;41(1):36-48. doi: 10.1016/j.immuni.2014.05.010. Review.

20.

A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.

Oh DY, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, Chung H, Evans RM, Quehenberger O, McNelis J, Bogner-Strauss JG, Olefsky JM.

Nat Med. 2014 Aug;20(8):942-7. doi: 10.1038/nm.3614. Epub 2014 Jul 6.

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