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Items: 1 to 20 of 75

1.

ELKS/Voltage-Dependent Ca2+ Channel-β Subunit Module Regulates Polarized Ca2+ Influx in Pancreatic β Cells.

Ohara-Imaizumi M, Aoyagi K, Yamauchi H, Yoshida M, Mori MX, Hida Y, Tran HN, Ohkura M, Abe M, Akimoto Y, Nakamichi Y, Nishiwaki C, Kawakami H, Hara K, Sakimura K, Nagamatsu S, Mori Y, Nakai J, Kakei M, Ohtsuka T.

Cell Rep. 2019 Jan 29;26(5):1213-1226.e7. doi: 10.1016/j.celrep.2018.12.106.

2.

VAMP7 Regulates Autophagosome Formation by Supporting Atg9a Functions in Pancreatic β-Cells From Male Mice.

Aoyagi K, Itakura M, Fukutomi T, Nishiwaki C, Nakamichi Y, Torii S, Makiyama T, Harada A, Ohara-Imaizumi M.

Endocrinology. 2018 Nov 1;159(11):3674-3688. doi: 10.1210/en.2018-00447.

PMID:
30215699
3.

In vivo regulation of glycogen synthase kinase 3β activity in neurons and brains.

Krishnankutty A, Kimura T, Saito T, Aoyagi K, Asada A, Takahashi SI, Ando K, Ohara-Imaizumi M, Ishiguro K, Hisanaga SI.

Sci Rep. 2017 Aug 17;7(1):8602. doi: 10.1038/s41598-017-09239-5.

4.

Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells.

Kunii M, Ohara-Imaizumi M, Takahashi N, Kobayashi M, Kawakami R, Kondoh Y, Shimizu T, Simizu S, Lin B, Nunomura K, Aoyagi K, Ohno M, Ohmuraya M, Sato T, Yoshimura SI, Sato K, Harada R, Kim YJ, Osada H, Nemoto T, Kasai H, Kitamura T, Nagamatsu S, Harada A.

J Cell Biol. 2016 Oct 10;215(1):121-138. Epub 2016 Oct 3.

5.

VAMP7 Regulates Autophagy to Maintain Mitochondrial Homeostasis and to Control Insulin Secretion in Pancreatic β-Cells.

Aoyagi K, Ohara-Imaizumi M, Itakura M, Torii S, Akimoto Y, Nishiwaki C, Nakamichi Y, Kishimoto T, Kawakami H, Harada A, Takahashi M, Nagamatsu S.

Diabetes. 2016 Jun;65(6):1648-59. doi: 10.2337/db15-1207. Epub 2016 Mar 7.

6.

Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state.

Kim K, Oh CM, Ohara-Imaizumi M, Park S, Namkung J, Yadav VK, Tamarina NA, Roe MW, Philipson LH, Karsenty G, Nagamatsu S, German MS, Kim H.

Endocrinology. 2015 Feb;156(2):444-52. doi: 10.1210/en.2014-1687. Epub 2014 Nov 26.

7.

Serotonin regulates glucose-stimulated insulin secretion from pancreatic β cells during pregnancy.

Ohara-Imaizumi M, Kim H, Yoshida M, Fujiwara T, Aoyagi K, Toyofuku Y, Nakamichi Y, Nishiwaki C, Okamura T, Uchida T, Fujitani Y, Akagawa K, Kakei M, Watada H, German MS, Nagamatsu S.

Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19420-5. doi: 10.1073/pnas.1310953110. Epub 2013 Nov 11.

8.

Acute inhibition of PI3K-PDK1-Akt pathway potentiates insulin secretion through upregulation of newcomer granule fusions in pancreatic β-cells.

Aoyagi K, Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Ueki K, Kadowaki T, Nagamatsu S.

PLoS One. 2012;7(10):e47381. doi: 10.1371/journal.pone.0047381. Epub 2012 Oct 15.

9.

DPP-4 inhibitor des-F-sitagliptin treatment increased insulin exocytosis from db/db mice β cells.

Nagamatsu S, Ohara-Imaizumi M, Nakamichi Y, Aoyagi K, Nishiwaki C.

Biochem Biophys Res Commun. 2011 Sep 9;412(4):556-60. doi: 10.1016/j.bbrc.2011.07.119. Epub 2011 Aug 10.

PMID:
21854759
10.

Dissociation of inositol polyphosphates from the C2B domain of synaptotagmin facilitates spontaneous release of catecholamines in adrenal chromaffin cells. A suggestive evidence of a fusion clamp by synaptotagmin.

Sasakawa N, Ohara-Imaizumi M, Fukuda M, Kabayama H, Mikoshiba K, Kumakura K.

Neuropharmacology. 2011 Jun;60(7-8):1364-70. doi: 10.1016/j.neuropharm.2011.03.005. Epub 2011 Mar 12.

PMID:
21402086
11.

Regulation of resident and newcomer insulin granules by calcium and SNARE proteins.

Aoyagi K, Ohara-Imaizumi M, Nagamatsu S.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1197-210. Review.

PMID:
21196227
12.

Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis.

Ohara-Imaizumi M, Yoshida M, Aoyagi K, Saito T, Okamura T, Takenaka H, Akimoto Y, Nakamichi Y, Takanashi-Yanobu R, Nishiwaki C, Kawakami H, Kato N, Hisanaga S, Kakei M, Nagamatsu S.

PLoS One. 2010 Dec 9;5(12):e15553. doi: 10.1371/journal.pone.0015553.

13.

Insulin/phosphoinositide 3-kinase pathway accelerates the glucose-induced first-phase insulin secretion through TrpV2 recruitment in pancreatic β-cells.

Aoyagi K, Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Nagamatsu S.

Biochem J. 2010 Dec 1;432(2):375-86. doi: 10.1042/BJ20100864.

PMID:
20854263
14.

Gαo represses insulin secretion by reducing vesicular docking in pancreatic beta-cells.

Zhao A, Ohara-Imaizumi M, Brissova M, Benninger RK, Xu Y, Hao Y, Abramowitz J, Boulay G, Powers AC, Piston D, Jiang M, Nagamatsu S, Birnbaumer L, Gu G.

Diabetes. 2010 Oct;59(10):2522-9. doi: 10.2337/db09-1719. Epub 2010 Jul 9.

15.

Glinide, but not sulfonylurea, can evoke insulin exocytosis by repetitive stimulation: imaging analysis of insulin exocytosis by secretagogue-induced repetitive stimulations.

Aoyagi K, Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Nagamatsu S.

Exp Diabetes Res. 2009;2009:278762. doi: 10.1155/2009/278762. Epub 2009 Dec 28.

16.

Imaging exocytosis of single glucagon-like peptide-1 containing granules in a murine enteroendocrine cell line with total internal reflection fluorescent microscopy.

Ohara-Imaizumi M, Aoyagi K, Akimoto Y, Nakamichi Y, Nishiwaki C, Kawakami H, Nagamatsu S.

Biochem Biophys Res Commun. 2009 Dec 4;390(1):16-20. doi: 10.1016/j.bbrc.2009.09.043. Epub 2009 Sep 18.

PMID:
19766598
17.

Pattern of rise in subplasma membrane Ca2+ concentration determines type of fusing insulin granules in pancreatic beta cells.

Ohara-Imaizumi M, Aoyagi K, Nakamichi Y, Nishiwaki C, Sakurai T, Nagamatsu S.

Biochem Biophys Res Commun. 2009 Jul 31;385(3):291-5. doi: 10.1016/j.bbrc.2009.04.155. Epub 2009 May 6.

PMID:
19426714
18.

Change in long-spacing collagen in Descemet's membrane of diabetic Goto-Kakizaki rats and its suppression by antidiabetic agents.

Akimoto Y, Sawada H, Ohara-Imaizumi M, Nagamatsu S, Kawakami H.

Exp Diabetes Res. 2008;2008:818341. doi: 10.1155/2008/818341.

19.

Imaging exocytosis of single insulin secretory granules with TIRF microscopy.

Nagamatsu S, Ohara-Imaizumi M.

Methods Mol Biol. 2008;440:259-68. doi: 10.1007/978-1-59745-178-9_20.

PMID:
18369952
20.

Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration.

Okamoto M, Ohara-Imaizumi M, Kubota N, Hashimoto S, Eto K, Kanno T, Kubota T, Wakui M, Nagai R, Noda M, Nagamatsu S, Kadowaki T.

Diabetologia. 2008 May;51(5):827-35. doi: 10.1007/s00125-008-0944-9. Epub 2008 Mar 28.

PMID:
18369586

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