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Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs.

Guzzo MB, Nguyen HT, Pham TH, Wyszczelska-Rokiel M, Jakubowski H, Wolff KA, Ogwang S, Timpona JL, Gogula S, Jacobs MR, Ruetz M, Kräutler B, Jacobsen DW, Zhang GF, Nguyen L.

PLoS Pathog. 2016 Oct 19;12(10):e1005949. doi: 10.1371/journal.ppat.1005949.


Draft Genome Sequences of Mycobacterium bovis BZ 31150 and Mycobacterium bovis B2 7505, Pathogenic Bacteria Isolated from Archived Captive Animal Bronchial Washes and Human Sputum Samples in Uganda.

Wanzala SI, Nakavuma J, Travis DA, Kia P, Ogwang S, Sreevatsan S.

Genome Announc. 2015 Oct 8;3(5). pii: e01102-15. doi: 10.1128/genomeA.01102-15.


Incubation time of Mycobacterium tuberculosis complex sputum cultures in BACTEC MGIT 960: 4weeks of negative culture is enough for physicians to consider alternative diagnoses.

Ogwang S, Mubiri P, Bark CM, Joloba ML, Boom WH, Johnson JL.

Diagn Microbiol Infect Dis. 2015 Oct;83(2):162-4. doi: 10.1016/j.diagmicrobio.2015.07.002.


Sulfamethoxazole susceptibility of Mycobacterium tuberculosis isolates from HIV-infected Ugandan adults with tuberculosis taking trimethoprim-sulfamethoxazole prophylaxis.

Ogwang S, Good CE, Okware B, Nsereko M, Jacobs MR, Boom WH, Bark CM.

Antimicrob Agents Chemother. 2015 Sep;59(9):5844-6. doi: 10.1128/AAC.01101-15.


The economic burden of maternal mortality on households: evidence from three sub-counties in rural western Kenya.

Kes A, Ogwang S, Pande R, Douglas Z, Karuga R, Odhiambo FO, Laserson K, Schaffer K.

Reprod Health. 2015 May 6;12 Suppl 1:S3. doi: 10.1186/1742-4755-12-S1-S3.


Continuing with "…a heavy heart" - consequences of maternal death in rural Kenya.

Pande R, Ogwang S, Karuga R, Rajan R, Kes A, Odhiambo FO, Laserson K, Schaffer K.

Reprod Health. 2015 May 6;12 Suppl 1:S2. doi: 10.1186/1742-4755-12-S1-S2.


Use of real time polymerase chain reaction for detection of M. tuberculosis, M. avium and M. kansasii from clinical specimens.

Bainomugisa A, Wampande E, Muchwa C, Akol J, Mubiri P, Ssenyungule H, Matovu E, Ogwang S, Joloba M.

BMC Infect Dis. 2015 Apr 14;15:181. doi: 10.1186/s12879-015-0921-0.


Comparison of MGIT and Myco/F lytic liquid-based blood culture systems for recovery of Mycobacterium tuberculosis from pleural fluid.

Harausz E, Lusiba JK, Nsereko M, Johnson JL, Toossi Z, Ogwang S, Boom WH, Joloba ML; Tuberculosis Research Unit (TBRU)..

J Clin Microbiol. 2015 Apr;53(4):1391-4. doi: 10.1128/JCM.02742-14.


Pregnancy-related mortality in Africa and Asia: evidence from INDEPTH Health and Demographic Surveillance System sites.

Streatfield PK, Alam N, Compaoré Y, Rossier C, Soura AB, Bonfoh B, Jaeger F, Ngoran EK, Utzinger J, Gomez P, Jasseh M, Ansah A, Debpuur C, Oduro A, Williams J, Addei S, Gyapong M, Kukula VA, Bauni E, Mochamah G, Ndila C, Williams TN, Desai M, Moige H, Odhiambo FO, Ogwang S, Beguy D, Ezeh A, Oti S, Chihana M, Crampin A, Price A, Delaunay V, Diallo A, Douillot L, Sokhna C, Collinson MA, Kahn K, Tollman SM, Herbst K, Mossong J, Emina JB, Sankoh OA, Byass P.

Glob Health Action. 2014 Oct 29;7:25368. doi: 10.3402/gha.v7.25368.


Elucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencing.

Clark TG, Mallard K, Coll F, Preston M, Assefa S, Harris D, Ogwang S, Mumbowa F, Kirenga B, O'Sullivan DM, Okwera A, Eisenach KD, Joloba M, Bentley SD, Ellner JJ, Parkhill J, Jones-López EC, McNerney R.

PLoS One. 2013 Dec 11;8(12):e83012. doi: 10.1371/journal.pone.0083012.


Trauma-related mortality among adults in Rural Western Kenya: characterising deaths using data from a health and demographic surveillance system.

Odhiambo FO, Beynon CM, Ogwang S, Hamel MJ, Howland O, van Eijk AM, Norton R, Amek N, Slutsker L, Laserson KF, De Cock KM, Phillips-Howard PA.

PLoS One. 2013 Nov 7;8(11):e79840. doi: 10.1371/journal.pone.0079840.


Comparison of time to positive and colony counting in an early bactericidal activity study of anti-tuberculosis treatment.

Bark CM, Gitta P, Ogwang S, Nsereko M, Thiel BA, Boom WH, Eisenach KD, Joloba ML, Johnson JL.

Int J Tuberc Lung Dis. 2013 Nov;17(11):1448-51. doi: 10.5588/ijtld.13.0063.


An analysis of pregnancy-related mortality in the KEMRI/CDC health and demographic surveillance system in western Kenya.

Desai M, Phillips-Howard PA, Odhiambo FO, Katana A, Ouma P, Hamel MJ, Omoto J, Macharia S, van Eijk A, Ogwang S, Slutsker L, Laserson KF.

PLoS One. 2013 Jul 16;8(7):e68733. doi: 10.1371/journal.pone.0068733.


Profile: the KEMRI/CDC Health and Demographic Surveillance System--Western Kenya.

Odhiambo FO, Laserson KF, Sewe M, Hamel MJ, Feikin DR, Adazu K, Ogwang S, Obor D, Amek N, Bayoh N, Ombok M, Lindblade K, Desai M, ter Kuile F, Phillips-Howard P, van Eijk AM, Rosen D, Hightower A, Ofware P, Muttai H, Nahlen B, DeCock K, Slutsker L, Breiman RF, Vulule JM.

Int J Epidemiol. 2012 Aug;41(4):977-87. doi: 10.1093/ije/dys108.


Impact of directly observed sputum collection on sputum culture contamination rates.

Muzanyi G, Angel M, Nakamate T, Ogwang S, Nyole S.

Afr Health Sci. 2011 Dec;11(4):605-6. No abstract available.


Community involvement in obstetric emergency management in rural areas: a case of Rukungiri district, Western Uganda.

Ogwang S, Najjemba R, Tumwesigye NM, Orach CG.

BMC Pregnancy Childbirth. 2012 Mar 29;12:20. doi: 10.1186/1471-2393-12-20.


Bacterial conversion of folinic acid is required for antifolate resistance.

Ogwang S, Nguyen HT, Sherman M, Bajaksouzian S, Jacobs MR, Boom WH, Zhang GF, Nguyen L.

J Biol Chem. 2011 Apr 29;286(17):15377-90. doi: 10.1074/jbc.M111.231076.


Mortality and health among internally displaced persons in western Kenya following post-election violence, 2008: novel use of demographic surveillance.

Feikin DR, Adazu K, Obor D, Ogwang S, Vulule J, Hamel MJ, Laserson K.

Bull World Health Organ. 2010 Aug 1;88(8):601-8. doi: 10.2471/BLT.09.069732.


Assessment of partogram use during labour in Rujumbura Health Sub District, Rukungiri District, Uganda.

Ogwang S, Karyabakabo Z, Rutebemberwa E.

Afr Health Sci. 2009 Aug 1;9 Suppl 1:S27-34.


A lipoprotein modulates activity of the MtrAB two-component system to provide intrinsic multidrug resistance, cytokinetic control and cell wall homeostasis in Mycobacterium.

Nguyen HT, Wolff KA, Cartabuke RH, Ogwang S, Nguyen L.

Mol Microbiol. 2010 Apr;76(2):348-64. doi: 10.1111/j.1365-2958.2010.07110.x.

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