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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 3
1997 6
1998 6
1999 11
2000 32
2001 104
2002 191
2003 282
2004 435
2005 495
2006 614
2007 694
2008 754
2009 748
2010 763
2011 770
2012 829
2013 875
2014 778
2015 806
2016 732
2017 765
2018 725
2019 709
2020 655
2021 682
2022 619
2023 510
2024 156

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12,751 results

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Page 1
Function of obestatin in the digestive system.
Xing YX, Yang L, Kuang HY, Gao XY, Liu HL. Xing YX, et al. Nutrition. 2017 Feb;34:21-28. doi: 10.1016/j.nut.2016.08.009. Epub 2016 Sep 7. Nutrition. 2017. PMID: 28063509 Review.
Any abnormalities in the link may cause malnutrition, endocrine disorders, and the decline of organ functions. Obestatin, a biologically active peptide, is encoded by the ghrelin gene. ...However, the functions of obestatin are not clear, and even appear to b …
Any abnormalities in the link may cause malnutrition, endocrine disorders, and the decline of organ functions. Obestatin, a biologica …
Obestatin and cardiovascular health.
Su XJ, Dong RX, Li YP, Yang SG, Li ZF. Su XJ, et al. Peptides. 2014 Feb;52:58-60. doi: 10.1016/j.peptides.2013.11.023. Epub 2013 Dec 12. Peptides. 2014. PMID: 24333655 Review.
Obestatin, encoded by the same gene as ghrelin, was first described as a physiological opponent of ghrelin through an interaction with the orphan receptor GPR39. However, the effects of obestatin were not totally contrary to the effects of ghrelin …
Obestatin, encoded by the same gene as ghrelin, was first described as a physiological opponent of ghrelin through an i …
Diverse and Complementary Effects of Ghrelin and Obestatin.
Villarreal D, Pradhan G, Zhou Y, Xue B, Sun Y. Villarreal D, et al. Biomolecules. 2022 Mar 29;12(4):517. doi: 10.3390/biom12040517. Biomolecules. 2022. PMID: 35454106 Free PMC article. Review.
While there are ample literature documenting ghrelin's functions, the roles of obestatin are less clear and controversial. Ghrelin and obestatin have been perceived to be antagonistic initially; however, recent studies challenge this dogma. ...
While there are ample literature documenting ghrelin's functions, the roles of obestatin are less clear and controversial. …
Obestatin: is it really doing something?
Trovato L, Gallo D, Settanni F, Gesmundo I, Ghigo E, Granata R. Trovato L, et al. Front Horm Res. 2014;42:175-85. doi: 10.1159/000358346. Epub 2014 Apr 7. Front Horm Res. 2014. PMID: 24732935 Review.
Obestatin was identified in 2005 by Zhang and colleagues as a ghrelin-associated peptide, derived from posttranslational processing of the prepro-ghrelin gene. ...Finally, like ghrelin, obestatin is produced in the gastrointestinal tract, includ …
Obestatin was identified in 2005 by Zhang and colleagues as a ghrelin-associated peptide, derived from posttranslational proce …
Obestatin receptor in energy homeostasis and obesity pathogenesis.
Zhang JV, Li L, Huang Q, Ren PG. Zhang JV, et al. Prog Mol Biol Transl Sci. 2013;114:89-107. doi: 10.1016/B978-0-12-386933-3.00003-0. Prog Mol Biol Transl Sci. 2013. PMID: 23317783 Review.
Based on the bioinformatic prediction, Zhang and colleagues discovered obestatin, a new 23-amino acid hormone from rat stomach extract encoded by the ghrelin gene. Obestatin is present not only in the gastrointestinal tract, but also in the spleen, mammary gl …
Based on the bioinformatic prediction, Zhang and colleagues discovered obestatin, a new 23-amino acid hormone from rat stomach extrac …
Obestatin: a new metabolic player in the pancreas and white adipose tissue.
Gesmundo I, Gallo D, Favaro E, Ghigo E, Granata R. Gesmundo I, et al. IUBMB Life. 2013 Dec;65(12):976-82. doi: 10.1002/iub.1226. Epub 2013 Nov 12. IUBMB Life. 2013. PMID: 24217898 Free article. Review.
Obestatin is a 23 amino acid amidated peptide, member of the preproghrelin gene-derived peptides. Initially, obestatin was reported to exert opposite effects to those of ghrelin on food intake and body weight gain, through interaction with GPR39; however, the …
Obestatin is a 23 amino acid amidated peptide, member of the preproghrelin gene-derived peptides. Initially, obestatin was rep …
The Homeostatic Force of Ghrelin.
Yanagi S, Sato T, Kangawa K, Nakazato M. Yanagi S, et al. Cell Metab. 2018 Apr 3;27(4):786-804. doi: 10.1016/j.cmet.2018.02.008. Epub 2018 Mar 22. Cell Metab. 2018. PMID: 29576534 Free article. Review.
Ghrelin operates brain circuits to regulate homeostatic and hedonic feeding. ...Future studies of ghrelin will further elucidate how the stomach regulates systemic homeostasis....
Ghrelin operates brain circuits to regulate homeostatic and hedonic feeding. ...Future studies of ghrelin will further elucida …
Obestatin as a key regulator of metabolism and cardiovascular function with emerging therapeutic potential for diabetes.
Cowan E, Burch KJ, Green BD, Grieve DJ. Cowan E, et al. Br J Pharmacol. 2016 Jul;173(14):2165-81. doi: 10.1111/bph.13502. Epub 2016 May 27. Br J Pharmacol. 2016. PMID: 27111465 Free PMC article. Review.
Obestatin is a 23-amino acid C-terminally amidated gastrointestinal peptide derived from preproghrelin and which forms an alpha helix. Although obestatin has a short biological half-life and is rapidly degraded, it is proposed to exert wide-ranging pathophysiologica …
Obestatin is a 23-amino acid C-terminally amidated gastrointestinal peptide derived from preproghrelin and which forms an alpha helix …
Obestatin, obesity and diabetes.
Ren AJ, Guo ZF, Wang YK, Lin L, Zheng X, Yuan WJ. Ren AJ, et al. Peptides. 2009 Feb;30(2):439-44. doi: 10.1016/j.peptides.2008.10.002. Epub 2008 Oct 17. Peptides. 2009. PMID: 18992781 Review.
The high prevalence of obesity and diabetes will lead to higher rates of morbidity and mortality. It is well known that ghrelin plays a potential role in obesity and diabetes. Obestatin, a novel 23 amino acid amidated peptide encoded by the same gene that encodes …
The high prevalence of obesity and diabetes will lead to higher rates of morbidity and mortality. It is well known that ghrelin plays …
Biochemical properties and biological actions of obestatin and its relevence in type 2 diabetes.
Green BD, Grieve DJ. Green BD, et al. Peptides. 2018 Feb;100:249-259. doi: 10.1016/j.peptides.2017.12.006. Peptides. 2018. PMID: 29412827 Review.
Furthermore, it seems that like other gut peptides obestatin has neuroprotective properties. This review examines the biochemical properties of the obestatin peptide (its structure, sequence, stability and distribution) and the candidate receptors through which it m …
Furthermore, it seems that like other gut peptides obestatin has neuroprotective properties. This review examines the biochemical pro …
12,751 results
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