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Items: 1 to 20 of 114

1.

Load bearing capacity, fracture mode, and wear performance of digitally veneered full-ceramic single crowns.

Schubert O, Nold E, Obermeier M, Erdelt K, Stimmelmayr M, Beuer F.

Int J Comput Dent. 2017;20(3):245-262.

PMID:
28852743
2.

Mechanical performance of cement- and screw-retained all-ceramic single crowns on dental implants.

Obermeier M, Ristow O, Erdelt K, Beuer F.

Clin Oral Investig. 2017 Jul 15. doi: 10.1007/s00784-017-2178-z. [Epub ahead of print]

PMID:
28710653
3.

Detection of a genetic footprint of the sofosbuvir resistance-associated substitution S282T after HCV treatment failure.

Walker A, Filke S, Lübke N, Obermeier M, Kaiser R, Häussinger D, Timm J, Bock HH.

Virol J. 2017 Jun 8;14(1):106. doi: 10.1186/s12985-017-0779-4.

4.

Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological Disorders.

Liu Q, Shi Q, Marcoux D, Batt DG, Cornelius L, Qin LY, Ruan Z, Neels J, Beaudoin-Bertrand M, Srivastava AS, Li L, Cherney RJ, Gong H, Watterson SH, Weigelt C, Gillooly KM, McIntyre KW, Xie JH, Obermeier MT, Fura A, Sleczka B, Stefanski K, Fancher RM, Padmanabhan S, Rp T, Kundu I, Rajareddy K, Smith R, Hennan JK, Xing D, Fan J, Levesque PC, Ruan Q, Pitt S, Zhang R, Pedicord D, Pan J, Yarde M, Lu H, Lippy J, Goldstine C, Skala S, Rampulla RA, Mathur A, Gupta A, Arunachalam PN, Sack JS, Muckelbauer JK, Cvijic ME, Salter-Cid LM, Bhide RS, Poss MA, Hynes J, Carter PH, Macor JE, Ruepp S, Schieven GL, Tino JA.

J Med Chem. 2017 Jun 22;60(12):5193-5208. doi: 10.1021/acs.jmedchem.7b00618. Epub 2017 Jun 5.

PMID:
28541707
5.

Add-on Antidepressants in the Naturalistic Treatment of Schizophrenia Spectrum Disorder - When, Who, and How?

Schennach R, Obermeier M, Seemüller F, Jäger M, Schmauss M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Spellmann I, Musil R, Möller HJ, Riedel M.

Pharmacopsychiatry. 2017 Jul;50(4):136-144. doi: 10.1055/s-0043-106436. Epub 2017 May 15.

PMID:
28505669
6.

Associations of NEUROD2 polymorphisms and change of cognitive dysfunctions in schizophrenia and schizoaffective disorder after eight weeks of antipsychotic treatment.

Spellmann I, Riedel M, Städtler J, Zill P, Obermeier M, Cerovecki A, Dehning S, Schennach R, Epple M, Opgen-Rhein M, Müller N, Bondy B, Möller HJ, Musil R.

Cogn Neuropsychiatry. 2017 Jul;22(4):280-297. doi: 10.1080/13546805.2017.1322502. Epub 2017 May 4.

PMID:
28470106
7.

HIV-positive men who have sex with men are at high risk of development of significant liver fibrosis after an episode of acute hepatitis C.

Steininger K, Boyd A, Dupke S, Krznaric I, Carganico A, Munteanu M, Neifer S, Schuetze M, Obermeier M, Arasteh K, Baumgarten A, Ingiliz P.

J Viral Hepat. 2017 Oct;24(10):832-839. doi: 10.1111/jvh.12707. Epub 2017 Apr 25.

PMID:
28439936
8.

The role of chromatographic and chiroptical spectroscopic techniques and methodologies in support of drug discovery for atropisomeric drug inhibitors of Bruton's tyrosine kinase.

Dai J, Wang C, Traeger SC, Discenza L, Obermeier MT, Tymiak AA, Zhang Y.

J Chromatogr A. 2017 Mar 3;1487:116-128. doi: 10.1016/j.chroma.2017.01.016. Epub 2017 Jan 6.

PMID:
28131592
9.

[2.2.1]-Bicyclic sultams as potent androgen receptor antagonists.

Shan W, Balog A, Nation A, Zhu X, Chen J, Cvijic ME, Geng J, Rizzo CA, Spires T Jr, Attar RM, Obermeier M, Traeger S, Dai J, Zhang Y, Galella M, Trainor G, Vite GD, Gavai AV.

Bioorg Med Chem Lett. 2016 Dec 1;26(23):5707-5711. doi: 10.1016/j.bmcl.2016.10.059. Epub 2016 Oct 21.

PMID:
27836399
10.

Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton's Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers.

Watterson SH, De Lucca GV, Shi Q, Langevine CM, Liu Q, Batt DG, Beaudoin Bertrand M, Gong H, Dai J, Yip S, Li P, Sun D, Wu DR, Wang C, Zhang Y, Traeger SC, Pattoli MA, Skala S, Cheng L, Obermeier MT, Vickery R, Discenza LN, D'Arienzo CJ, Zhang Y, Heimrich E, Gillooly KM, Taylor TL, Pulicicchio C, McIntyre KW, Galella MA, Tebben AJ, Muckelbauer JK, Chang C, Rampulla R, Mathur A, Salter-Cid L, Barrish JC, Carter PH, Fura A, Burke JR, Tino JA.

J Med Chem. 2016 Oct 13;59(19):9173-9200. Epub 2016 Sep 19.

PMID:
27583770
11.

Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BMS-935177).

De Lucca GV, Shi Q, Liu Q, Batt DG, Beaudoin Bertrand M, Rampulla R, Mathur A, Discenza L, D'Arienzo C, Dai J, Obermeier M, Vickery R, Zhang Y, Yang Z, Marathe P, Tebben AJ, Muckelbauer JK, Chang CJ, Zhang H, Gillooly K, Taylor T, Pattoli MA, Skala S, Kukral DW, McIntyre KW, Salter-Cid L, Fura A, Burke JR, Barrish JC, Carter PH, Tino JA.

J Med Chem. 2016 Sep 8;59(17):7915-35. doi: 10.1021/acs.jmedchem.6b00722. Epub 2016 Aug 26.

PMID:
27531604
12.

Oxytocin course over pregnancy and postpartum period and the association with postpartum depressive symptoms.

Jobst A, Krause D, Maiwald C, Härtl K, Myint AM, Kästner R, Obermeier M, Padberg F, Brücklmeier B, Weidinger E, Kieper S, Schwarz M, Zill P, Müller N.

Arch Womens Ment Health. 2016 Aug;19(4):571-9. doi: 10.1007/s00737-016-0644-2. Epub 2016 Jun 20.

PMID:
27320943
13.

Stability of remission rates in a 3-year follow-up of naturalistic treated depressed inpatients.

Seemüller F, Obermeier M, Schennach R, Bauer M, Adli M, Brieger P, Laux G, Riedel M, Falkai P, Möller HJ.

BMC Psychiatry. 2016 May 20;16:153. doi: 10.1186/s12888-016-0851-4.

14.

Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents.

Kalaghatgi P, Sikorski AM, Knops E, Rupp D, Sierra S, Heger E, Neumann-Fraune M, Beggel B, Walker A, Timm J, Walter H, Obermeier M, Kaiser R, Bartenschlager R, Lengauer T.

PLoS One. 2016 May 19;11(5):e0155869. doi: 10.1371/journal.pone.0155869. eCollection 2016.

15.

Persisting hepatitis E virus infection leading to liver cirrhosis despite recovery of the immune system in an HIV-infected patient.

Ingiliz P, Mayr C, Obermeier M, Herbst H, Polywka S, Pischke S.

Clin Res Hepatol Gastroenterol. 2016 Jun;40(3):e23-e25. doi: 10.1016/j.clinre.2016.01.005. Epub 2016 Apr 4.

PMID:
27055386
16.

Bioprospecting plant-associated microbiomes.

Müller CA, Obermeier MM, Berg G.

J Biotechnol. 2016 Oct 10;235:171-80. doi: 10.1016/j.jbiotec.2016.03.033. Epub 2016 Mar 22. Review.

PMID:
27015976
17.

Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer.

Huang A, Jayaraman L, Fura A, Vite GD, Trainor GL, Gottardis MM, Spires TE, Spires VM, Rizzo CA, Obermeier MT, Elzinga PA, Todderud G, Fan Y, Newitt JA, Beyer SM, Zhu Y, Warrack BM, Goodenough AK, Tebben AJ, Doweyko AM, Gold DL, Balog A.

ACS Med Chem Lett. 2015 Dec 2;7(1):40-5. doi: 10.1021/acsmedchemlett.5b00310. eCollection 2016 Jan 14.

18.

The enzymatic and antioxidative stress response of Lemna minor to copper and a chloroacetamide herbicide.

Obermeier M, Schröder CA, Helmreich B, Schröder P.

Environ Sci Pollut Res Int. 2015 Dec;22(23):18495-507. doi: 10.1007/s11356-015-5139-6. Epub 2015 Aug 20.

PMID:
26286797
20.

HIV-2EU-Supporting Standardized HIV-2 Drug-Resistance Interpretation in Europe: An Update.

Charpentier C, Camacho R, Ruelle J, Eberle J, Gürtler L, Pironti A, Stürmer M, Brun-Vézinet F, Kaiser R, Descamps D, Obermeier M.

Clin Infect Dis. 2015 Oct 15;61(8):1346-7. doi: 10.1093/cid/civ572. Epub 2015 Jul 17. No abstract available.

PMID:
26187019

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