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Items: 1 to 20 of 55

1.

Regulation of osteoarthritis-associated key mediators by TNFα and IL-10: effects of IL-10 overexpression in human synovial fibroblasts and a synovial cell line.

Mrosewski I, Jork N, Gorte K, Conrad C, Wiegand E, Kohl B, Ertel W, John T, Oberholzer A, Kaps C, Schulze-Tanzil G.

Cell Tissue Res. 2014 Jul;357(1):207-23. doi: 10.1007/s00441-014-1868-y. Epub 2014 May 10.

PMID:
24816983
2.

3,6-Diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles are selective inhibitors of Plasmodium falciparum glycogen synthase kinase-3.

Fugel W, Oberholzer AE, Gschloessl B, Dzikowski R, Pressburger N, Preu L, Pearl LH, Baratte B, Ratin M, Okun I, Doerig C, Kruggel S, Lemcke T, Meijer L, Kunick C.

J Med Chem. 2013 Jan 10;56(1):264-75. doi: 10.1021/jm301575n. Epub 2012 Dec 27.

PMID:
23214499
3.

Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.

Tahtouh T, Elkins JM, Filippakopoulos P, Soundararajan M, Burgy G, Durieu E, Cochet C, Schmid RS, Lo DC, Delhommel F, Oberholzer AE, Pearl LH, Carreaux F, Bazureau JP, Knapp S, Meijer L.

J Med Chem. 2012 Nov 8;55(21):9312-30. doi: 10.1021/jm301034u. Epub 2012 Oct 8.

PMID:
22998443
4.

Phosphoenolpyruvate: sugar phosphotransferase system from the hyperthermophilic Thermoanaerobacter tengcongensis.

Navdaeva V, Zurbriggen A, Waltersperger S, Schneider P, Oberholzer AE, Bähler P, Bächler C, Grieder A, Baumann U, Erni B.

Biochemistry. 2011 Feb 22;50(7):1184-93. doi: 10.1021/bi101721f. Epub 2011 Jan 20.

PMID:
21250658
5.

Structure and function of CinD (YtjD) of Lactococcus lactis, a copper-induced nitroreductase involved in defense against oxidative stress.

Mermod M, Mourlane F, Waltersperger S, Oberholzer AE, Baumann U, Solioz M.

J Bacteriol. 2010 Aug;192(16):4172-80. doi: 10.1128/JB.00372-10. Epub 2010 Jun 18.

6.

Crystal structure of enzyme I of the phosphoenolpyruvate sugar phosphotransferase system in the dephosphorylated state.

Oberholzer AE, Schneider P, Siebold C, Baumann U, Erni B.

J Biol Chem. 2009 Nov 27;284(48):33169-76. doi: 10.1074/jbc.M109.057612. Epub 2009 Sep 28.

7.

Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site.

Oberholzer AE, Bumann M, Hege T, Russo S, Baumann U.

Biol Chem. 2009 Sep;390(9):875-81. doi: 10.1515/BC.2009.100.

PMID:
19558324
8.

IL-10 overexpression differentially affects cartilage matrix gene expression in response to TNF-alpha in human articular chondrocytes in vitro.

Müller RD, John T, Kohl B, Oberholzer A, Gust T, Hostmann A, Hellmuth M, Laface D, Hutchins B, Laube G, Veh RW, Tschoeke SK, Ertel W, Schulze-Tanzil G.

Cytokine. 2008 Dec;44(3):377-85. doi: 10.1016/j.cyto.2008.10.012. Epub 2008 Nov 20.

PMID:
19026560
9.

Endogenous IL-10 regulates sepsis-induced thymic apoptosis and improves survival in septic IL-10 null mice.

Tschoeke SK, Oberholzer C, LaFace D, Hutchins B, Moldawer LL, Oberholzer A.

Scand J Immunol. 2008 Dec;68(6):565-71. doi: 10.1111/j.1365-3083.2008.02176.x. Epub 2008 Oct 8.

10.

Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions.

Schütz P, Bumann M, Oberholzer AE, Bieniossek C, Trachsel H, Altmann M, Baumann U.

Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9564-9. doi: 10.1073/pnas.0800418105. Epub 2008 Jul 7.

11.

Impaired erythropoiesis after haemorrhagic shock in mice is associated with erythroid progenitor apoptosis in vivo.

Robinson Y, Matenov A, Tschöke SK, Weimann A, Oberholzer A, Ertel W, Hostmann A.

Acta Anaesthesiol Scand. 2008 May;52(5):605-13. doi: 10.1111/j.1399-6576.2008.01656.x.

PMID:
18419713
12.

Apoptosis of human intervertebral discs after trauma compares to degenerated discs involving both receptor-mediated and mitochondrial-dependent pathways.

Tschoeke SK, Hellmuth M, Hostmann A, Robinson Y, Ertel W, Oberholzer A, Heyde CE.

J Orthop Res. 2008 Jul;26(7):999-1006. doi: 10.1002/jor.20601.

13.

Biphasic onset of splenic apoptosis following hemorrhagic shock: critical implications for Bax, Bcl-2, and Mcl-1 proteins.

Hostmann A, Jasse K, Schulze-Tanzil G, Robinson Y, Oberholzer A, Ertel W, Tschoeke SK.

Crit Care. 2008;12(1):R8. doi: 10.1186/cc6772. Epub 2008 Jan 22.

14.

Interleukin-10 modulates pro-apoptotic effects of TNF-alpha in human articular chondrocytes in vitro.

John T, Müller RD, Oberholzer A, Zreiqat H, Kohl B, Ertel W, Hostmann A, Tschoeke SK, Schulze-Tanzil G.

Cytokine. 2007 Dec;40(3):226-34. Epub 2007 Nov 19.

PMID:
18023359
15.

The early second hit in trauma management augments the proinflammatory immune response to multiple injuries.

Tschoeke SK, Hellmuth M, Hostmann A, Ertel W, Oberholzer A.

J Trauma. 2007 Jun;62(6):1396-403; discussion 1403-4.

PMID:
17563655
16.

[Gene therapy for treatment of acute inflammatory immune response].

Tschöke SK, Oberholzer A.

Orthopade. 2007 Mar;36(3):259-64. Review. German.

PMID:
17333067
17.

Adenoviral transduction is more efficient in alginate-derived chondrocytes than in monolayer chondrocytes.

Oberholzer A, John T, Kohl B, Gust T, Müller RD, La Face D, Hutchins B, Zreiqat H, Ertel W, Schulze-Tanzil G.

Cell Tissue Res. 2007 May;328(2):383-90. Epub 2007 Jan 30.

PMID:
17265065
18.

Erythropoiesis in multiply injured patients.

Robinson Y, Hostmann A, Matenov A, Ertel W, Oberholzer A.

J Trauma. 2006 Nov;61(5):1285-91. Review.

PMID:
17099548
19.

Concepts of transtibial amputation: Burgess technique versus modified Brückner procedure.

Stahel PF, Oberholzer A, Morgan SJ, Heyde CE.

ANZ J Surg. 2006 Oct;76(10):942-6. Review.

PMID:
17007627
20.

Traumatic proximal tibiofibular joint dislocation treated by open reduction and temporary fixation: a case report.

Robinson Y, Reinke M, Heyde CE, Ertel W, Oberholzer A.

Knee Surg Sports Traumatol Arthrosc. 2007 Feb;15(2):199-201. Epub 2006 Jul 21.

PMID:
16858561

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