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Items: 17


Design and synthesis of potent and orally active GPR4 antagonists with modulatory effects on nociception, inflammation, and angiogenesis.

Miltz W, Velcicky J, Dawson J, Littlewood-Evans A, Ludwig MG, Seuwen K, Feifel R, Oberhauser B, Meyer A, Gabriel D, Nash M, Loetscher P.

Bioorg Med Chem. 2017 Aug 15;25(16):4512-4525. doi: 10.1016/j.bmc.2017.06.050. Epub 2017 Jun 29.


Development of Selective, Orally Active GPR4 Antagonists with Modulatory Effects on Nociception, Inflammation, and Angiogenesis.

Velcicky J, Miltz W, Oberhauser B, Orain D, Vaupel A, Weigand K, Dawson King J, Littlewood-Evans A, Nash M, Feifel R, Loetscher P.

J Med Chem. 2017 May 11;60(9):3672-3683. doi: 10.1021/acs.jmedchem.6b01703. Epub 2017 Apr 26.


Orally active 7-substituted (4-benzylphthalazin-1-yl)-2-methylpiperazin-1-yl]nicotinonitriles as active-site inhibitors of sphingosine 1-phosphate lyase for the treatment of multiple sclerosis.

Weiler S, Braendlin N, Beerli C, Bergsdorf C, Schubart A, Srinivas H, Oberhauser B, Billich A.

J Med Chem. 2014 Jun 26;57(12):5074-84. doi: 10.1021/jm500338n. Epub 2014 May 21.


Sequence analysis for detection of first-line drug resistance in Mycobacterium tuberculosis strains from a high-incidence setting.

Feuerriegel S, Oberhauser B, George AG, Dafae F, Richter E, Rüsch-Gerdes S, Niemann S.

BMC Microbiol. 2012 May 30;12:90. doi: 10.1186/1471-2180-12-90.


Targeting ceramide metabolism with a potent and specific ceramide kinase inhibitor.

Graf C, Klumpp M, Habig M, Rovina P, Billich A, Baumruker T, Oberhauser B, Bornancin F.

Mol Pharmacol. 2008 Oct;74(4):925-32. doi: 10.1124/mol.108.048652. Epub 2008 Jul 8.


High genetic diversity among Mycobacterium tuberculosis complex strains from Sierra Leone.

Homolka S, Post E, Oberhauser B, George AG, Westman L, Dafae F, Rüsch-Gerdes S, Niemann S.

BMC Microbiol. 2008 Jun 25;8:103. doi: 10.1186/1471-2180-8-103.


Inhibition of vascular endothelial growth factor cotranslational translocation by the cyclopeptolide CAM741.

Harant H, Wolff B, Schreiner EP, Oberhauser B, Hofer L, Lettner N, Maier S, de Vries JE, Lindley IJ.

Mol Pharmacol. 2007 Jun;71(6):1657-65. Epub 2007 Mar 16.


The translocation inhibitor CAM741 interferes with vascular cell adhesion molecule 1 signal peptide insertion at the translocon.

Harant H, Lettner N, Hofer L, Oberhauser B, de Vries JE, Lindley IJ.

J Biol Chem. 2006 Oct 13;281(41):30492-502. Epub 2006 Aug 16.


Tuberculosis after HAART initiation in HIV-positive patients from five countries with a high tuberculosis burden.

Bonnet MM, Pinoges LL, Varaine FF, Oberhauser BB, O'Brien DD, Kebede YY, Hewison CC, Zachariah RR, Ferradini LL.

AIDS. 2006 Jun 12;20(9):1275-9.


Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1.

Besemer J, Harant H, Wang S, Oberhauser B, Marquardt K, Foster CA, Schreiner EP, de Vries JE, Dascher-Nadel C, Lindley IJ.

Nature. 2005 Jul 14;436(7048):290-3.


The 3D-structure of a natural inhibitor of cell adhesion molecule expression.

Hommel U, Weber HP, Oberer L, Naegeli HU, Oberhauser B, Foster CA.

FEBS Lett. 1996 Jan 22;379(1):69-73.


The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems.

Plank C, Oberhauser B, Mechtler K, Koch C, Wagner E.

J Biol Chem. 1994 Apr 29;269(17):12918-24.


A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites.

Wagner E, Oberhauser B, Holzner A, Brunar H, Issakides G, Schaffner G, Cotten M, Knollmüller M, Noe CR.

Nucleic Acids Res. 1991 Nov 11;19(21):5965-71.


2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event.

Cotten M, Oberhauser B, Brunar H, Holzner A, Issakides G, Noe CR, Schaffner G, Wagner E, Birnstiel ML.

Nucleic Acids Res. 1991 May 25;19(10):2629-35.


[Sports and diet--an ambulatory program for obese children].

Korsten-Reck U, Müller H, Oberhauser B, Rokitzki L, Keul J.

Offentl Gesundheitswes. 1990 Aug-Sep;52(8-9):441-7. German.


[Prevention and therapy of obesity with diet and sports, an ambulatory therapy program for overweight children].

Korsten-Reck U, Müller H, Pokan R, Huonker M, Berg A, Oberhauser B, Rokitzki L, Keul J.

Wien Med Wochenschr. 1990 May 15;140(9):232-40. Review. German.


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