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Items: 1 to 20 of 181

1.

A BAHD acyltransferase catalyzing 19-O-acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids.

Carqueijeiro I, Dugé de Bernonville T, Lanoue A, Dang TT, Teijaro C, Paetz C, Billet K, Mosquera A, Oudin A, Besseau S, Papon N, Glévarec G, Atehortùa L, Clastre M, Giglioli-Guivarc'h N, Schneider B, St-Pierre B, Andrade RB, O'Connor SE, Courdavault V.

Plant J. 2018 Feb 13. doi: 10.1111/tpj.13868. [Epub ahead of print]

PMID:
29438577
2.

Raising the BAR of specificity.

O'Connor SE.

Nat Plants. 2017 Dec;3(12):924-925. doi: 10.1038/s41477-017-0074-9. No abstract available.

PMID:
29180812
3.

Identification of iridoid synthases from Nepeta species: Iridoid cyclization does not determine nepetalactone stereochemistry.

Sherden NH, Lichman B, Caputi L, Zhao D, Kamileen MO, Buell CR, O'Connor SE.

Phytochemistry. 2018 Jan;145:48-56. doi: 10.1016/j.phytochem.2017.10.004. Epub 2017 Nov 5.

4.

Identification of Iridoid Glucoside Transporters in Catharanthus roseus.

Larsen B, Fuller VL, Pollier J, Van Moerkercke A, Schweizer F, Payne R, Colinas M, O'Connor SE, Goossens A, Halkier BA.

Plant Cell Physiol. 2017 Sep 1;58(9):1507-1518. doi: 10.1093/pcp/pcx097.

PMID:
28922750
5.

A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate.

Tatsis EC, Carqueijeiro I, Dugé de Bernonville T, Franke J, Dang TT, Oudin A, Lanoue A, Lafontaine F, Stavrinides AK, Clastre M, Courdavault V, O'Connor SE.

Nat Commun. 2017 Aug 22;8(1):316. doi: 10.1038/s41467-017-00154-x.

6.

Inverted stereocontrol of iridoid synthase in snapdragon.

Kries H, Kellner F, Kamileen MO, O'Connor SE.

J Biol Chem. 2017 Sep 1;292(35):14659-14667. doi: 10.1074/jbc.M117.800979. Epub 2017 Jul 12.

7.

Dual Catalytic Activity of a Cytochrome P450 Controls Bifurcation at a Metabolic Branch Point of Alkaloid Biosynthesis in Rauwolfia serpentina.

Dang TT, Franke J, Tatsis E, O'Connor SE.

Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9440-9444. doi: 10.1002/anie.201705010. Epub 2017 Jul 12.

8.

Differential iridoid production as revealed by a diversity panel of 84 cultivated and wild blueberry species.

Leisner CP, Kamileen MO, Conway ME, O'Connor SE, Buell CR.

PLoS One. 2017 Jun 13;12(6):e0179417. doi: 10.1371/journal.pone.0179417. eCollection 2017.

9.

Folivory elicits a strong defense reaction in Catharanthus roseus: metabolomic and transcriptomic analyses reveal distinct local and systemic responses.

Dugé de Bernonville T, Carqueijeiro I, Lanoue A, Lafontaine F, Sánchez Bel P, Liesecke F, Musset K, Oudin A, Glévarec G, Pichon O, Besseau S, Clastre M, St-Pierre B, Flors V, Maury S, Huguet E, O'Connor SE, Courdavault V.

Sci Rep. 2017 Jan 17;7:40453. doi: 10.1038/srep40453.

10.

An NPF transporter exports a central monoterpene indole alkaloid intermediate from the vacuole.

Payne RM, Xu D, Foureau E, Teto Carqueijeiro MI, Oudin A, Bernonville TD, Novak V, Burow M, Olsen CE, Jones DM, Tatsis EC, Pendle A, Ann Halkier B, Geu-Flores F, Courdavault V, Nour-Eldin HH, O'Connor SE.

Nat Plants. 2017 Jan 13;3:16208. doi: 10.1038/nplants.2016.208.

11.

Structural characterization of EasH (Aspergillus japonicus) - an oxidase involved in cycloclavine biosynthesis.

Jakubczyk D, Caputi L, Stevenson CE, Lawson DM, O'Connor SE.

Chem Commun (Camb). 2016 Dec 6;52(99):14306-14309.

12.

Class II Cytochrome P450 Reductase Governs the Biosynthesis of Alkaloids.

Parage C, Foureau E, Kellner F, Burlat V, Mahroug S, Lanoue A, Dugé de Bernonville T, Londono MA, Carqueijeiro I, Oudin A, Besseau S, Papon N, Glévarec G, Atehortùa L, Giglioli-Guivarc'h N, St-Pierre B, Clastre M, O'Connor SE, Courdavault V.

Plant Physiol. 2016 Nov;172(3):1563-1577. Epub 2016 Sep 29.

13.

Preface.

O'Connor SE.

Methods Enzymol. 2016;576:xvii-xviii. doi: 10.1016/S0076-6879(16)30186-0. No abstract available.

PMID:
27480694
14.

Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity.

Stavrinides A, Tatsis EC, Caputi L, Foureau E, Stevenson CE, Lawson DM, Courdavault V, O'Connor SE.

Nat Commun. 2016 Jul 15;7:12116. doi: 10.1038/ncomms12116.

15.

Preface.

O'Connor SE.

Methods Enzymol. 2016;575:xv-xvi. doi: 10.1016/S0076-6879(16)30172-0. No abstract available.

PMID:
27417936
16.

New developments in engineering plant metabolic pathways.

Tatsis EC, O'Connor SE.

Curr Opin Biotechnol. 2016 Dec;42:126-132. doi: 10.1016/j.copbio.2016.04.012. Epub 2016 Apr 29. Review.

17.

Biocatalysts from alkaloid producing plants.

Kries H, O'Connor SE.

Curr Opin Chem Biol. 2016 Apr;31:22-30. doi: 10.1016/j.cbpa.2015.12.006. Epub 2016 Jan 13. Review.

18.

Identification and Characterization of the Iridoid Synthase Involved in Oleuropein Biosynthesis in Olive (Olea europaea) Fruits.

Alagna F, Geu-Flores F, Kries H, Panara F, Baldoni L, O'Connor SE, Osbourn A.

J Biol Chem. 2016 Mar 11;291(11):5542-54. doi: 10.1074/jbc.M115.701276. Epub 2015 Dec 26.

19.

Structural determinants of reductive terpene cyclization in iridoid biosynthesis.

Kries H, Caputi L, Stevenson CEM, Kamileen MO, Sherden NH, Geu-Flores F, Lawson DM, O'Connor SE.

Nat Chem Biol. 2016 Jan;12(1):6-8. doi: 10.1038/nchembio.1955. Epub 2015 Nov 9.

20.

Weight Status in the First 2 Years of Life and Neurodevelopmental Impairment in Extremely Low Gestational Age Newborns.

Belfort MB, Kuban KC, O'Shea TM, Allred EN, Ehrenkranz RA, Engelke SC, Leviton A; Extremely Low Gestational Age Newborn (ELGAN) Study Investigators; Extremely Low Gestational Age Newborn ELGAN Study Investigators.

J Pediatr. 2016 Jan;168:30-5.e2. doi: 10.1016/j.jpeds.2015.09.036. Epub 2015 Oct 21.

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