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Items: 1 to 20 of 37


Long non-coding RNA PARTICLE bridges histone and DNA methylation.

O'Leary VB, Hain S, Maugg D, Smida J, Azimzadeh O, Tapio S, Ovsepian SV, Atkinson MJ.

Sci Rep. 2017 May 11;7(1):1790. doi: 10.1038/s41598-017-01875-1.


Genome-wide analysis of somatic copy number alterations and chromosomal breakages in osteosarcoma.

Smida J, Xu H, Zhang Y, Baumhoer D, Ribi S, Kovac M, von Luettichau I, Bielack S, O'Leary VB, Leib-Mösch C, Frishman D, Nathrath M.

Int J Cancer. 2017 Aug 15;141(4):816-828. doi: 10.1002/ijc.30778. Epub 2017 May 25.


Low-Affinity Neurotrophin Receptor p75 Promotes the Transduction of Targeted Lentiviral Vectors to Cholinergic Neurons of Rat Basal Forebrain.

Antyborzec I, O'Leary VB, Dolly JO, Ovsepian SV.

Neurotherapeutics. 2016 Oct;13(4):859-870.


Circumventing Brain Barriers: Nanovehicles for Retroaxonal Therapeutic Delivery.

Ovsepian SV, O'Leary VB, Ntziachristos V, Dolly JO.

Trends Mol Med. 2016 Nov;22(11):983-993. doi: 10.1016/j.molmed.2016.09.004. Epub 2016 Oct 5. Review.


Distinctive role of KV1.1 subunit in the biology and functions of low threshold K(+) channels with implications for neurological disease.

Ovsepian SV, LeBerre M, Steuber V, O'Leary VB, Leibold C, Oliver Dolly J.

Pharmacol Ther. 2016 Mar;159:93-101. doi: 10.1016/j.pharmthera.2016.01.005. Epub 2016 Jan 26. Review.


Neuronal activity and amyloid plaque pathology: an update.

Ovsepian SV, O'Leary VB.

J Alzheimers Dis. 2016;49(1):13-9. doi: 10.3233/JAD-150544. Review.


Cholinergic Mechanisms in the Cerebral Cortex: Beyond Synaptic Transmission.

Ovsepian SV, O'Leary VB, Zaborszky L.

Neuroscientist. 2016 Jun;22(3):238-51. doi: 10.1177/1073858415588264. Epub 2015 May 22.


PARTICLE, a Triplex-Forming Long ncRNA, Regulates Locus-Specific Methylation in Response to Low-Dose Irradiation.

O'Leary VB, Ovsepian SV, Carrascosa LG, Buske FA, Radulovic V, Niyazi M, Moertl S, Trau M, Atkinson MJ, Anastasov N.

Cell Rep. 2015 Apr 21;11(3):474-85.


Erratum to: Internalization and retrograde axonal trafficking of tetanus toxin in motor neurons and trans-synaptic propagation at central synapses exceed those of its C-terminal-binding fragments.

Ovsepian SV, Bodeker M, O'Leary VB, Lawrence GW, Oliver Dolly J.

Brain Struct Funct. 2015 May;220(3):1839. doi: 10.1007/s00429-015-1030-y. No abstract available.


Glucose and lipopolysaccharide regulate proatherogenic cytokine release from mononuclear cells in polycystic ovary syndrome.

González F, Kirwan JP, Rote NS, Minium J, O'Leary VB.

J Reprod Immunol. 2014 Jun;103:38-44. doi: 10.1016/j.jri.2014.01.001. Epub 2014 Feb 2.


Disruption of myelin leads to ectopic expression of K(V)1.1 channels with abnormal conductivity of optic nerve axons in a cuprizone-induced model of demyelination.

Bagchi B, Al-Sabi A, Kaza S, Scholz D, O'Leary VB, Dolly JO, Ovsepian SV.

PLoS One. 2014 Feb 3;9(2):e87736. doi: 10.1371/journal.pone.0087736. eCollection 2014.


Improved lentiviral transduction of ALS motoneurons in vivo via dual targeting.

O'Leary VB, Ovsepian SV, Bodeker M, Dolly JO.

Mol Pharm. 2013 Nov 4;10(11):4195-206. doi: 10.1021/mp400247t. Epub 2013 Oct 11.


Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Aβ) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons.

Ovsepian SV, Antyborzec I, O'Leary VB, Zaborszky L, Herms J, Oliver Dolly J.

Brain Struct Funct. 2014 Sep;219(5):1527-41. doi: 10.1007/s00429-013-0583-x. Epub 2013 May 29.


A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets.

Ovsepian SV, Steuber V, Le Berre M, O'Hara L, O'Leary VB, Dolly JO.

J Physiol. 2013 Apr 1;591(7):1771-91. doi: 10.1113/jphysiol.2012.249706. Epub 2013 Jan 14.


Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects.

Pangilinan F, Molloy AM, Mills JL, Troendle JF, Parle-McDermott A, Signore C, O'Leary VB, Chines P, Seay JM, Geiler-Samerotte K, Mitchell A, VanderMeer JE, Krebs KM, Sanchez A, Cornman-Homonoff J, Stone N, Conley M, Kirke PN, Shane B, Scott JM, Brody LC.

BMC Med Genet. 2012 Aug 2;13:62.


Innocuous full-length botulinum neurotoxin targets and promotes the expression of lentiviral vectors in central and autonomic neurons.

O'Leary VB, Ovsepian SV, Raghunath A, Huo Q, Lawrence GW, Smith L, Dolly JO.

Gene Ther. 2011 Jul;18(7):656-65. doi: 10.1038/gt.2011.8. Epub 2011 Mar 3.


Retinol-binding protein 4 (RBP4) protein expression is increased in omental adipose tissue of severely obese patients.

Kelly KR, Kashyap SR, O'Leary VB, Major J, Schauer PR, Kirwan JP.

Obesity (Silver Spring). 2010 Apr;18(4):663-6. doi: 10.1038/oby.2009.328. Epub 2009 Oct 8.


Decreased visfatin after exercise training correlates with improved glucose tolerance.

Haus JM, Solomon TP, Marchetti CM, O'Leary VB, Brooks LM, Gonzalez F, Kirwan JP.

Med Sci Sports Exerc. 2009 Jun;41(6):1255-60. doi: 10.1249/MSS.0b013e318195bad5.


The glucose-dependent insulinotropic polypeptide and glucose-stimulated insulin response to exercise training and diet in obesity.

Kelly KR, Brooks LM, Solomon TP, Kashyap SR, O'Leary VB, Kirwan JP.

Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1269-74. doi: 10.1152/ajpendo.00112.2009. Epub 2009 Apr 7.

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