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Items: 1 to 20 of 40


Identification and optimization of an aminoalcohol-carbazole series with antimalarial properties.

Molette J, Routier J, Abla N, Besson D, Bombrun A, Brun R, Burt H, Georgi K, Kaiser M, Nwaka S, Muzerelle M, Scheer A.

ACS Med Chem Lett. 2013 Sep 22;4(11):1037-41. doi: 10.1021/ml400015f. eCollection 2013 Nov 14.


Analysis of pan-African Centres of excellence in health innovation highlights opportunities and challenges for local innovation and financing in the continent.

Nwaka S, Ochem A, Besson D, Ramirez B, Fakorede F, Botros S, Inyang U, Mgone C, Adae-Mensah I, Konde V, Nyasse B, Okole B, Guantai A, Loots G, Atadja P, Ndumbe P, Sanou I, Olesen O, Ridley R, Ilunga T.

BMC Int Health Hum Rights. 2012 Jul 27;12:11. doi: 10.1186/1472-698X-12-11.


Perspectives: The missing pieces.

Crabb BS, Beeson JG, Amino R, Ménard R, Waters A, Winzeler EA, Wahlgren M, Fidock DA, Nwaka S.

Nature. 2012 Apr 25;484(7395):S22-3. doi: 10.1038/484S22a. No abstract available.


Integrated dataset of screening hits against multiple neglected disease pathogens.

Nwaka S, Besson D, Ramirez B, Maes L, Matheeussen A, Bickle Q, Mansour NR, Yousif F, Townson S, Gokool S, Cho-Ngwa F, Samje M, Misra-Bhattacharya S, Murthy PK, Fakorede F, Paris JM, Yeates C, Ridley R, Van Voorhis WC, Geary T.

PLoS Negl Trop Dis. 2011 Dec;5(12):e1412. doi: 10.1371/journal.pntd.0001412. Epub 2011 Dec 20.


Innovative partnerships for drug discovery against neglected diseases.

Jakobsen PH, Wang MW, Nwaka S.

PLoS Negl Trop Dis. 2011 Sep;5(9):e1221. doi: 10.1371/journal.pntd.0001221. Epub 2011 Sep 27. No abstract available.


Drugs and diagnostic innovations to improve global health.

Peeling RW, Nwaka S.

Infect Dis Clin North Am. 2011 Sep;25(3):693-705, xi. doi: 10.1016/j.idc.2011.06.002.


Interview with Solomon Nwaka.

Nwaka S.

Future Med Chem. 2011 Sep;3(11):1339-44. doi: 10.4155/fmc.11.99.


Traditional medicines as a mechanism for driving research innovation in Africa.

Addae-Mensah I, Fakorede F, Holtel A, Nwaka S.

Malar J. 2011 Mar 15;10 Suppl 1:S9. doi: 10.1186/1475-2875-10-S1-S9. Review.


A research agenda for malaria eradication: drugs.

malERA Consultative Group on Drugs.

PLoS Med. 2011 Jan 25;8(1):e1000402. doi: 10.1371/journal.pmed.1000402. Review.


Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.

Crowther GJ, Shanmugam D, Carmona SJ, Doyle MA, Hertz-Fowler C, Berriman M, Nwaka S, Ralph SA, Roos DS, Van Voorhis WC, Agüero F.

PLoS Negl Trop Dis. 2010 Aug 24;4(8):e804. doi: 10.1371/journal.pntd.0000804.


CRIMALDDI: a co-ordinated, rational, and integrated effort to set logical priorities in anti-malarial drug discovery initiatives.

Boulton IC, Nwaka S, Bathurst I, Lanzer M, Taramelli D, Vial H, Doerig C, Chibale K, Ward SA.

Malar J. 2010 Jul 13;9:202. doi: 10.1186/1475-2875-9-202.


Developing ANDI: a novel approach to health product R&D in Africa.

Nwaka S, Ilunga TB, Da Silva JS, Rial Verde E, Hackley D, De Vré R, Mboya-Okeyo T, Ridley RG.

PLoS Med. 2010 Jun 29;7(6):e1000293. doi: 10.1371/journal.pmed.1000293. No abstract available.


Synthesis and structure-activity relationships of antimalarial 4-oxo-3-carboxyl quinolones.

Zhang Y, Guiguemde WA, Sigal M, Zhu F, Connelly MC, Nwaka S, Guy RK.

Bioorg Med Chem. 2010 Apr 1;18(7):2756-66. doi: 10.1016/j.bmc.2010.02.013. Epub 2010 Feb 11.


Advancing drug innovation for neglected diseases-criteria for lead progression.

Nwaka S, Ramirez B, Brun R, Maes L, Douglas F, Ridley R.

PLoS Negl Trop Dis. 2009 Aug 25;3(8):e440. doi: 10.1371/journal.pntd.0000440.


The African Network for Drugs and Diagnostics Innovation.

Mboya-Okeyo T, Ridley RG, Nwaka S; ANDI Task Force.

Lancet. 2009 May 2;373(9674):1507-8. doi: 10.1016/S0140-6736(09)60838-2. No abstract available.


Genomic-scale prioritization of drug targets: the TDR Targets database.

Agüero F, Al-Lazikani B, Aslett M, Berriman M, Buckner FS, Campbell RK, Carmona S, Carruthers IM, Chan AW, Chen F, Crowther GJ, Doyle MA, Hertz-Fowler C, Hopkins AL, McAllister G, Nwaka S, Overington JP, Pain A, Paolini GV, Pieper U, Ralph SA, Riechers A, Roos DS, Sali A, Shanmugam D, Suzuki T, Van Voorhis WC, Verlinde CL.

Nat Rev Drug Discov. 2008 Nov;7(11):900-7. doi: 10.1038/nrd2684. Epub 2008 Oct 17. Review.


Challenges in drug discovery for novel antifilarials.

Townson S, Ramirez B, Fakorede F, Mouries MA, Nwaka S.

Expert Opin Drug Discov. 2007 Oct;2(s1):S63-73. doi: 10.1517/17460441.2.S1.S63.


Schistosomes: challenges in compound screening.

Ramirez B, Bickle Q, Yousif F, Fakorede F, Mouries MA, Nwaka S.

Expert Opin Drug Discov. 2007 Oct;2(s1):S53-61. doi: 10.1517/17460441.2.S1.S53.


Mission possible.

Hopkins AL, Witty MJ, Nwaka S.

Nature. 2007 Sep 13;449(7159):166-9. No abstract available.


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