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Items: 10


NP108, an antimicrobial polymer with activity against methicillin and mupirocin resistant Staphylococcus aureus.

Mercer DK, Katvars LK, Hewitt F, Smith DW, Robertson J, O'Neil DA.

Antimicrob Agents Chemother. 2017 Jun 12. pii: AAC.00502-17. doi: 10.1128/AAC.00502-17. [Epub ahead of print]


Expression of innate immune defence genes in healthy and onychomycotic nail and stratum corneum.

Mercer DK, Sairi T, Sroka E, Lamont H, Lawrie Y, O'Neil DA.

Br J Dermatol. 2016 Sep 17. doi: 10.1111/bjd.15063. [Epub ahead of print] No abstract available.


Activity of Cysteamine against the Cystic Fibrosis Pathogen Burkholderia cepacia Complex.

Fraser-Pitt D, Mercer D, Lovie E, Robertson J, O'Neil D.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):6200-6. doi: 10.1128/AAC.01198-16. Print 2016 Oct.


An Open-Label Investigation of the Pharmacokinetics and Tolerability of Oral Cysteamine in Adults with Cystic Fibrosis.

Devereux G, Steele S, Griffiths K, Devlin E, Fraser-Pitt D, Cotton S, Norrie J, Chrystyn H, O'Neil D.

Clin Drug Investig. 2016 Aug;36(8):605-12. doi: 10.1007/s40261-016-0405-z.


Cysteamine as a Future Intervention in Cystic Fibrosis Against Current and Emerging Pathogens: A Patient-based ex vivo Study Confirming its Antimicrobial and Mucoactive Potential in Sputum.

Devereux G, Fraser-Pitt D, Robertson J, Devlin E, Mercer D, O'Neil D.

EBioMedicine. 2015 Aug 10;2(10):1507-12. doi: 10.1016/j.ebiom.2015.08.018. eCollection 2015 Oct.


Cystic fibrosis - a multiorgan protein misfolding disease.

Fraser-Pitt D, O'Neil D.

Future Sci OA. 2015 Sep 1;1(2):FSO57. doi: 10.4155/fso.15.57. eCollection 2015 Sep. Review.


Cysteamine (Lynovex®), a novel mucoactive antimicrobial & antibiofilm agent for the treatment of cystic fibrosis.

Charrier C, Rodger C, Robertson J, Kowalczuk A, Shand N, Fraser-Pitt D, Mercer D, O'Neil D.

Orphanet J Rare Dis. 2014 Nov 30;9:189. doi: 10.1186/s13023-014-0189-2.


Progress towards next-generation therapeutics for cystic fibrosis.

O'Neil DA, Fraser-Pitt D.

Future Med Chem. 2014 Jun;6(9):1067-79. doi: 10.4155/fmc.14.67. Review.


A prodrug approach to the use of coumarins as potential therapeutics for superficial mycoses.

Mercer DK, Robertson J, Wright K, Miller L, Smith S, Stewart CS, O Neil DA.

PLoS One. 2013 Nov 18;8(11):e80760. doi: 10.1371/journal.pone.0080760. eCollection 2013.


Peptides as the next generation of anti-infectives.

Mercer DK, O'Neil DA.

Future Med Chem. 2013 Mar;5(3):315-37. doi: 10.4155/fmc.12.213. Review.


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