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Items: 1 to 20 of 291


Impact of AmpC Derepression on Fitness and Virulence: the Mechanism or the Pathway?

Pérez-Gallego M, Torrens G, Castillo-Vera J, Moya B, Zamorano L, Cabot G, Hultenby K, Albertí S, Mellroth P, Henriques-Normark B, Normark S, Oliver A, Juan C.

MBio. 2016 Oct 25;7(5). pii: e01783-16. doi: 10.1128/mBio.01783-16.


Streptococcal M1 Strikes by Neutralizing Cathelicidins.

Henriques-Normark B, Normark S.

Cell Host Microbe. 2015 Oct 14;18(4):390-1. doi: 10.1016/j.chom.2015.10.002.


Uptake of extracellular DNA: competence induced pili in natural transformation of Streptococcus pneumoniae.

Muschiol S, Balaban M, Normark S, Henriques-Normark B.

Bioessays. 2015 Apr;37(4):426-35. doi: 10.1002/bies.201400125. Epub 2015 Jan 15.


Microbial biofilm formation: a need to act.

Römling U, Kjelleberg S, Normark S, Nyman L, Uhlin BE, Åkerlund B.

J Intern Med. 2014 Aug;276(2):98-110. doi: 10.1111/joim.12242. Epub 2014 May 6. Review. No abstract available. Erratum in: J Intern Med. 2015 Oct;278(4):427.


Bacterial vaccines and antibiotic resistance.

Henriques-Normark B, Normark S.

Ups J Med Sci. 2014 May;119(2):205-8. doi: 10.3109/03009734.2014.903324. Epub 2014 Apr 3. Review.


Secretion of a pneumococcal type II secretion system pilus correlates with DNA uptake during transformation.

Balaban M, Bättig P, Muschiol S, Tirier SM, Wartha F, Normark S, Henriques-Normark B.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):E758-65. doi: 10.1073/pnas.1313860111. Epub 2014 Feb 3.


Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae.

Mellroth P, Sandalova T, Kikhney A, Vilaplana F, Hesek D, Lee M, Mobashery S, Normark S, Svergun D, Henriques-Normark B, Achour A.

MBio. 2014 Feb 11;5(1):e01120-13. doi: 10.1128/mBio.01120-13.


Emergence of hypervirulent mutants resistant to early clearance during systemic serotype 1 pneumococcal infection in mice and humans.

Syk A, Norman M, Fernebro J, Gallotta M, Farmand S, Sandgren A, Normark S, Henriques-Normark B.

J Infect Dis. 2014 Jul 1;210(1):4-13. Epub 2014 Jan 16.


The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold.

Schulte T, Löfling J, Mikaelsson C, Kikhney A, Hentrich K, Diamante A, Ebel C, Normark S, Svergun D, Henriques-Normark B, Achour A.

Open Biol. 2014 Jan 15;4:130090. doi: 10.1098/rsob.130090. Erratum in: Open Biol. 2014;4:140172.


Focal targeting by human β-defensin 2 disrupts localized virulence factor assembly sites in Enterococcus faecalis.

Kandaswamy K, Liew TH, Wang CY, Huston-Warren E, Meyer-Hoffert U, Hultenby K, Schröder JM, Caparon MG, Normark S, Henriques-Normark B, Hultgren SJ, Kline KA.

Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20230-5. doi: 10.1073/pnas.1319066110. Epub 2013 Nov 4.


Dominant role of nucleotide substitution in the diversification of serotype 3 pneumococci over decades and during a single infection.

Croucher NJ, Mitchell AM, Gould KA, Inverarity D, Barquist L, Feltwell T, Fookes MC, Harris SR, Dordel J, Salter SJ, Browall S, Zemlickova H, Parkhill J, Normark S, Henriques-Normark B, Hinds J, Mitchell TJ, Bentley SD.

PLoS Genet. 2013;9(10):e1003868. doi: 10.1371/journal.pgen.1003868. Epub 2013 Oct 10.


Intraclonal variations among Streptococcus pneumoniae isolates influence the likelihood of invasive disease in children.

Browall S, Norman M, Tångrot J, Galanis I, Sjöström K, Dagerhamn J, Hellberg C, Pathak A, Spadafina T, Sandgren A, Bättig P, Franzén O, Andersson B, Örtqvist Å, Normark S, Henriques-Normark B.

J Infect Dis. 2014 Feb 1;209(3):377-88. doi: 10.1093/infdis/jit481. Epub 2013 Sep 5.


Pilin and sortase residues critical for endocarditis- and biofilm-associated pilus biogenesis in Enterococcus faecalis.

Nielsen HV, Flores-Mireles AL, Kau AL, Kline KA, Pinkner JS, Neiers F, Normark S, Henriques-Normark B, Caparon MG, Hultgren SJ.

J Bacteriol. 2013 Oct;195(19):4484-95. doi: 10.1128/JB.00451-13. Epub 2013 Aug 2.


Influenza A virus-mediated priming enhances cytokine secretion by human dendritic cells infected with Streptococcus pneumoniae.

Kuri T, Sörensen AS, Thomas S, Karlsson Hedestam GB, Normark S, Henriques-Normark B, McInerney GM, Plant L.

Cell Microbiol. 2013 Aug;15(8):1385-400. doi: 10.1111/cmi.12122. Epub 2013 Mar 14.


Pilus adhesin RrgA interacts with complement receptor 3, thereby affecting macrophage function and systemic pneumococcal disease.

Orrskog S, Rounioja S, Spadafina T, Gallotta M, Norman M, Hentrich K, Fälker S, Ygberg-Eriksson S, Hasenberg M, Johansson B, Uotila LM, Gahmberg CG, Barocchi M, Gunzer M, Normark S, Henriques-Normark B.

MBio. 2012 Dec 26;4(1):e00535-12. doi: 10.1128/mBio.00535-12.


The metal ion-dependent adhesion site motif of the Enterococcus faecalis EbpA pilin mediates pilus function in catheter-associated urinary tract infection.

Nielsen HV, Guiton PS, Kline KA, Port GC, Pinkner JS, Neiers F, Normark S, Henriques-Normark B, Caparon MG, Hultgren SJ.

MBio. 2012 Jul 24;3(4):e00177-12. doi: 10.1128/mBio.00177-12. Print 2012.


LytA, major autolysin of Streptococcus pneumoniae, requires access to nascent peptidoglycan.

Mellroth P, Daniels R, Eberhardt A, Rönnlund D, Blom H, Widengren J, Normark S, Henriques-Normark B.

J Biol Chem. 2012 Mar 30;287(14):11018-29. doi: 10.1074/jbc.M111.318584. Epub 2012 Feb 9.


Impaired release of antimicrobial peptides into nasal fluid of hyper-IgE and CVID patients.

Cederlund A, Olliver M, Rekha RS, Lindh M, Lindbom L, Normark S, Henriques-Normark B, Andersson J, Agerberth B, Bergman P.

PLoS One. 2011;6(12):e29316. doi: 10.1371/journal.pone.0029316. Epub 2011 Dec 27.


A method for metagenomics of Helicobacter pylori from archived formalin-fixed gastric biopsies permitting longitudinal studies of carcinogenic risk.

Zheng Z, Andersson AF, Ye W, Nyrén O, Normark S, Engstrand L.

PLoS One. 2011;6(10):e26442. doi: 10.1371/journal.pone.0026442. Epub 2011 Oct 21.


Studies on the antibacterial effects of statins--in vitro and in vivo.

Bergman P, Linde C, Pütsep K, Pohanka A, Normark S, Henriques-Normark B, Andersson J, Björkhem-Bergman L.

PLoS One. 2011;6(8):e24394. doi: 10.1371/journal.pone.0024394. Epub 2011 Aug 30.

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