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Items: 1 to 20 of 25


Genome-Scale Architecture of Small Molecule Regulatory Networks and the Fundamental Trade-Off between Regulation and Enzymatic Activity.

Reznik E, Christodoulou D, Goldford JE, Briars E, Sauer U, Segrè D, Noor E.

Cell Rep. 2017 Sep 12;20(11):2666-2677. doi: 10.1016/j.celrep.2017.08.066.


Design principles of autocatalytic cycles constrain enzyme kinetics and force low substrate saturation at flux branch points.

Barenholz U, Davidi D, Reznik E, Bar-On Y, Antonovsky N, Noor E, Milo R.

Elife. 2017 Feb 7;6. pii: e20667. doi: 10.7554/eLife.20667.


The Protein Cost of Metabolic Fluxes: Prediction from Enzymatic Rate Laws and Cost Minimization.

Noor E, Flamholz A, Bar-Even A, Davidi D, Milo R, Liebermeister W.

PLoS Comput Biol. 2016 Nov 3;12(11):e1005167. doi: 10.1371/journal.pcbi.1005167. eCollection 2016 Nov.


Sugar Synthesis from CO2 in Escherichia coli.

Antonovsky N, Gleizer S, Noor E, Zohar Y, Herz E, Barenholz U, Zelcbuch L, Amram S, Wides A, Tepper N, Davidi D, Bar-On Y, Bareia T, Wernick DG, Shani I, Malitsky S, Jona G, Bar-Even A, Milo R.

Cell. 2016 Jun 30;166(1):115-25. doi: 10.1016/j.cell.2016.05.064. Epub 2016 Jun 23.


Integrated In Silico Analysis of Pathway Designs for Synthetic Photo-Electro-Autotrophy.

Volpers M, Claassens NJ, Noor E, van der Oost J, de Vos WM, Kengen SW, Martins Dos Santos VA.

PLoS One. 2016 Jun 23;11(6):e0157851. doi: 10.1371/journal.pone.0157851. eCollection 2016.


SBtab: a flexible table format for data exchange in systems biology.

Lubitz T, Hahn J, Bergmann FT, Noor E, Klipp E, Liebermeister W.

Bioinformatics. 2016 Aug 15;32(16):2559-61. doi: 10.1093/bioinformatics/btw179. Epub 2016 Apr 8.


Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro kcat measurements.

Davidi D, Noor E, Liebermeister W, Bar-Even A, Flamholz A, Tummler K, Barenholz U, Goldenfeld M, Shlomi T, Milo R.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3401-6. doi: 10.1073/pnas.1514240113. Epub 2016 Mar 7.


Computational protein design enables a novel one-carbon assimilation pathway.

Siegel JB, Smith AL, Poust S, Wargacki AJ, Bar-Even A, Louw C, Shen BW, Eiben CB, Tran HM, Noor E, Gallaher JL, Bale J, Yoshikuni Y, Gelb MH, Keasling JD, Stoddard BL, Lidstrom ME, Baker D.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3704-9. doi: 10.1073/pnas.1500545112. Epub 2015 Mar 9.


Molecular markers and cotton genetic improvement: current status and future prospects.

Malik W, Ashraf J, Iqbal MZ, Khan AA, Qayyum A, Ali Abid M, Noor E, Ahmad MQ, Abbasi GH.

ScientificWorldJournal. 2014;2014:607091. doi: 10.1155/2014/607091. Epub 2014 Oct 23. Review.


Quantum chemical approach to estimating the thermodynamics of metabolic reactions.

Jinich A, Rappoport D, Dunn I, Sanchez-Lengeling B, Olivares-Amaya R, Noor E, Even AB, Aspuru-Guzik A.

Sci Rep. 2014 Nov 12;4:7022. doi: 10.1038/srep07022.


Intravenous thrombolysis in a patient using factor Xa inhibitor.

Korya D, Dababneh H, Moussavi M, Panezai S, Noor E, Kirmani JF.

J Vasc Interv Neurol. 2014 Sep;7(3):1-4.


Visual account of protein investment in cellular functions.

Liebermeister W, Noor E, Flamholz A, Davidi D, Bernhardt J, Milo R.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8488-93. doi: 10.1073/pnas.1314810111. Epub 2014 Jun 2.


Pathway thermodynamics highlights kinetic obstacles in central metabolism.

Noor E, Bar-Even A, Flamholz A, Reznik E, Liebermeister W, Milo R.

PLoS Comput Biol. 2014 Feb 20;10(2):e1003483. doi: 10.1371/journal.pcbi.1003483. eCollection 2014 Feb.


Steady-state metabolite concentrations reflect a balance between maximizing enzyme efficiency and minimizing total metabolite load.

Tepper N, Noor E, Amador-Noguez D, Haraldsdóttir HS, Milo R, Rabinowitz J, Liebermeister W, Shlomi T.

PLoS One. 2013 Sep 26;8(9):e75370. doi: 10.1371/journal.pone.0075370. eCollection 2013.


Consistent estimation of Gibbs energy using component contributions.

Noor E, Haraldsdóttir HS, Milo R, Fleming RM.

PLoS Comput Biol. 2013;9(7):e1003098. doi: 10.1371/journal.pcbi.1003098. Epub 2013 Jul 11.


Glycolytic strategy as a tradeoff between energy yield and protein cost.

Flamholz A, Noor E, Bar-Even A, Liebermeister W, Milo R.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):10039-44. doi: 10.1073/pnas.1215283110. Epub 2013 Apr 29.


Spanning high-dimensional expression space using ribosome-binding site combinatorics.

Zelcbuch L, Antonovsky N, Bar-Even A, Levin-Karp A, Barenholz U, Dayagi M, Liebermeister W, Flamholz A, Noor E, Amram S, Brandis A, Bareia T, Yofe I, Jubran H, Milo R.

Nucleic Acids Res. 2013 May;41(9):e98. doi: 10.1093/nar/gkt151. Epub 2013 Mar 6.


A proof for loop-law constraints in stoichiometric metabolic networks.

Noor E, Lewis NE, Milo R.

BMC Syst Biol. 2012 Nov 12;6:140. doi: 10.1186/1752-0509-6-140.


An integrated open framework for thermodynamics of reactions that combines accuracy and coverage.

Noor E, Bar-Even A, Flamholz A, Lubling Y, Davidi D, Milo R.

Bioinformatics. 2012 Aug 1;28(15):2037-44. doi: 10.1093/bioinformatics/bts317. Epub 2012 May 29.


eQuilibrator--the biochemical thermodynamics calculator.

Flamholz A, Noor E, Bar-Even A, Milo R.

Nucleic Acids Res. 2012 Jan;40(Database issue):D770-5. doi: 10.1093/nar/gkr874. Epub 2011 Nov 7.

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