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Items: 1 to 20 of 33

1.

The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.

Biernacka JM, Sangkuhl K, Jenkins G, Whaley RM, Barman P, Batzler A, Altman RB, Arolt V, Brockmöller J, Chen CH, Domschke K, Hall-Flavin DK, Hong CJ, Illi A, Ji Y, Kampman O, Kinoshita T, Leinonen E, Liou YJ, Mushiroda T, Nonen S, Skime MK, Wang L, Baune BT, Kato M, Liu YL, Praphanphoj V, Stingl JC, Tsai SJ, Kubo M, Klein TE, Weinshilboum R.

Transl Psychiatry. 2016 Nov 1;6(11):e937. doi: 10.1038/tp.2016.187. No abstract available.

2.

Polymorphism of rs3813034 in Serotonin Transporter Gene SLC6A4 Is Associated With the Selective Serotonin and Serotonin-Norepinephrine Reuptake Inhibitor Response in Depressive Disorder: Sequencing Analysis of SLC6A4.

Nonen S, Kato M, Takekita Y, Wakeno M, Sakai S, Serretti A, Kinoshita T.

J Clin Psychopharmacol. 2016 Feb;36(1):27-31. doi: 10.1097/JCP.0000000000000454.

PMID:
26674707
3.

Neuropsychological Evaluation and Cerebral Blood Flow Effects of Apolipoprotein E4 in Alzheimer's Disease Patients after One Year of Treatment: An Exploratory Study.

Suwa A, Nishida K, Utsunomiya K, Nonen S, Yoshimura M, Takekita Y, Wakeno M, Tajika A, Yoshino M, Koshikawa Y, Kato M, Kinoshita T.

Dement Geriatr Cogn Dis Extra. 2015 Oct 22;5(3):414-23. doi: 10.1159/000440714. eCollection 2015 Sep-Dec.

4.

Serotonin 7 Receptor Variants Are Not Associated with Response to Second-Generation Antipsychotics in Japanese Schizophrenia Patients.

Takekita Y, Fabbri C, Kato M, Nonen S, Sakai S, Sunada N, Koshikawa Y, Wakeno M, Okugawa G, Kinoshita T, Serretti A.

Neuropsychobiology. 2015;72(2):118-25. doi: 10.1159/000441629. Epub 2015 Nov 27.

PMID:
26609891
5.

Antagonist and partial agonist at the dopamine D2 receptors in drug-naïve and non-drug-naïve schizophrenia: a randomized, controlled trial.

Takekita Y, Fabbri C, Kato M, Nonen S, Sakai S, Sunada N, Koshikawa Y, Wakeno M, Okugawa G, Kinoshita T, Serretti A.

Eur Arch Psychiatry Clin Neurosci. 2015 Oct;265(7):579-88. doi: 10.1007/s00406-015-0605-1. Epub 2015 May 28.

PMID:
26016467
6.

The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.

Biernacka JM, Sangkuhl K, Jenkins G, Whaley RM, Barman P, Batzler A, Altman RB, Arolt V, Brockmöller J, Chen CH, Domschke K, Hall-Flavin DK, Hong CJ, Illi A, Ji Y, Kampman O, Kinoshita T, Leinonen E, Liou YJ, Mushiroda T, Nonen S, Skime MK, Wang L, Baune BT, Kato M, Liu YL, Praphanphoj V, Stingl JC, Tsai SJ, Kubo M, Klein TE, Weinshilboum R.

Transl Psychiatry. 2015 Apr 21;5:e553. doi: 10.1038/tp.2015.47.

7.

HTR1A Gene Polymorphisms and 5-HT1A Receptor Partial Agonist Antipsychotics Efficacy in Schizophrenia.

Takekita Y, Fabbri C, Kato M, Nonen S, Sakai S, Sunada N, Koshikawa Y, Wakeno M, Okugawa G, Kinoshita T, Serretti A.

J Clin Psychopharmacol. 2015 Jun;35(3):220-7. doi: 10.1097/JCP.0000000000000304.

PMID:
25822479
8.

Genetic variants in combination with early partial improvement as a clinical utility predictor of treatment outcome in major depressive disorder: the result of two pooled RCTs.

Kato M, Serretti A, Nonen S, Takekita Y, Wakeno M, Azuma J, Kinoshita T.

Transl Psychiatry. 2015 Feb 24;5:e513. doi: 10.1038/tp.2015.6.

9.

Polymorphisms of CYP2D6 gene and gefitinib-induced hepatotoxicity.

Takimoto T, Kijima T, Otani Y, Nonen S, Namba Y, Mori M, Yokota S, Minami S, Komuta K, Uchida J, Imamura F, Furukawa M, Tsuruta N, Fujio Y, Azuma J, Tachibana I, Kumanogoh A.

Clin Lung Cancer. 2013 Sep;14(5):502-7. doi: 10.1016/j.cllc.2013.03.003. Epub 2013 May 9.

PMID:
23664723
10.

5-HTTLPR rs25531A > G differentially influence paroxetine and fluvoxamine antidepressant efficacy: a randomized, controlled trial.

Kato M, Nonen S, Serretti A, Tetsuo S, Takekita Y, Azuma J, Kinoshita T.

J Clin Psychopharmacol. 2013 Feb;33(1):131-2. doi: 10.1097/01.jcp.0000426182.66701.76. No abstract available.

PMID:
23288236
11.

5-HTTLPR rs25531A > G Differentially Influence Paroxetine and Fluvoxamine Antidepressant Efficacy: A Randomized Controlled Trial.

Kato M, Nonen S, Serretti A, Tetsuo S, Takekita Y, Azuma J, Kinoshita T.

J Clin Psychopharmacol. 2012 Dec 28. [Epub ahead of print] No abstract available.

PMID:
23277270
12.

Minimal dose for effective clinical outcome and predictive factors for responsiveness to carvedilol: Japanese chronic heart failure (J-CHF) study.

Okamoto H, Hori M, Matsuzaki M, Tsutsui H, Yamazaki T, Nagai R, Yoshikawa T, Fujio Y, Nonen S, Azuma J, Izumi T, Ohashi Y, Kitabatake A; J-CHF Investigators..

Int J Cardiol. 2013 Apr 5;164(2):238-44. doi: 10.1016/j.ijcard.2012.11.051. Epub 2012 Dec 12.

13.

NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: a randomized controlled trial for pharmacogenetics-based therapy.

Azuma J, Ohno M, Kubota R, Yokota S, Nagai T, Tsuyuguchi K, Okuda Y, Takashima T, Kamimura S, Fujio Y, Kawase I; Pharmacogenetics-based tuberculosis therapy research group..

Eur J Clin Pharmacol. 2013 May;69(5):1091-101. doi: 10.1007/s00228-012-1429-9. Epub 2012 Nov 14.

14.

Genetic polymorphisms of CYP17A1 in steroidogenesis pathway are associated with risk of progression to castration-resistant prostate cancer in Japanese men receiving androgen deprivation therapy.

Yamada T, Nakayama M, Shimizu T, Nonen S, Nakai Y, Nishimura K, Fujio Y, Okuyama A, Azuma J, Nonomura N.

Int J Clin Oncol. 2013 Aug;18(4):711-7. doi: 10.1007/s10147-012-0430-8. Epub 2012 Jun 21.

PMID:
22714708
15.

Genome-wide association study of SSRI/SNRI-induced sexual dysfunction in a Japanese cohort with major depression.

Kurose K, Hiratsuka K, Ishiwata K, Nishikawa J, Nonen S, Azuma J, Kato M, Wakeno M, Okugawa G, Kinoshita T, Kurosawa T, Hasegawa R, Saito Y.

Psychiatry Res. 2012 Aug 15;198(3):424-9. doi: 10.1016/j.psychres.2012.01.023. Epub 2012 Mar 23.

PMID:
22445761
16.

Safe and successful treatment with erlotinib after gefitinib-induced hepatotoxicity: difference in metabolism as a possible mechanism.

Kijima T, Shimizu T, Nonen S, Furukawa M, Otani Y, Minami T, Takahashi R, Hirata H, Nagatomo I, Takeda Y, Kida H, Goya S, Fujio Y, Azuma J, Tachibana I, Kawase I.

J Clin Oncol. 2011 Jul 1;29(19):e588-90. doi: 10.1200/JCO.2010.34.3368. Epub 2011 Apr 18. No abstract available.

PMID:
21502555
17.

Cigarette smoke extract induces CYP2B6 through constitutive androstane receptor in hepatocytes.

Washio I, Maeda M, Sugiura C, Shiga R, Yoshida M, Nonen S, Fujio Y, Azuma J.

Drug Metab Dispos. 2011 Jan;39(1):1-3. doi: 10.1124/dmd.110.034504. Epub 2010 Oct 21.

18.

Simple and accurate determination of CYP2D6 gene copy number by a loop-mediated isothermal amplification method and an electrochemical DNA chip.

Nakamura N, Fukuda T, Nonen S, Hashimoto K, Azuma J, Gemma N.

Clin Chim Acta. 2010 Apr 2;411(7-8):568-73. doi: 10.1016/j.cca.2010.01.017. Epub 2010 Jan 20.

PMID:
20093110
19.

[Genetic polymorphism of CYP-450 in drug development].

Nonen S, Azuma J.

Nihon Yakurigaku Zasshi. 2009 Oct;134(4):212-5. Review. Japanese. No abstract available.

PMID:
19828926
20.

Effect of basic fibroblast growth factor (FGF2) gene polymorphisms on SSRIs treatment response and side effects.

Kato M, Okugawa G, Wakeno M, Takekita Y, Nonen S, Tetsuo S, Nishida K, Azuma J, Kinoshita T, Serretti A.

Eur Neuropsychopharmacol. 2009 Oct;19(10):718-25. doi: 10.1016/j.euroneuro.2009.06.006. Epub 2009 Jul 7. Erratum in: Eur Neuropsychopharmacol. 2010 Feb;20(2):137.

PMID:
19586755

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