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Items: 1 to 20 of 36

1.

Perfect merohedral twinning combined with noncrystallographic symmetry potentially causes the failure of molecular replacement with low-homology search models for the flavin-dependent halogenase HalX from Xanthomonas campestris.

Buss M, Geerds C, Patschkowski T, Niehaus K, Niemann HH.

Acta Crystallogr F Struct Biol Commun. 2018 Jun 1;74(Pt 6):345-350. doi: 10.1107/S2053230X18006933. Epub 2018 May 18.

PMID:
29870018
2.

A flavin-dependent halogenase from metagenomic analysis prefers bromination over chlorination.

Neubauer PR, Widmann C, Wibberg D, Schröder L, Frese M, Kottke T, Kalinowski J, Niemann HH, Sewald N.

PLoS One. 2018 May 10;13(5):e0196797. doi: 10.1371/journal.pone.0196797. eCollection 2018.

3.

Membrane dynamics of resting and internalin B-bound MET receptor tyrosine kinase studied by single-molecule tracking.

Harwardt MIE, Young P, Bleymüller WM, Meyer T, Karathanasis C, Niemann HH, Heilemann M, Dietz MS.

FEBS Open Bio. 2017 Aug 29;7(9):1422-1440. doi: 10.1002/2211-5463.12285. eCollection 2017 Sep.

4.

MET-activating Residues in the B-repeat of the Listeria monocytogenes Invasion Protein InlB.

Bleymüller WM, Lämmermann N, Ebbes M, Maynard D, Geerds C, Niemann HH.

J Biol Chem. 2016 Dec 2;291(49):25567-25577. Epub 2016 Oct 27.

5.

Crystal structure of Halobacterium salinarum halorhodopsin with a partially depopulated primary chloride-binding site.

Schreiner M, Schlesinger R, Heberle J, Niemann HH.

Acta Crystallogr F Struct Biol Commun. 2016 Sep;72(Pt 9):692-9. doi: 10.1107/S2053230X16012796. Epub 2016 Aug 26.

PMID:
27599860
6.

Live cell imaging shows hepatocyte growth factor-induced Met dimerization.

Koschut D, Richert L, Pace G, Niemann HH, Mély Y, Orian-Rousseau V.

Biochim Biophys Acta. 2016 Jul;1863(7 Pt A):1552-8. doi: 10.1016/j.bbamcr.2016.04.015. Epub 2016 Apr 17.

7.

Direct binding of hepatocyte growth factor and vascular endothelial growth factor to CD44v6.

Volz Y, Koschut D, Matzke-Ogi A, Dietz MS, Karathanasis C, Richert L, Wagner MG, Mély Y, Heilemann M, Niemann HH, Orian-Rousseau V.

Biosci Rep. 2015 Jun 29;35(4). pii: e00236. doi: 10.1042/BSR20150093.

8.

Structure of Halorhodopsin from Halobacterium salinarum in a new crystal form that imposes little restraint on the E-F loop.

Schreiner M, Schlesinger R, Heberle J, Niemann HH.

J Struct Biol. 2015 Jun;190(3):373-8. doi: 10.1016/j.jsb.2015.04.010. Epub 2015 Apr 24.

PMID:
25916754
9.

Adhesion of several cell lines to Helicobacter pylori CagL is mediated by integrin αVβ6 via an RGDLXXL motif.

Barden S, Niemann HH.

J Mol Biol. 2015 Mar 27;427(6 Pt B):1304-1315. doi: 10.1016/j.jmb.2015.01.006. Epub 2015 Jan 21.

PMID:
25617764
10.

Structure of Rhodococcus equi virulence-associated protein B (VapB) reveals an eight-stranded antiparallel β-barrel consisting of two Greek-key motifs.

Geerds C, Wohlmann J, Haas A, Niemann HH.

Acta Crystallogr F Struct Biol Commun. 2014 Jul;70(Pt 7):866-71. doi: 10.1107/S2053230X14009911. Epub 2014 Jun 18.

11.

Structure of a three-dimensional domain-swapped dimer of the Helicobacter pylori type IV secretion system pilus protein CagL.

Barden S, Schomburg B, Conradi J, Backert S, Sewald N, Niemann HH.

Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1391-400. doi: 10.1107/S1399004714003150. Epub 2014 Apr 30.

PMID:
24816107
12.

Receptor-ligand interactions: binding affinities studied by single-molecule and super-resolution microscopy on intact cells.

Dietz MS, Fricke F, Krüger CL, Niemann HH, Heilemann M.

Chemphyschem. 2014 Mar 17;15(4):671-6.

PMID:
24772464
13.

Crystal structure of an engineered YopM-InlB hybrid protein.

Breitsprecher D, Gherardi E, Bleymüller WM, Niemann HH.

BMC Struct Biol. 2014 Mar 27;14:12. doi: 10.1186/1472-6807-14-12.

14.

Wound healing potential of a dimeric InlB variant analyzed by in vitro experiments on re-epithelialization of human skin models.

Kolditz F, Krausze J, Heinz DW, Niemann HH, Müller-Goymann CC.

Eur J Pharm Biopharm. 2014 Feb;86(2):277-83. doi: 10.1016/j.ejpb.2013.10.003. Epub 2013 Oct 15.

PMID:
24140590
15.

A helical RGD motif promoting cell adhesion: crystal structures of the Helicobacter pylori type IV secretion system pilus protein CagL.

Barden S, Lange S, Tegtmeyer N, Conradi J, Sewald N, Backert S, Niemann HH.

Structure. 2013 Nov 5;21(11):1931-41. doi: 10.1016/j.str.2013.08.018. Epub 2013 Sep 26.

16.

Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cells.

Dietz MS, Haße D, Ferraris DM, Göhler A, Niemann HH, Heilemann M.

BMC Biophys. 2013 Jun 3;6(1):6. doi: 10.1186/2046-1682-6-6.

17.

Structural basis of MET receptor dimerization by the bacterial invasion protein InlB and the HGF/SF splice variant NK1.

Niemann HH.

Biochim Biophys Acta. 2013 Oct;1834(10):2195-204. doi: 10.1016/j.bbapap.2012.10.012. Epub 2012 Oct 31. Review.

PMID:
23123275
18.

Engineered variants of InlB with an additional leucine-rich repeat discriminate between physiologically relevant and packing contacts in crystal structures of the InlB:MET complex.

Niemann HH, Gherardi E, Bleymüller WM, Heinz DW.

Protein Sci. 2012 Oct;21(10):1528-39. doi: 10.1002/pro.2142. Epub 2012 Sep 17.

19.
20.

The unusual extended C-terminal helix of the peroxisomal α/β-hydrolase Lpx1 is involved in dimer contacts but dispensable for dimerization.

Thoms S, Hofhuis J, Thöing C, Gärtner J, Niemann HH.

J Struct Biol. 2011 Sep;175(3):362-71. doi: 10.1016/j.jsb.2011.06.008. Epub 2011 Jun 29.

PMID:
21741480

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