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Items: 1 to 20 of 235

1.

Cell-free Pipeline for Discovery of Thermotolerant Xylanases and Endo-1,4-β-Glucanases.

Gagoski D, Shi Z, Nielsen LK, Vickers CE, Mahler S, Speight R, Johnston WA, Alexandrov K.

J Biotechnol. 2017 Jul 17. pii: S0168-1656(17)31526-2. doi: 10.1016/j.jbiotec.2017.07.014. [Epub ahead of print]

PMID:
28728936
2.

Awakening sleeping beauty: production of propionic acid in Escherichia coli through the sbm operon requires the activity of a methylmalonyl-CoA epimerase.

Gonzalez-Garcia RA, McCubbin T, Wille A, Plan M, Nielsen LK, Marcellin E.

Microb Cell Fact. 2017 Jul 17;16(1):121. doi: 10.1186/s12934-017-0735-4.

3.

Maintenance of ATP Homeostasis Triggers Metabolic Shifts in Gas-Fermenting Acetogens.

Valgepea K, de Souza Pinto Lemgruber R, Meaghan K, Palfreyman RW, Abdalla T, Heijstra BD, Behrendorff JB, Tappel R, Köpke M, Simpson SD, Nielsen LK, Marcellin E.

Cell Syst. 2017 May 24;4(5):505-515.e5. doi: 10.1016/j.cels.2017.04.008. Epub 2017 May 17.

PMID:
28527885
4.

Arginine deiminase pathway provides ATP and boosts growth of the gas-fermenting acetogen Clostridium autoethanogenum.

Valgepea K, Loi KQ, Behrendorff JB, Lemgruber RSP, Plan M, Hodson MP, Köpke M, Nielsen LK, Marcellin E.

Metab Eng. 2017 May;41:202-211. doi: 10.1016/j.ymben.2017.04.007. Epub 2017 Apr 23.

PMID:
28442386
5.

Overexpression of the regulatory subunit of glutamate-cysteine ligase enhances monoclonal antibody production in CHO cells.

Orellana CA, Marcellin E, Gray PP, Nielsen LK.

Biotechnol Bioeng. 2017 Aug;114(8):1825-1836. doi: 10.1002/bit.26316. Epub 2017 May 8.

PMID:
28436007
6.

A systematic review of health-related quality of life in longitudinal studies of myeloma patients.

Nielsen LK, Jarden M, Andersen CL, Frederiksen H, Abildgaard N.

Eur J Haematol. 2017 Jul;99(1):3-17. doi: 10.1111/ejh.12882. Epub 2017 Apr 25. Review.

PMID:
28322018
7.

Coupling gene regulatory patterns to bioprocess conditions to optimize synthetic metabolic modules for improved sesquiterpene production in yeast.

Peng B, Plan MR, Carpenter A, Nielsen LK, Vickers CE.

Biotechnol Biofuels. 2017 Feb 21;10:43. doi: 10.1186/s13068-017-0728-x. eCollection 2017.

8.

A squalene synthase protein degradation method for improved sesquiterpene production in Saccharomyces cerevisiae.

Peng B, Plan MR, Chrysanthopoulos P, Hodson MP, Nielsen LK, Vickers CE.

Metab Eng. 2017 Jan;39:209-219. doi: 10.1016/j.ymben.2016.12.003. Epub 2016 Dec 8.

PMID:
27939849
9.

Hand bone loss in early rheumatoid arthritis during a methotrexate-based treat-to-target strategy with or without adalimumab-a substudy of the optimized treatment algorithm in early RA (OPERA) trial.

Ørnbjerg LM, Østergaard M, Jensen T, Hørslev-Petersen K, Stengaard-Pedersen K, Junker P, Ellingsen T, Ahlquist P, Lindegaard H, Linauskas A, Schlemmer A, Dam MY, Hansen I, Lottenburger T, Ammitzbøll CG, Jørgensen A, Krintel SB, Raun J, Hetland ML; OPERA Study Group, Slot O, Nielsen LK, Skjødt H, Majgaard O, Lorenzen T, Horn HC, Kowalski M, Johansen IL, Pedersen PM, Manilo N, Bliddal H.

Clin Rheumatol. 2017 Apr;36(4):781-789. doi: 10.1007/s10067-016-3489-1. Epub 2016 Dec 5.

PMID:
27921185
10.

A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism.

Hefzi H, Ang KS, Hanscho M, Bordbar A, Ruckerbauer D, Lakshmanan M, Orellana CA, Baycin-Hizal D, Huang Y, Ley D, Martinez VS, Kyriakopoulos S, Jiménez NE, Zielinski DC, Quek LE, Wulff T, Arnsdorf J, Li S, Lee JS, Paglia G, Loira N, Spahn PN, Pedersen LE, Gutierrez JM, King ZA, Lund AM, Nagarajan H, Thomas A, Abdel-Haleem AM, Zanghellini J, Kildegaard HF, Voldborg BG, Gerdtzen ZP, Betenbaugh MJ, Palsson BO, Andersen MR, Nielsen LK, Borth N, Lee DY, Lewis NE.

Cell Syst. 2016 Nov 23;3(5):434-443.e8. doi: 10.1016/j.cels.2016.10.020.

PMID:
27883890
11.

Improved production of propionic acid using genome shuffling.

Luna-Flores CH, Palfreyman RW, Krömer JO, Nielsen LK, Marcellin E.

Biotechnol J. 2017 Feb;12(2). doi: 10.1002/biot.201600120. Epub 2016 Oct 20.

PMID:
27676587
12.

In vitro production of baculoviruses: identifying host and virus genes associated with high productivity.

Nguyen Q, Tb Tran T, Chan LC, Nielsen LK, Reid S.

Appl Microbiol Biotechnol. 2016 Nov;100(21):9239-9253. Epub 2016 Sep 9.

PMID:
27613424
13.

Metabolic Reconstruction of Setaria italica: A Systems Biology Approach for Integrating Tissue-Specific Omics and Pathway Analysis of Bioenergy Grasses.

de Oliveira Dal'Molin CG, Orellana C, Gebbie L, Steen J, Hodson MP, Chrysanthopoulos P, Plan MR, McQualter R, Palfreyman RW, Nielsen LK.

Front Plant Sci. 2016 Aug 10;7:1138. doi: 10.3389/fpls.2016.01138. eCollection 2016.

14.

Fast-SNP: a fast matrix pre-processing algorithm for efficient loopless flux optimization of metabolic models.

Saa PA, Nielsen LK.

Bioinformatics. 2016 Dec 15;32(24):3807-3814. Epub 2016 Aug 24.

15.

Spliced synthetic genes as internal controls in RNA sequencing experiments.

Hardwick SA, Chen WY, Wong T, Deveson IW, Blackburn J, Andersen SB, Nielsen LK, Mattick JS, Mercer TR.

Nat Methods. 2016 Sep;13(9):792-8. doi: 10.1038/nmeth.3958. Epub 2016 Aug 8.

PMID:
27502218
16.

Representing genetic variation with synthetic DNA standards.

Deveson IW, Chen WY, Wong T, Hardwick SA, Andersen SB, Nielsen LK, Mattick JS, Mercer TR.

Nat Methods. 2016 Sep;13(9):784-91. doi: 10.1038/nmeth.3957. Epub 2016 Aug 8.

PMID:
27502217
17.

Tetanus toxin production is triggered by the transition from amino acid consumption to peptides.

Licona-Cassani C, Steen JA, Zaragoza NE, Moonen G, Moutafis G, Hodson MP, Power J, Nielsen LK, Marcellin E.

Anaerobe. 2016 Oct;41:113-124. doi: 10.1016/j.anaerobe.2016.07.006. Epub 2016 Aug 1.

18.

Retrospective evaluation of the incidence and prognostic significance of spontaneous echocardiographic contrast in relation to cardiac disease and congestive heart failure in cats: 725 cases (2006-2011).

Peck CM, Nielsen LK, Quinn RL, Laste NJ, Price LL.

J Vet Emerg Crit Care (San Antonio). 2016 Sep;26(5):704-12. doi: 10.1111/vec.12509. Epub 2016 Aug 1.

PMID:
27479924
19.

Construction of feasible and accurate kinetic models of metabolism: A Bayesian approach.

Saa PA, Nielsen LK.

Sci Rep. 2016 Jul 15;6:29635. doi: 10.1038/srep29635.

20.

Genomic characterization of the uncultured Bacteroidales family S24-7 inhabiting the guts of homeothermic animals.

Ormerod KL, Wood DL, Lachner N, Gellatly SL, Daly JN, Parsons JD, Dal'Molin CG, Palfreyman RW, Nielsen LK, Cooper MA, Morrison M, Hansbro PM, Hugenholtz P.

Microbiome. 2016 Jul 7;4(1):36. doi: 10.1186/s40168-016-0181-2.

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